Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vittoria Nanna"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 2398-2415 (2021)
SHP2 is a ubiquitous protein tyrosine phosphatase, whose activity is regulated by phosphotyrosine (pY)-containing peptides generated in response to extracellular stimuli. Its crystal structure reveals a closed, auto-inhibited conformation in which th
Externí odkaz:
https://doaj.org/article/ec15cb08fa044f438eafe0c8843478dd
Autor:
Naira Samarina, George Ssebyatika, Tanvi Tikla, Ja-Yun Waldmann, Bizunesh Abere, Vittoria Nanna, Michelangelo Marasco, Teresa Carlomagno, Thomas Krey, Thomas F Schulz
Publikováno v:
PLoS Pathogens, Vol 17, Iss 6, p e1009635 (2021)
Kaposi Sarcoma-associated herpesvirus (KSHV) causes three human malignancies, Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and the plasma cell variant of multicentric Castleman's Disease (MCD), as well as an inflammatory cytokine syndrome (KI
Externí odkaz:
https://doaj.org/article/5bd22e854467486fb7a9d993ffd4e8b5
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss, Pp 2398-2415 (2021)
Computational and Structural Biotechnology Journal
Computational and structural biotechnology journal
Netherlands
Computational and Structural Biotechnology Journal
Computational and structural biotechnology journal
Netherlands
Graphical abstract
SHP2 is a ubiquitous protein tyrosine phosphatase, whose activity is regulated by phosphotyrosine (pY)-containing peptides generated in response to extracellular stimuli. Its crystal structure reveals a closed, auto-inhibited
SHP2 is a ubiquitous protein tyrosine phosphatase, whose activity is regulated by phosphotyrosine (pY)-containing peptides generated in response to extracellular stimuli. Its crystal structure reveals a closed, auto-inhibited
Autor:
Sandra Johannsen, Robin M. Gierse, Arne Krüger, Rachel L. Edwards, Vittoria Nanna, Anna Fontana, Di Zhu, Tizina Masini, Lais Pessanha de Carvalho, Mael Poizat, Bart Kieftenbelt, Dana M. Hodge, Sophie Alvarez, Daan Bunt, Kamila Anna Meissner, Edmarcia Elisa de Souza, Melloney Dröge, Bernard van Vliet, Jack de Hartog, Michael C. Hutter, Jana Held, Audrey R. Odom John, Carsten Wrenger, Anna K. H. Hirsch
In this study, we identified three novel compound classes with potent activity against Plasmodium falciparum, the most dangerous human malarial parasite. Resistance of this pathogen to known drugs is increasing and compounds with different modes of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::968d2b347432557d44f960aef4313c60
https://doi.org/10.26434/chemrxiv-2022-npslc
https://doi.org/10.26434/chemrxiv-2022-npslc
Autor:
Bizunesh Abere, Thomas Krey, Naira Samarina, Teresa Carlomagno, Michelangelo Marasco, George Ssebyatika, Vittoria Nanna, Tanvi Tikla, Ja-Yun Waldmann, Thomas F. Schulz
Publikováno v:
PLoS pathogens 17(6), e1009635 (1-30) (2021). doi:10.1371/journal.ppat.1009635
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 6, p e1009635 (2021)
PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 6, p e1009635 (2021)
PLoS pathogens 17(6), e1009635 (1-30) (2021). doi:10.1371/journal.ppat.1009635
Kaposi Sarcoma-associated herpesvirus (KSHV) causes three human malignancies, Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and the plasma cell variant of mult
Kaposi Sarcoma-associated herpesvirus (KSHV) causes three human malignancies, Kaposi Sarcoma (KS), Primary Effusion Lymphoma (PEL) and the plasma cell variant of mult