Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Vivek Das"'
Autor:
Alban Obel Slabowska, Charles Pyke, Henning Hvid, Leon Eyrich Jessen, Simon Baumgart, Vivek Das
Publikováno v:
Frontiers in Bioinformatics, Vol 4 (2024)
A major challenge in sequencing-based spatial transcriptomics (ST) is resolution limitations. Tissue sections are divided into hundreds of thousands of spots, where each spot invariably contains a mixture of cell types. Methods have been developed to
Externí odkaz:
https://doaj.org/article/bc6e0d7690d643888bd07dbe3cc4eb46
Autor:
Jaime Moreno, Lise Lotte Gluud, Elisabeth D Galsgaard, Henning Hvid, Gianluca Mazzoni, Vivek Das
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302853 (2024)
BackgroundChronic Kidney Disease (CKD) and Metabolic dysfunction-associated steatohepatitis (MASH) are metabolic fibroinflammatory diseases. Combining single-cell (scRNAseq) and spatial transcriptomics (ST) could give unprecedented molecular disease
Externí odkaz:
https://doaj.org/article/110996befe404f2b8fc3f222e410c0c1
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Multi-omics studies have enabled us to understand the mechanistic drivers behind complex disease states and progressions, thereby providing novel and actionable biological insights into health status. However, integrating data from multiple modalitie
Externí odkaz:
https://doaj.org/article/21aa6db75244468bae4e452295d31254
Autor:
Laura A. Cox, Jeannie Chan, Prahlad Rao, Zeeshan Hamid, Jeremy P. Glenn, Avinash Jadhav, Vivek Das, Genesio M. Karere, Ellen Quillen, Kylie Kavanagh, Michael Olivier
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Dietary high fructose (HFr) is a known metabolic disruptor contributing to development of obesity and diabetes in Western societies. Initial molecular changes from exposure to HFr on liver metabolism may be essential to understand
Externí odkaz:
https://doaj.org/article/027e176990914d9fa4b758efaea0c266
Publikováno v:
AIP Advances, Vol 12, Iss 8, Pp 085024-085024-19 (2022)
Among many smart materials, piezoelectric materials have emerged as the most studied ones for practical applications. They owe their success to several factors, including low price, high bandwidth, availability in various formats, and ease of handlin
Externí odkaz:
https://doaj.org/article/fcd1393cd51643e9b2f2a451adcebb9b
Autor:
Serena Buontempo, Pasquale Laise, James M. Hughes, Sebastiano Trattaro, Vivek Das, Chantal Rencurel, Giuseppe Testa
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
The Polycomb Repressive Complex 2 (PRC2) plays important roles in the epigenetic regulation of cellular development and differentiation through H3K27me3-dependent transcriptional repression. Aberrant PRC2 activity has been associated with cancer and
Externí odkaz:
https://doaj.org/article/364545fc5725480b9422d154b7645c28
Autor:
Pietro Lo Riso, Carlo Emanuele Villa, Gilles Gasparoni, Andrea Vingiani, Raffaele Luongo, Anna Manfredi, Annemarie Jungmann, Alessia Bertolotti, Francesca Borgo, Annalisa Garbi, Michela Lupia, Pasquale Laise, Vivek Das, Giancarlo Pruneri, Giuseppe Viale, Nicoletta Colombo, Teresa Manzo, Luigi Nezi, Ugo Cavallaro, Davide Cacchiarelli, Jörn Walter, Giuseppe Testa
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-20 (2020)
Abstract Background High-grade serous ovarian cancer (HGSOC) is a major unmet need in oncology. The remaining uncertainty on its originating tissue has hampered the discovery of molecular oncogenic pathways and the development of effective therapies.
Externí odkaz:
https://doaj.org/article/aa3c17c5bc5549b2bf586e26c47db96e
Publikováno v:
Frontiers in Genetics, Vol 11 (2020)
Multi-omics, variously called integrated omics, pan-omics, and trans-omics, aims to combine two or more omics data sets to aid in data analysis, visualization and interpretation to determine the mechanism of a biological process. Multi-omics efforts
Externí odkaz:
https://doaj.org/article/f149393bb67c493ab419e7506b30dad9
Publikováno v:
Applied Intelligence. 53:1287-1305
Autor:
Vivek Das, Firasat Hussain
Publikováno v:
ChemistrySelect. 8