Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Vitukudi Narayanaiyengar Balaji"'
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 85:979-1001
We have presented an extensive analysis of the peptide backbone dihedral angles in the PDB structures and computed experimental Ramachandran plots for their distributions seen under a various constraints on X-ray resolution, representativeness at dif
Publikováno v:
Journal of Molecular Structure. 1108:352-369
Factor XIa inhibitors have been identified to have potential as anticoagulants with robust efficacy and low bleeding risks. In light of their significance and the availability of their 3-D X-ray data in the PDB, we present molecular docking studies c
Autor:
Raghuraman Kannan, Cory E. Johnson, Richard D. Hammer, Charles W. Caldwell, Govardhan A. Balaji, Vitukudi Narayanaiyengar Balaji
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Blocking the interaction between Programmed Death Ligand 1 (PD-L1) and its receptor, PD-1, is an effective method of treating many types of cancers. Certain tumors overexpress PD-L1, causing host immune cells that express PD-1 to bind PD-L1 and cease
Publikováno v:
Journal of Molecular Structure. 1042:86-103
We present molecular docking and 3-D QSAR studies on a series of tetrahydropyrimid-2-one HIV-1 protease inhibitors whose binding affinities to the enzyme span nearly 6 orders of magnitude. The docking investigations have been carried out with Surflex
Autor:
Shashidhar N. Rao, Kalyanaraman Ramnarayan, Vitukudi Narayanaiyengar Balaji, Salvatore Profeta, Ming Fai Chan
Publikováno v:
International Journal of Peptide and Protein Research. 45:366-376
As a part of the development of conformational guidelines for the design of metabolically altered peptidomimetics, we present conformational energy calculations on model dipeptide compounds with glycine (Gly), L-alanine (Ala), alpha-aminoisobutyric a
Publikováno v:
Bulletin of the Chemical Society of Japan. 70:293-299
Peptides with conformationally restricted 1-aminocyclopropane-1-carboxylic acid (Acc3) moieties were previously shown to exhibit preference for γ-turn structures in the solution phase and solid phase. We present conformational energy calculations on
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 49(2)
As a part of our studies on the structure and conformations of peptidomimetics, we present conformational energy calculations on model peptides with (a) diphenyl alanine and its tricyclic derivatives and (b) triphenyl alanine residues using molecular
Publikováno v:
Peptides ISBN: 9781461581789
Peptides are one of the most widely studied classes of compounds in the course of drug discovery. A number of endogenous peptides (e.g., endorphins and enkephalins) have been recognized as vital biological effectors such as hormones and neurotransmit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a7d20950102618c99f9a125a1d330b1
https://doi.org/10.1007/978-1-4615-8176-5_11
https://doi.org/10.1007/978-1-4615-8176-5_11
Publikováno v:
Peptides ISBN: 9789401090629
Peptides
Peptides
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc2d876b3b1bba80f3122361f8156881
https://doi.org/10.1007/978-94-010-9060-5_211
https://doi.org/10.1007/978-94-010-9060-5_211