Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Vittorio L Katis"'
Autor:
Yuhong Du, Dongxue Wang, Vittorio L. Katis, Elizabeth L. Zoeller, Min Qui, Allan I. Levey, Opher Gileadi, Haian Fu
Publikováno v:
SLAS Discovery, Vol 29, Iss 6, Pp 100177- (2024)
The spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) interaction has a major role in the normal innate and adaptive immune responses, but dysregulation of this interaction is implicated in several
Externí odkaz:
https://doaj.org/article/d8073c541d1c4808baf8ed2a88d5e137
Autor:
Jacob L. Capener, James D. Vasta, Vittorio L. Katis, Ani Michaud, Michael T. Beck, Sabrina C. D. Daglish, Sarit Cohen-Kedar, Efrat Shaham Barda, Stefanie Howell, Iris Dotan, Matthew B. Robers, Alison D. Axtman, Frances M. Bashore
Publikováno v:
Frontiers in Chemical Biology, Vol 3 (2024)
Spleen tyrosine kinase (SYK) is a non-receptor tyrosine kinase that is activated by phosphorylation events downstream of FcR, B-cell and T-cell receptors, integrins, and C-type lectin receptors. When the tandem Src homology 2 (SH2) domains of SYK bin
Externí odkaz:
https://doaj.org/article/5b14e25fb79449cd9a67529c673d86a8
Autor:
Frances M Bashore, Vittorio L Katis, Yuhong Du, Arunima Sikdar, Dongxue Wang, William J Bradshaw, Karolina A Rygiel, Tina M Leisner, Rod Chalk, Swati Mishra, C Andrew Williams, Opher Gileadi, Paul E Brennan, Jesse C Wiley, Jake Gockley, Gregory A Cary, Gregory W Carter, Jessica E Young, Kenneth H Pearce, Haian Fu, Emory-Sage-SGC TREAT-AD Center, Alison D Axtman
Publikováno v:
PLoS ONE, Vol 19, Iss 2, p e0293548 (2024)
RNA sequencing and genetic data support spleen tyrosine kinase (SYK) and high affinity immunoglobulin epsilon receptor subunit gamma (FCER1G) as putative targets to be modulated for Alzheimer's disease (AD) therapy. FCER1G is a component of Fc recept
Externí odkaz:
https://doaj.org/article/a694cd69ff044329bed258122700d8e8
Autor:
Jesse A. Coker, Vittorio L. Katis, Michael Fairhead, Anja Schwenzer, Stine B. Clemmensen, Bent U. Frandsen, Willem A. de Jongh, Opher Gileadi, Nicola A. Burgess-Brown, Brian D. Marsden, Kim S. Midwood, Wyatt W. Yue
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Recombinant protein expression in eukaryotic insect cells is a powerful approach for producing challenging targets. However, due to incompatibility with standard baculoviral platforms and existing low-throughput methodology, the use of the Drosophila
Externí odkaz:
https://doaj.org/article/b1a66327cf994b558e7f1cba4b4aa7bc
Autor:
Katsuhiko Shirahige, Vittorio L. Katis, Maurici B. Roig, Makiko Komata, Pelin Uluocak, Bin Hu, Takashi Sutani, Kim Nasmyth, Frédéric Beckouët
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2010, 39 (5), pp.689-699. ⟨10.1016/j.molcel.2010.08.008⟩
Molecular Cell, Elsevier, 2010, 39 (5), pp.689-699. ⟨10.1016/j.molcel.2010.08.008⟩
Sister chromatid cohesion is thought to involve entrapment of sister DNAs by a tripartite ring composed of the cohesin subunits Smc1, Smc3, and Scc1. Establishment of cohesion during S phase depends on acetylation of Smc3's nucleotide-binding domain
Autor:
Aliona Bogdanova, Jesse J. Lipp, Richard Imre, Karl Mechtler, Elwy Okaz, Bianca Habermann, Kim Nasmyth, Wolfgang Zachariae, Vittorio L. Katis
Publikováno v:
Scopus-Elsevier
Developmental Cell
Developmental Cell
Summary During meiosis, two rounds of chromosome segregation after a single round of DNA replication produce haploid gametes from diploid precursors. At meiosis I, maternal and paternal kinetochores are pulled toward opposite poles, and chiasmata hol
Autor:
Pelin Uluocak, Ajay Kumar Mishra, Tatsuya Nishino, Jean Metson, Benjamin D. Rowland, Vittorio L. Katis, Maurici B. Roig, Kim Nasmyth, Alexander Kurze, Richard Imre, Frédéric Beckouët, Karl Mechtler, Philippa Underwood
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2009, 33 (6), pp.763-774. ⟨10.1016/j.molcel.2009.02.028⟩
Molecular Cell, Elsevier, 2009, 33 (6), pp.763-774. ⟨10.1016/j.molcel.2009.02.028⟩
Cohesin's Smc1, Smc3, and Scc1 subunits form a tripartite ring that entraps sister DNAs. Scc3, Pds5, and Rad61 (Wapl) are regulatory subunits that control this process. We describe here smc3, scc3, pds5, and rad61 mutations that permit yeast cell pro
Publikováno v:
Cell. 117:471-482
At anaphase onset, the protease separase triggers chromosome segregation by cleaving the chromosomal cohesin complex. Here, we show that cohesin destruction in metaphase is sufficient for segregation of much of the budding yeast genome, but not of th
Autor:
Danny T. C. Huang, Richard I. Christopherson, Richard Wolfenden, R. Ian Menz, Feng Zhao, Vittorio L. Katis, Jacob Kaplan, R. Gerry Wake
Publikováno v:
Biochemistry. 45(27)
Dihydroorotase (DHOase, EC 3.5.2.3) from the extreme thermophile Bacillus caldolyticus has been subcloned, sequenced, expressed, and purified as a monomer. The catalytic properties of this thermophilic DHOase have been compared with another type I en
Autor:
Laurence Pelletier, Juraj Gregan, Frank Buchholz, Bulent Cetin, Takehiko Itoh, Egon Ogris, Katsuhiko Shirahige, Marta Galova, Vittorio L. Katis, Christian G. Riedel, Mark Petronczki, Karl Mechtler, Saori Mori, Yuki Katou, Ingrid Mudrak, Wolfgang Helmhart, Kim Nasmyth
Publikováno v:
Nature. 441(7089)
Segregation of homologous maternal and paternal centromeres to opposite poles during meiosis I depends on post-replicative crossing over between homologous non-sister chromatids, which creates chiasmata and therefore bivalent chromosomes. Destruction