Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Vittorio Zecchi"'
Publikováno v:
Journal of Inclusion Phenomena and Macrocyclic Chemistry. 71:129-136
Oral administration of indomethacin as well as drugs with low aqueous solubility usually results in poor absorption and bioavailability. The aim of this study was to prepare enteric-coated bovine serum albumin nanospheres carrying cyclodextrin comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9275d05b7df3cb3e074d55d6358d465
https://doi.org/10.1007/s10847-010-9916-z
https://doi.org/10.1007/s10847-010-9916-z
Publikováno v:
Archiv der Pharmazie. 324:943-947
We describe a method to determine the affinity constant values between Ketoprofen and β-cyclodextrin and hydroxypropyl-β-cyclodextrin in semisolid vehicles. The method is based on the diffusion of the drug, released from semisolid vehicles, through
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b35c7a1bbae9e7e6f6e1e0bfa0d5ec60
https://doi.org/10.1002/ardp.2503241201
https://doi.org/10.1002/ardp.2503241201
Publikováno v:
Expert Opinion on Drug Delivery. 7:811-828
Importance of the field: Chitosan represents a multifunctional polymer, featuring both mucoadhesive and permeation-enhancing properties and therefore is a widely studied excipient for mucosal drug delivery. As regards nasal administration, chitosans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0da25aaeab91b59e88a348190cf8bd2
https://doi.org/10.1517/17425247.2010.495981
https://doi.org/10.1517/17425247.2010.495981
Autor:
Vittorio Zecchi, Milena Sorrenti, Federica Bigucci, Barbara Luppi, Laura Mercolini, Laura Catenacci, Alessandro Musenga
Publikováno v:
Journal of Pharmacy and Pharmacology. 61:151-157
Objectives The purpose of this study was the preparation and characterisation of mucoadhesive nasal inserts based on chitosan/hyaluronate polyelectrolyte complexes prepared at various pHs and at different molar ratios. Methods A suspension of chitosa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ecb7a0c848292d3d702b77053138010
https://doi.org/10.1211/jpp.61.02.0003
https://doi.org/10.1211/jpp.61.02.0003
Determination of insulin in innovative formulations by means of LC coupled to fluorescence detection
Autor:
Bruno Saladini, Alessandro Musenga, Vittorio Zecchi, Barbara Luppi, Laura Mercolini, Maria Augusta Raggi, Federica Bigucci
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 48:1303-1309
A fast and simple method based on LC with fluorescence detection has been developed for the determination of insulin in innovative formulations consisting of microparticles and inserts for oral and nasal drug administration, respectively. A reverse-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1e5f453fcc6719acd4ccf09c42545a3
https://doi.org/10.1016/j.jpba.2008.09.009
https://doi.org/10.1016/j.jpba.2008.09.009
Autor:
Vittorio Zecchi, Barbara Luppi, Roberto Mandrioli, Maria Augusta Raggi, Alessandro Musenga, Salvatore Fanali
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 42:32-38
A new fast capillary electrophoretic method has been developed for the analysis of the glycopeptide antibiotic vancomycin in formulations. An electrophoretic run is completed within 3.0 min; fused silica capillaries (100 μm i.d., 8.5 cm effective le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d39ea5e2aced23f92470225fc5fbad6
https://doi.org/10.1016/j.jpba.2005.11.022
https://doi.org/10.1016/j.jpba.2005.11.022
Publikováno v:
International Journal of Pharmaceutics. 258:209-215
An inclusion complex composed of progesterone (Prog) and hydroxypropyl-beta-cyclodextrin (HPbetaCD) was prepared by the spray-drying and freeze-drying methods. Prog alone and its inclusion complex with HPbetaCD were incorporated into chitosan by spra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7df5f79f97d0ab27c7b4de05fad3366
https://doi.org/10.1016/s0378-5173(03)00202-3
https://doi.org/10.1016/s0378-5173(03)00202-3
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 55:199-202
Delivery of drugs to the large bowel has been extensively investigated during the last decade. The aim of this work was to study polymethacrylic acid-co-methylmethacrylate substituted with fatty acids (lauric, myristic, palmitic and stearic) at 20% s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a343792aad43b0699bfc5c4ce388c0c5
https://doi.org/10.1016/s0939-6411(02)00190-x
https://doi.org/10.1016/s0939-6411(02)00190-x
Autor:
Federica Bigucci, Barbara Luppi, Vittorio Zecchi, A.M. Di Pietra, Isabella Orienti, Teresa Cerchiara
Publikováno v:
Drug Delivery. 10:239-244
Poly(methyl vinyl ether-co-maleic anhydride) crosslinked with ethylene glycol (GZ-ET), 1,4-butanediol (GZ-BUT), 1,6-exandiol (GZ-EX), 1,8-octanediol (GZ-OCT), 1,10-decanediol (GZ-DEC) or 1,12-dodecanediol (GZ-DOD) was prepared and employed as a suppo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bff6de498b572a4ce5cd2531f91ab8
https://doi.org/10.1080/drd_10_4_239
https://doi.org/10.1080/drd_10_4_239
Autor:
Giuseppe Corace, Vittorio Zecchi, Barbara Luppi, Teresa Cerchiara, Federica Bigucci, Angela Abruzzo
The objective of this investigation was the development of chitosan/pectin based nasal inserts to improve bioavailability of antipsychotic drugs in the treatment of psychotic symptoms. In fact, the nasal route of administration ensures systemic avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a41a00236512ac7490010a81187ecb
http://hdl.handle.net/11585/90533
http://hdl.handle.net/11585/90533
