PARP-14 Promotes Survival of Mammalian α but Not β Pancreatic Cells Following Cytokine Treatment

Autor: Floriana D'Angeli, Marina Scalia, Matilde Cirnigliaro, Cristina Satriano, Vincenza Barresi, Nicolò Musso, Angela Trovato-Salinaro, Davide Barbagallo, Marco Ragusa, Cinzia Di Pietro, Michele Purrello, Vittoria Spina-Purrello

Publikováno v: Frontiers in Endocrinology, Vol 10 (2019)

PARP-14 (poly-ADP Ribose Polymerase-14), a member of the PARP family, belongs to the group of Bal proteins (B Aggressive Lymphoma). PARP-14 has recently appeared to be involved in the transduction pathway mediated by JNKs (c Jun N terminal Kinases),

Externí odkaz: https://doaj.org/article/c73a9e636ec04ee1aac1e513fc9a466c

CircSMARCA5 regulates VEGFA mRNA splicing and angiogenesis in glioblastoma multiforme through the binding of SRSF1

Autor: Antonio Morrone, Rosario Caltabiano, Vittoria Spina-Purrello, Cristina Barbagallo, Francesco Certo, Michele Purrello, Davide Barbagallo, Giuseppe Broggi, Marco Ragusa, Giovanni Lauretta, Duilia Brex, Giuseppe Barbagallo, Thomas B. Hansen, Angela Caponnetto, Federica Mirabella, Cinzia Di Pietro

Publikováno v: Barbagallo, D, Caponnetto, A, Brex, D, Mirabella, F, Barbagallo, C, Lauretta, G, Morrone, A, Certo, F, Broggi, G, Caltabiano, R, Barbagallo, G M, Spina-Purrello, V, Ragusa, M, Di Pietro, C, Hansen, T B & Purrello, M 2019, ' CircSMARCA5 regulates VEGFA mRNA splicing and angiogenesis in glioblastoma multiforme through the binding of SRSF1 ', Cancers, vol. 11, no. 2, 194 . https://doi.org/10.3390/cancers11020194
Cancers
Volume 11
Issue 2
Cancers, Vol 11, Iss 2, p 194 (2019)

Circular RNAs are a large group of RNAs whose cellular functions are still being investigated. We recently proposed that circSMARCA5 acts as sponge for the splicing factor Serine and Arginine Rich Splicing Factor 1 (SRSF1) in glioblastoma multiforme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8556bc4f7acec137b4a44607a7e4bfa
https://pure.au.dk/portal/da/publications/circsmarca5-regulates-vegfa-mrna-splicing-and-angiogenesis-in-glioblastoma-multiforme-through-the-binding-of-srsf1(f5e25cc3-fc91-42c4-b6b5-8542830f6475).html

The reproductive system at the neuroendocrine-immune interface: focus on LHRH, estrogens and growth factors in LHRH neuron–glial interactions

Autor: Giovanna M. Scoto, Roberto Avola, Francesco Gallo, Nuccio Testa, M. C. Morale, Bianca Marchetti, Salvatore Caniglia, Francesca L'Episcopo, Vittoria Spina-Purrello, Florinda Gennuso, Cataldo Tirolo

Publikováno v: Domestic Animal Endocrinology. 25:21-46

Bidirectional communication between the neuroendocrine and immune systems plays a pivotal role in health and disease. Signals generated by the hypothalamic–pituitary–gonadal (HPG) axis (i.e. luteinizing hormone-releasing hormone, LHRH, and sex st

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9412faf7a2ecebd84378a4147ea2d4
https://doi.org/10.1016/s0739-7240(03)00043-2

An in vitro retini blastoma human triple culture model of angiogenesis: A modulatory effect of TGF-β

Autor: Mario Alberghina, Vittoria Spina-Purrello, Gabriella Lupo, Mario Salmeri, Carla Motta, Carmelina Daniela Anfuso

Retinoblastoma is the most common intraocular tumour in children. In view of understanding the molecular mechanisms through which angiogenic switch on happens in the early phases of reciprocal interaction between tumour and cells constituting retinal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf6dfd2bf73aec32c3c9f4d07d8bd52
http://hdl.handle.net/20.500.11769/15542

Parp and cell death or protection in rat primary astroglial cell cultures under LPS/IFNgamma induced proinflammatory conditions

Autor: Anna Maria Giuffrida-Stella, V. G. Nicoletti, D. Patti, Vittoria Spina-Purrello

Publikováno v: Neurochemical research. 33(12)

The enzyme poly(ADP-ribose)polymerase (PARP) has a leader role in the DNA damage survey mechanisms by its nick-sensor function, but it is also involved in the early events of the programmed cell death, particularly during inflammatory injury, as a co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfe8aa835723c2cc1d2db83c9589a32b
https://pubmed.ncbi.nlm.nih.gov/18758954