Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Vivek Bhaskaran"'
Autor:
Vivek Bhaskaran, Michal O. Nowicki, Mahmoud Idriss, Miguel A. Jimenez, Gianmarco Lugli, Josie L. Hayes, Ahmad Bakur Mahmoud, Rachel E. Zane, Carmela Passaro, Keith L. Ligon, Daphne Haas-Kogan, Agnieszka Bronisz, Jakub Godlewski, Sean E. Lawler, E. Antonio Chiocca, Pierpaolo Peruzzi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
The delivery of single therapeutic microRNAs in brain cancers is challenging. Here, the authors engineer three neuronal microRNAs (miR-124, 128 and 137) into a cluster that, targeting oncogenic chromatin repressors, increases survival of GBM-bearing
Externí odkaz:
https://doaj.org/article/9eb6fe5b852d43329fafc6511460a696
Autor:
Pierpaolo Peruzzi, Vivek Bhaskaran
Publikováno v:
Journal of Experimental Neuroscience, Vol 13 (2019)
Much is known about microRNA biology and their involvement in essentially any biological processes in eukaryotic cells, including cancer. Now, to take advantage of them in clinics, a change in perspective is needed and a reappraisal of their features
Externí odkaz:
https://doaj.org/article/3ad35ba330e943d1bb629e5f86627145
Autor:
Hiroshi Nakashima, E. Antonio Chiocca, Gordon J. Freeman, David A. Reardon, Soledad Fernandez, Eric McLaughlin, William Goins, Maria C. Speranza, Khalid Shah, Sean E. Lawler, Marco Mineo, Vivek Bhaskaran, Hirotaka Ito, Korneel Grauwet, John McNulty, Isabel DeLaura, Quazim Alayo, Carmela Passaro
Engineering of NG34 to insert the sequence of the scFv against PD-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e2f6df88f5544728300b140b16c669e
https://doi.org/10.1158/1078-0432.22475267
https://doi.org/10.1158/1078-0432.22475267
Autor:
Hiroshi Nakashima, E. Antonio Chiocca, Gordon J. Freeman, David A. Reardon, Soledad Fernandez, Eric McLaughlin, William Goins, Maria C. Speranza, Khalid Shah, Sean E. Lawler, Marco Mineo, Vivek Bhaskaran, Hirotaka Ito, Korneel Grauwet, John McNulty, Isabel DeLaura, Quazim Alayo, Carmela Passaro
Supplementary figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43c1a6b2fd828ce94916f433e6f4dfd9
https://doi.org/10.1158/1078-0432.22475273
https://doi.org/10.1158/1078-0432.22475273
Autor:
Hiroshi Nakashima, E. Antonio Chiocca, Gordon J. Freeman, David A. Reardon, Soledad Fernandez, Eric McLaughlin, William Goins, Maria C. Speranza, Khalid Shah, Sean E. Lawler, Marco Mineo, Vivek Bhaskaran, Hirotaka Ito, Korneel Grauwet, John McNulty, Isabel DeLaura, Quazim Alayo, Carmela Passaro
Purpose:Glioblastoma (GBM) is resistant to standard of care. Immune checkpoints inhibitors (such as anti-PD-1 mAbs) efficiently restore antitumor T-cell activity. We engineered a new oncolytic herpes simplex virus (oHSV) expressing a single-chain ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4b1ee752b88d9f9a182a7dbf85d3bd
https://doi.org/10.1158/1078-0432.c.6529028
https://doi.org/10.1158/1078-0432.c.6529028
Autor:
Hiroshi Nakashima, E. Antonio Chiocca, Gordon J. Freeman, David A. Reardon, Soledad Fernandez, Eric McLaughlin, William Goins, Maria C. Speranza, Khalid Shah, Sean E. Lawler, Marco Mineo, Vivek Bhaskaran, Hirotaka Ito, Korneel Grauwet, John McNulty, Isabel DeLaura, Quazim Alayo, Carmela Passaro
Purification of the scFvPD-1 from HEK293 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528ae7d3efcd50ea9d4b9316cefe48a0
https://doi.org/10.1158/1078-0432.22475270.v1
https://doi.org/10.1158/1078-0432.22475270.v1
Autor:
Hiroshi Nakashima, E. Antonio Chiocca, Gordon J. Freeman, David A. Reardon, Soledad Fernandez, Eric McLaughlin, William Goins, Maria C. Speranza, Khalid Shah, Sean E. Lawler, Marco Mineo, Vivek Bhaskaran, Hirotaka Ito, Korneel Grauwet, John McNulty, Isabel DeLaura, Quazim Alayo, Carmela Passaro
In vivo comparison of scFvPD-1 production and viral gene expression in mouse and human GBM cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df507d006815aafedcbb484b2bf7706
https://doi.org/10.1158/1078-0432.22475264.v1
https://doi.org/10.1158/1078-0432.22475264.v1
Autor:
Mariano S. Viapiano, E. Antonio Chiocca, Diego J. Rodriguez-Gil, Sadhak Sengupta, Lina M. Barrera-Arenas, Sharon L. Longo, Vivek Bhaskaran, Prajna Behera, Mohan S. Nandhu
Legends of Figs S1 to S8, unmarked version
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636cb8e181fc57e3866f26484b09934c
https://doi.org/10.1158/1078-0432.22464189.v1
https://doi.org/10.1158/1078-0432.22464189.v1
Autor:
Mariano S. Viapiano, E. Antonio Chiocca, Diego J. Rodriguez-Gil, Sadhak Sengupta, Lina M. Barrera-Arenas, Sharon L. Longo, Vivek Bhaskaran, Prajna Behera, Mohan S. Nandhu
Supplemental Table I: Antibodies used for Western blotting and immunohistochemistry (IHC); Supplemental Table II: Sequences used for qRT-PCR primers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57a23b02d6931e76da93c5aa263b9fda
https://doi.org/10.1158/1078-0432.22464186
https://doi.org/10.1158/1078-0432.22464186
Autor:
Mariano S. Viapiano, E. Antonio Chiocca, Diego J. Rodriguez-Gil, Sadhak Sengupta, Lina M. Barrera-Arenas, Sharon L. Longo, Vivek Bhaskaran, Prajna Behera, Mohan S. Nandhu
Figure S1: Generation of mAb428.2 antibody; Figure S2: Affinity of mAb428.2 for fibulin-3; Figure S3: mAb428.2 binds to cell-surface and interstitial fibulin-3; Figure S4: mAb428.2 does not cause acute toxicity; Figure S5: Locally-delivered mAb428.2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48dc2f9a3e5578f8da0db8a9ecc24189
https://doi.org/10.1158/1078-0432.22464192
https://doi.org/10.1158/1078-0432.22464192