Asymmetric Synthesis of β,β-Disubstituted Alanines via a Sequential C(sp ² )-C(sp ³ ) Cross-Coupling-Hydrogenation Strategy.

Autor: Petrone DA; Department of Process Research & Development, Merck & Co., Inc., MRL, Rahway, New Jersey 07065, United States., Maturano J; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States., Herbort J; Department of Process Research & Development, Merck & Co., Inc., MRL, Rahway, New Jersey 07065, United States., Plasek EE; Department of Process Research & Development, Merck & Co., Inc., MRL, Rahway, New Jersey 07065, United States., Vivaldo-Nikitovic JM; Department of Process Research & Development, Merck & Co., Inc., MRL, Rahway, New Jersey 07065, United States., Sarlah D; Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.

Publikováno v: Organic letters [Org Lett] 2024 Jul 26; Vol. 26 (29), pp. 6284-6289. Date of Electronic Publication: 2024 Jul 11.