Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Vivek Sudhakar"'
Autor:
Kousaku Ohno, Lluis Samaranch, Piotr Hadaczek, John R. Bringas, Philip C. Allen, Vivek Sudhakar, Diane E. Stockinger, Christopher Snieckus, Michael V. Campagna, Waldy San Sebastian, Jerusha Naidoo, Haifeng Chen, John Forsayeth, Ernesto A. Salegio, Granger G.C. Hwa, Krystof S. Bankiewicz
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 47-54 (2019)
Here we evaluated the utility of MRI to monitor intrathecal infusions in nonhuman primates. Adeno-associated virus (AAV) spiked with gadoteridol, a gadolinium-based MRI contrast agent, enabled real-time visualization of infusions delivered either via
Externí odkaz:
https://doaj.org/article/5a819b72674d4e9490c437bdab03d8bd
Autor:
Piotr Hadaczek, Lisa Stanek, Agnieszka Ciesielska, Vivek Sudhakar, Lluis Samaranch, Philip Pivirotto, John Bringas, Catherine O'Riordan, Bryan Mastis, Waldy San Sebastian, John Forsayeth, Seng H Cheng, Krystof S Bankiewicz, Lamya S Shihabuddin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 3, Iss C (2016)
Huntington's disease (HD) is caused by a toxic gain-of-function associated with the expression of the mutant huntingtin (htt) protein. Therefore, the use of RNA interference to inhibit Htt expression could represent a disease-modifying therapy. The p
Externí odkaz:
https://doaj.org/article/43ac05468e3949adbb6afe92f17bbcd0
Autor:
Manish K. Aghi, Aaron Gallagher, Daniel Cummins, Michael W. McDermott, Vivek Sudhakar, Satvir Saggi, Miguel M. Chavez, Jason E. Chung, Steve Braunstein, Lauro N. Avalos, Mariza Daras, Philip V. Theodosopoulos, Ramin A. Morshed
Publikováno v:
World Neurosurgery. 158:e323-e333
Although overall survival (OS) has improved in patients with brain metastases (BMs), control of recurrent BMs remains a therapeutic challenge. Salvage surgery may achieve acceptable control rates in the setting of progression after previous stereotac
Autor:
Ramin A. Morshed, Jacob S. Young, Andrew J. Gogos, Alexander F. Haddad, James T. McMahon, Annette M. Molinaro, Vivek Sudhakar, Nadeem Al-Adli, Shawn L. Hervey-Jumper, Mitchel S. Berger
Publikováno v:
Acta neurochirurgica, vol 164, iss 2
Background There is a concern that glioma patients undergoing repeat craniotomies are more prone to complications. The study’s goal was to assess if the complication profiles for initial and repeat craniotomies were similar, to determine predictors
Autor:
Ramin A. Morshed, Jason E. Chung, Daniel D. Cummins, Vivek Sudhakar, Jacob S. Young, Mariza Daras, Shawn L. Hervey-Jumper, Philip V. Theodosopoulos, Manish K. Aghi
Publikováno v:
World neurosurgery. 162
Despite reports on the efficacy of checkpoint inhibitor (CPI) immunotherapies for metastatic cancers, there are limited data on the effectiveness of surgery for brain metastases (BMs) that have progressed after previous CPI treatment. We sought to ev
Autor:
Joseph H. Garcia, Ramin A. Morshed, Jason Chung, Miguel A. Millares Chavez, Vivek Sudhakar, Satvir Saggi, Lauro N. Avalos, Aaron Gallagher, Jacob S. Young, Mariza Daras, Michael W. McDermott, Paul A. Garcia, Edward F. Chang, Manish K. Aghi
Publikováno v:
Journal of neurosurgery. 138(1)
OBJECTIVE Epileptic seizures are a common and potentially devastating complication of metastatic brain tumors. Although tumor-related seizures have been described in previous case series, most studies have focused on primary brain tumors and have not
Autor:
Vivek Sudhakar, Raymond F. Sekula
Publikováno v:
British journal of neurosurgery.
Individuals with osteogenesis imperfecta develop pathologic bone due to genetic defects in collagen synthesis. These patients are prone to skull base abnormalities with resultant lower cranial nerve deficits, most common of which is trigeminal neural
Autor:
Lluis Samaranch, John Forsayeth, Waldy San Sebastian, Krystof S. Bankiewicz, Ernesto A. Salegio, Philip C. Allen, Piotr Hadaczek, Haifeng Chen, Michael V. Campagna, Jerusha Naidoo, Granger G.C. Hwa, Kousaku Ohno, John Bringas, Vivek Sudhakar, Diane E. Stockinger, Christopher Snieckus
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss, Pp 47-54 (2019)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
Here we evaluated the utility of MRI to monitor intrathecal infusions in nonhuman primates. Adeno-associated virus (AAV) spiked with gadoteridol, a gadolinium-based MRI contrast agent, enabled real-time visualization of infusions delivered either via
Autor:
Vivek Sudhakar, Shawn L. Hervey-Jumper, Jason E. Chung, Jacob S. Young, Manish K. Aghi, Ramin A. Morshed, Daniel Cummins, Philip V. Theodosopoulos
Publikováno v:
Neuro-oncology Advances
Background Despite the promising results for treating metastatic cancer with checkpoint inhibitor immunotherapies, there are limited data on surgical outcomes for brain metastases (BMs) that have progressed after prior checkpoint inhibitor treatment.
Autor:
Ramin Morshed, Ramin A Morshed, Jason Chung, Vivek Sudhakar, Daniel Cummins, Jacob S Young, Mariza Daras, Manish K Aghi
Publikováno v:
Neurosurgery. 67