Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vivek S. Tomar"'
Autor:
Mathew Thakur, Vivek S. Tomar, Emma Dale, Leonard G. Gomella, Charalambos Solomides, Oleksandr Kolesnikov, Scott W. Keith, Hector T. Navarro, Olivia Dahlgren, Michael Chaga, Edouard J. Trabulsi
Publikováno v:
BJUI Compass, Vol 5, Iss 7, Pp 675-680 (2024)
Abstract Objectives The objective of this study is to validate a hypothesis that a non‐invasive optical imaging assay targeting genomic VPAC receptors on malignant cells shed in voided urine will represent either benign prostatic hyperplasia (BPH)
Externí odkaz:
https://doaj.org/article/eba6f254466f4e338bfd77aa902133bd
Autor:
Zhen Lu, Jinyun Chen, Pengfei Yu, Matthew J. Atherton, Jun Gui, Vivek S. Tomar, Justin D. Middleton, Neil T. Sullivan, Sunil Singhal, Subin S. George, Ashley G. Woolfork, Aalim M. Weljie, Tsonwin Hai, Evgeniy B. Eruslanov, Serge Y. Fuchs
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Dendritic cells (DC) present tumour antigens to T cells but this process is defective in the tumour microenvironment. Here the authors find that downregulation of cholesterol 25-hydroxylase underlies defective cross presentation of tumour antigens.
Externí odkaz:
https://doaj.org/article/6f99c246674341cbadfcbbf971df3ad6
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Supplementary Tables 1, 2, and 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546bad13fd141f8f1defa7dae784bf9e
https://doi.org/10.1158/2326-6066.22545902
https://doi.org/10.1158/2326-6066.22545902
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Fragility of regulatory T (Treg) cells manifested by the loss of neuropilin-1 (NRP1) and expression of IFNγ undermines the immune suppressive functions of Treg cells and contributes to the success of immune therapies against cancers. Intratumoral Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5b2160ed088e90c87fe5fb79aaab1bd
https://doi.org/10.1158/2326-6066.c.6551048.v1
https://doi.org/10.1158/2326-6066.c.6551048.v1
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Supplementary Figure from Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569162bd4707629449e8049aabe81276
https://doi.org/10.1158/2326-6066.22545905
https://doi.org/10.1158/2326-6066.22545905
Autor:
Serge Y. Fuchs, Dmitry I. Gabrilovich, Yulia Nefedova, Allison Berger, Gurpanna Saggu, Jose R. Conejo-Garcia, M. Andres Blanco, Daniel P. Beiting, Tara Lee Costich, Noreen McBrearty, Jun Gui, Fangxue Yan, Raghavendra Basavaraja, Jinyang Li, Vivek S. Tomar, Hongru Zhang
Supplementary Data from Protection of Regulatory T Cells from Fragility and Inactivation in the Tumor Microenvironment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03ebcb7cdb23f17e6ced8aaf06d2b8c0
https://doi.org/10.1158/2326-6066.22545911.v1
https://doi.org/10.1158/2326-6066.22545911.v1
Autor:
Hongru Zhang, Pengfei Yu, Vivek S. Tomar, Xiangjie Chen, Matthew J. Atherton, Zhen Lu, Hong-Guang Zhang, Shifeng Li, Angelica Ortiz, Jun Gui, N. Adrian Leu, Fangxue Yan, Andres Blanco, Mirella L. Meyer-Ficca, Ralph G. Meyer, Daniel P. Beiting, Jinyang Li, Selene Nunez-Cruz, Roddy S. O’Connor, Lexus R. Johnson, Andy J. Minn, Subin S. George, Constantinos Koumenis, J. Alan Diehl, Michael C. Milone, Hui Zheng, Serge Y. Fuchs
Publikováno v:
Nature Cancer. 3:808-820
Evasion of antitumor immunity and resistance to therapies in solid tumors are aided by an immunosuppressive tumor microenvironment (TME). We found that TME factors, such as regulatory T cells and adenosine, downregulated type I interferon receptor IF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793f8f3111abf6cd7b393f81929de46e
https://doi.org/10.1038/s43018-022-00383-0
https://doi.org/10.1038/s43018-022-00383-0
Autor:
Hongru Zhang, Vivek S. Tomar, Jinyang Li, Raghavendra Basavaraja, Fangxue Yan, Jun Gui, Noreen McBrearty, Tara Lee Costich, Daniel P. Beiting, M. Andres Blanco, Jose R. Conejo-Garcia, Gurpanna Saggu, Allison Berger, Yulia Nefedova, Dmitry I. Gabrilovich, Serge Y. Fuchs
Publikováno v:
Cancer Immunol Res
Fragility of regulatory T (Treg) cells manifested by the loss of neuropilin-1 (NRP1) and expression of IFNγ undermines the immune suppressive functions of Treg cells and contributes to the success of immune therapies against cancers. Intratumoral Tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a20922e070b73ffc8481106619e1a90b
https://europepmc.org/articles/PMC9722544/
https://europepmc.org/articles/PMC9722544/
Autor:
Zhen Lu, Noreen McBrearty, Jinyun Chen, Vivek S. Tomar, Hongru Zhang, Gianluca De Rosa, Aiwen Tan, Aalim M. Weljie, Daniel P. Beiting, Zhen Miao, Subin S. George, Allison Berger, Gurpanna Saggu, J. Alan Diehl, Constantinos Koumenis, Serge Y. Fuchs
Publikováno v:
Cell Metabolism. 34:1342-1358.e7
Effector trogocytosis between malignant cells and tumor-specific cytotoxic T lymphocytes (CTLs) contributes to immune evasion through antigen loss on target cells and fratricide of antigen-experienced CTLs by other CTLs. The mechanisms regulating the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a66b1c0db493c175cf57d295d9fa5cc5
https://doi.org/10.1016/j.cmet.2022.08.007
https://doi.org/10.1016/j.cmet.2022.08.007