Zobrazeno 1 - 10
of 348
pro vyhledávání: '"Vittorio Martinelli"'
Autor:
Davide De Federicis, Claudia Bassani, Rosaria Rita Chiarelli, Federico Montini, Antonino Giordano, Federica Esposito, Nilo Riva, Angelo Quattrini, Vittorio Martinelli, Massimo Filippi, Cinthia Farina
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Neurological disorders, including multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS), may be associated with alterations in blood cell composition and phenotype. Here, we focused our attention on circulating mucosal-associated invariant
Externí odkaz:
https://doaj.org/article/5284a7c32dda470db8b419159ba98497
Autor:
Daniele Avancini, Alessandro Testori, Lucia Fresolone, Grazia Andolfi, Michela Vuono, Vittorio Martinelli, Francesca R. Santoni de Sio, Silvia Gregori
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112193- (2023)
Summary: Interleukin (IL)-10 is a main player in peripheral immune tolerance, the physiological mechanism preventing immune reactions to self/harmless antigens. Here, we investigate IL-10-induced molecular mechanisms generating tolerogenic dendritic
Externí odkaz:
https://doaj.org/article/e31fc4378cdb4db3a5929ab27b176b5b
Autor:
Ferdinando Clarelli, Nadia Barizzone, Eleonora Mangano, Miriam Zuccalà, Chiara Basagni, Santosh Anand, Melissa Sorosina, Elisabetta Mascia, Silvia Santoro, PROGEMUS, PROGRESSO, Franca Rosa Guerini, Eleonora Virgilio, Antonio Gallo, Alessandro Pizzino, Cristoforo Comi, Vittorio Martinelli, Giancarlo Comi, Gianluca De Bellis, Maurizio Leone, Massimo Filippi, Federica Esposito, Roberta Bordoni, Filippo Martinelli Boneschi, Sandra D'Alfonso, P Crociani, D Vecchio, P Ragonese, A Gajofatto, E Scarpini, A Bertolotto, D Caputo, C Gasperini, F Granella, S Cordera, P Cavallo, R Cavallo, R Bergamaschi, G Ristori, C Solaro, F Martinelli, F Passantino, M Pugliatti, A Gallo, L Brambilla, C Clerico, F Capone, F Esposito, G Liberatore, M Rodegher, p Rossi, M Radaelli, L Moiola, B Colombo, A Ghezzi, A Annovazzi, R Capra, G Coniglio, M. P Amato, B Nacmias, G Tedeschi, A D’Ambrosio, P Cavalla, F Patti, E D’Amico, D Galimberti, P Gallo, M Atzori, L Grimaldi, S Bucello, G Mancardi, E Capello
Publikováno v:
Frontiers in Genetics, Vol 12 (2022)
Genome-wide association studies identified over 200 risk loci for multiple sclerosis (MS) focusing on common variants, which account for about 50% of disease heritability. The goal of this study was to investigate whether low-frequency and rare funct
Externí odkaz:
https://doaj.org/article/68d0393bd32c4e15a1437e3e4fc9a308
Autor:
Gabriel Siracusano, Annamaria Finardi, Claudia Pastori, Vittorio Martinelli, Roberto Furlan, Lucia Lopalco
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Recent studies showed that immunological tolerance may restrict the development of Env-specific autoreactive broadly neutralizing antibodies. This evidence is consistent with the finding that Env immunization of a systemic lupus erythematosus (SLE) m
Externí odkaz:
https://doaj.org/article/34502d4afc734c31a98121ecd06cfa5a
Autor:
Federico Montini, Agostino Nozzolillo, Paola M. V. Rancoita, Chiara Zanetta, Lucia Moiola, Federica Cugnata, Federica Esposito, Maria A. Rocca, Vittorio Martinelli, Massimo Filippi
Publikováno v:
Journal of Neurology. 270:1835-1842
Autor:
Massimo Acquaviva, Ramesh Menon, Marco Di Dario, Gloria Dalla Costa, Marzia Romeo, Francesca Sangalli, Bruno Colombo, Lucia Moiola, Vittorio Martinelli, Giancarlo Comi, Cinthia Farina
Publikováno v:
Cell Reports Medicine, Vol 1, Iss 4, Pp 100053- (2020)
Summary: Peripheral blood mononuclear cells (PBMCs) bear specific dysregulations in genes and pathways at distinct stages of multiple sclerosis (MS) that may help with classifying MS and non-MS subjects, specifying the early stage of disease, or disc
Externí odkaz:
https://doaj.org/article/82fb05d0943f4e909ce73f9f4350976e
Autor:
Sundararajan Srinivasan, Martina Severa, Fabiana Rizzo, Ramesh Menon, Elena Brini, Rosella Mechelli, Vittorio Martinelli, Paul Hertzog, Marco Salvetti, Roberto Furlan, Gianvito Martino, Giancarlo Comi, Eliana M. Coccia, Cinthia Farina
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Recent evidence indicates that single multiple sclerosis (MS) susceptibility genes involved in interferon (IFN) signaling display altered transcript levels in peripheral blood of untreated MS subjects, suggesting that responsiveness to endog
Externí odkaz:
https://doaj.org/article/5eca37b29ea3460fbd37602ded3bbfa2
Autor:
Miryam Cannizzaro, Laura Ferré, Ferdinando Clarelli, Antonino Giordano, Francesca Sangalli, Bruno Colombo, Giancarlo Comi, Lucia Moiola, Vittorio Martinelli, Massimo Filippi, Federica Esposito
Publikováno v:
Journal of Neurology. 269:5596-5605
Multiple sclerosis (MS) is a chronic autoimmune disease with huge heterogeneity in terms of clinical course, disease severity and treatment response. The need for a tailored treatment approach has emerged over the last few years. The present observat
Autor:
Massimo Acquaviva, Claudia Bassani, Nicole Sarno, Gloria Dalla Costa, Marzia Romeo, Francesca Sangalli, Bruno Colombo, Lucia Moiola, Vittorio Martinelli, Giancarlo Comi, Cinthia Farina
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Recent evidence suggests that the primary progressive form of multiple sclerosis (PP-MS) may present with specific immunological alterations. In this study we focused our attention on CD161, an NK and T cell marker upregulated in relapsing-remitting
Externí odkaz:
https://doaj.org/article/c7ef3bad3bf346a4b87d2660178b8c49
Autor:
Chiara Zanetta, Maria A. Rocca, Alessandro Meani, Vittorio Martinelli, Laura Ferrè, Lucia Moiola, Massimo Filippi
Publikováno v:
Journal of Neurology.