Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Vittorio Necchi"'
Autor:
Daniela Montagna, Patrizia Sommi, Vittorio Necchi, Agostina Vitali, Enrica Montini, Ilaria Turin, Daniela Ferraro, Vittorio Ricci, Enrico Solcia
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Two types of polyubiquitin-reactive cytoplasmic bodies, particulate cytoplasmic structures (PaCS) and dendritic cell (DC) aggresome-like induced structures (DALIS), were analyzed by electron microscopy, immunocytochemistry, immunoblotting, a
Externí odkaz:
https://doaj.org/article/76cc33c296a74313bcbe626534d77a3c
Publikováno v:
Toxins, Vol 11, Iss 11, p 618 (2019)
A key role in the carcinogenic action of Helicobacter pylori is played by the effector protein CagA, the first identified oncoprotein of the bacterial world. However, the present knowledge in regard to the bacterial injection of CagA into epithelial
Externí odkaz:
https://doaj.org/article/7268fed8eaa04ebf8b88712c1593ee2a
Autor:
Enrico Solcia, Patrizia Sommi, Vittorio Necchi, Agostina Vitali, Rachele Manca, Vittorio Ricci
Publikováno v:
Biomolecules, Vol 4, Iss 3, Pp 848-861 (2014)
Cytoplasmic structures showing a selective concentration of both polyubiquitinated proteins and proteasome have been described in various epithelial, hematopoietic, mesenchymal and neural cells in vitro or in fetal tissues, as well as in chronically-
Externí odkaz:
https://doaj.org/article/d0d0abc09f6e477fad7a76d27089807d
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2767 (2018)
In this article, we outline and discuss available information on the cellular site and mechanism of proteasome interaction with cytosolic polyubiquitinated proteins and heat-shock molecules. The particulate cytoplasmic structure (PaCS) formed by barr
Externí odkaz:
https://doaj.org/article/6e73f0e3cd004fd5994b83150a2748b2
Autor:
Patrizia Sommi, Vittorio Necchi, Agostina Vitali, Daniela Montagna, Ada De Luigi, Mario Salmona, Vittorio Ricci, Enrico Solcia
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82560 (2013)
A variety of ubiquitinated protein-containing cytoplasmic structures has been reported, from aggresomes to aggresome-like induced structures/sequestosomes or particle-rich cytoplasmic structures (PaCSs) that we recently observed in some human disease
Externí odkaz:
https://doaj.org/article/b351f285a344414297f0c014847e3539
Autor:
Vittorio Necchi, Antonella Minelli, Patrizia Sommi, Agostina Vitali, Roberta Caruso, Daniela Longoni, Maria Rita Frau, Cristina Nasi, Fabiola De Gregorio, Marco Zecca, Vittorio Ricci, Cesare Danesino, Enrico Solcia
Publikováno v:
Haematologica, Vol 97, Iss 7 (2012)
Background Shwachman–Diamond syndrome is an autosomal recessive disorder in which severe bone marrow dysfunction causes neutropenia and an increased risk of leukemia. Recently, novel particulate cytoplasmic structures, rich in ubiquitinated and pro
Externí odkaz:
https://doaj.org/article/dfcac8c03ba64673b7b45ef1c4bd2ccf
Autor:
Vittorio Necchi, Patrizia Sommi, Alessandro Vanoli, Rachele Manca, Vittorio Ricci, Enrico Solcia
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21317 (2011)
A novel cytoplasmic structure has been recently characterized by confocal and electron microscopy in H. pylori-infected human gastric epithelium, as an accumulation of barrel-like proteasome reactive particles colocalized with polyubiquitinated prote
Externí odkaz:
https://doaj.org/article/54efb44b84c0429293141b263c60e14b
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9716 (2010)
Cell internalization and intracellular fate of H. pylori products/virulence factors in vivo by human gastric epithelium, the main target of H. pylori-induced pathologies (i.e., peptic ulcer and cancer), are still largely unknown. Investigating gastri
Externí odkaz:
https://doaj.org/article/84218e75121d43419f85ae5092285172
Autor:
Vittorio Ricci, Patrizia Sommi, Ilaria Turin, Enrica Montini, Agostina Vitali, Vittorio Necchi, Daniela Montagna, Daniela Ferraro, Enrico Solcia
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Two types of polyubiquitin-reactive cytoplasmic bodies, particulate cytoplasmic structures (PaCS) and dendritic cell (DC) aggresome-like induced structures (DALIS), were analyzed by electron microscopy, immunocytochemistry, immunoblotting, and flow c
Autor:
Vittorio Necchi, Vittorio Ricci, Patrizia Sommi, Enrico Solcia, Alessandro Vanoli, Roberto Fiocca
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports
Scientific Reports
Uptake, intracellular trafficking and pathologic effects of VacA toxin from Helicobacter pylori have been widely investigated in vitro. However, no systematic analysis investigated VacA intracellular distribution and fate in H. pylori-infected human