Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Viveka Mayya"'
Autor:
Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin, Uzi Gileadi, Salvatore Valvo, Margarida Rei, Corinna Kulicke, Ji-Li Chen, Vitul Jain, Victoria K. Woodcock, Huw Colin-York, Andreas V. Hadjinicolaou, Youxin Kong, Viveka Mayya, Julie M. Mazet, Gracie-Jennah Mead, Joshua A. Bull, Pramila Rijal, Christopher W. Pugh, Alain R. Townsend, Audrey Gérard, Lars R. Olsen, Marco Fritzsche, Tudor A. Fulga, Michael L. Dustin, E. Yvonne Jones, Vincenzo Cerundolo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Semaphorin-3A (SEMA3A) functions as a chemorepulsive signal during development and can affect T cells by altering their filamentous actin (F-actin) cytoskeleton. The exact extent of these effects on tumour-specific T cells are not completely
Externí odkaz:
https://doaj.org/article/0037fd20318049ccb1e0d08f25e77331
Autor:
Mike B. Barnkob, Yale S. Michaels, Violaine André, Philip S. Macklin, Uzi Gileadi, Salvatore Valvo, Margarida Rei, Corinna Kulicke, Ji-Li Chen, Vitul Jain, Victoria K. Woodcock, Huw Colin-York, Andreas V. Hadjinicolaou, Youxin Kong, Viveka Mayya, Julie M. Mazet, Gracie-Jennah Mead, Joshua A. Bull, Pramila Rijal, Christopher W. Pugh, Alain R. Townsend, Audrey Gérard, Lars R. Olsen, Marco Fritzsche, Tudor A. Fulga, Michael L. Dustin, E. Yvonne Jones, Vincenzo Cerundolo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/c91684507e624290b137868f21bb7e7e
Autor:
Anastasios Siokis, Philippe A. Robert, Philippos Demetriou, Audun Kvalvaag, Salvatore Valvo, Viveka Mayya, Michael L. Dustin, Michael Meyer-Hermann
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103100- (2021)
Summary: Small immunoglobulin superfamily (sIGSF) adhesion complexes form a corolla of microdomains around an integrin ring and secretory core during immunological synapse (IS) formation. The corolla recruits and retains major costimulatory/checkpoin
Externí odkaz:
https://doaj.org/article/1961a091187641ce8d77cb84243f0b4a
Autor:
Viveka Mayya, Edward Judokusumo, Enas Abu Shah, Christopher G. Peel, Willie Neiswanger, David Depoil, David A. Blair, Chris H. Wiggins, Lance C. Kam, Michael L. Dustin
Publikováno v:
Cell Reports, Vol 22, Iss 2, Pp 340-349 (2018)
Summary: T cells engage in two modes of interaction with antigen-presenting surfaces: stable synapses and motile kinapses. Although it is surmised that durable interactions of T cells with antigen-presenting cells involve synapses, in situ 3D imaging
Externí odkaz:
https://doaj.org/article/dd677668e2df4a0db8e025ca66ed90b4
Autor:
Enas Abu-Shah, Philippos Demetriou, Štefan Bálint, Viveka Mayya, Mikhail A Kutuzov, Omer Dushek, Michael L Dustin
Publikováno v:
eLife, Vol 8 (2019)
Research in the field of human immunology is restricted by the lack of a system that reconstitutes the in-situactivation dynamics of quiescent human antigen-specific T-cells interacting with dendritic cells. Here we report a tissue-like system that r
Externí odkaz:
https://doaj.org/article/7078a64cb83b480cb219dd2e3e856c67
Autor:
David G Saliba, Pablo F Céspedes-Donoso, Štefan Bálint, Ewoud B Compeer, Kseniya Korobchevskaya, Salvatore Valvo, Viveka Mayya, Audun Kvalvaag, Yanchun Peng, Tao Dong, Maria-Laura Tognoli, Eric O'Neill, Sarah Bonham, Roman Fischer, Benedikt M Kessler, Michael L Dustin
Publikováno v:
eLife, Vol 8 (2019)
Planar supported lipid bilayers (PSLB) presenting T cell receptor (TCR) ligands and ICAM-1 induce budding of extracellular microvesicles enriched in functional TCR, defined here as synaptic ectosomes (SE), from helper T cells. SE bind peptide-MHC dir
Externí odkaz:
https://doaj.org/article/40ca633e770d440aa82c9062daa1f80b
Autor:
Salvatore Valvo, Michael Meyer-Hermann, Michael L. Dustin, Philippe Robert, Viveka Mayya, Anastasios Siokis, Philippos Demetriou, A Kvalvaag
Publikováno v:
iScience
iScience, Vol 24, Iss 10, Pp 103100-(2021)
iScience, Vol 24, Iss 10, Pp 103100-(2021)
Summary Small immunoglobulin superfamily (sIGSF) adhesion complexes form a corolla of microdomains around an integrin ring and secretory core during immunological synapse (IS) formation. The corolla recruits and retains major costimulatory/checkpoint
Characterization of Mechanisms Positioning Costimulatory and Checkpoint Complexes in Immune Synapses
Autor:
Anastasios Siokis, Philippe Auguste Robert, Philippos Demetriou, Audun Kvalvaag, Salvatore Valvo, Viveka Mayya, Michael L. Dustin, Michael Meyer-Hermann
Publikováno v:
SSRN Electronic Journal.
Autor:
Salvatore Valvo, Philippe Robert, Michael L. Dustin, Viveka Mayya, Michael Meyer-Hermann, A Kvalvaag, Anastasios Siokis, Philippos Demetriou
Integrin and small immunoglobulin superfamily (sIGSF) adhesion complexes function physiologically in human immunological synapses (IS) wherein sIGSF complexes form a corolla of microdomains around an integrin ring and secretory core. The corolla recr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df7d5e545bc0fe2247f6b37a2a2a27f6
Autor:
Yazhuo Kong, Viveka Mayya, M Rei, Christopher W. Pugh, Michael L. Dustin, Lars Rønn Olsen, Tudor A. Fulga, Victoria K Woodcock, Kulicke Ca, Marco Fritzsche, V. Jain, Andreas V. Hadjinicolaou, E Y Jones, Chen J-L., V Andre, Pramila Rijal, Mike Bogetofte Barnkob, Joshua A. Bull, Uzi Gileadi, Huw Colin-York, Vincenzo Cerundolo, Salvatore Valvo, Alain Townsend, Yale S. Michaels, Philip S. Macklin
Semaphorin-3A (Sema3A) regulates tumor angiogenesis, but its role in modulating anti-tumor immunity is unclear. We demonstrate that Sema3A secreted within the tumor microenvironment (TME) suppresses tumor-specific CD8+ T cell function via Neuropilin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3695ba007bc288ca11964d5920f42855