Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Vittoria LOPEZ"'
Autor:
Vittoria Lopez, H. J. Maximilian Schuh, Salahuddin Mirza, Victoria J. Vaaßen, Michael S. Schmidt, Katharina Sylvester, Riham M. Idris, Christian Renn, Laura Schäkel, Julie Pelletier, Jean Sévigny, Annamaria Naggi, Björn Scheffler, Sang-Yong Lee, Gerd Bendas, Christa E. Müller
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionHeparins, naturally occurring glycosaminoglycans, are widely used for thrombosis prevention. Upon application as anticoagulants in cancer patients, heparins were found to possess additional antitumor activities. Ectonucleotidases have rec
Externí odkaz:
https://doaj.org/article/a4e6c471d88140e28ff18ae97091a960
Autor:
Julie Pelletier, Jean Sévigny, Laura Schäkel, Salahuddin Mirza, Riekje Winzer, Vittoria Lopez, Riham Idris, Haneen Al-Hroub, Eva Tolosa, Christa E Müller
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 8 (2022)
Background An important mechanism, by which cancer cells achieve immune escape, is the release of extracellular adenosine into their microenvironment. Adenosine activates adenosine A2A and A2B receptors on immune cells constituting one of the stronge
Externí odkaz:
https://doaj.org/article/8abf22ac4a1d4fadacc1d985d35a7a52
Autor:
Laura Schäkel, Constanze C. Schmies, Riham M. Idris, Xihuan Luo, Sang-Yong Lee, Vittoria Lopez, Salahuddin Mirza, The Hung Vu, Julie Pelletier, Jean Sévigny, Vigneshwaran Namasivayam, Christa E. Müller
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nucleoside triphosphate diphosphohydrolase1 (NTPDase1, CD39) inhibitors have potential as novel drugs for the (immuno)therapy of cancer. They increase the extracellular concentration of immunostimulatory ATP and reduce the formation of AMP, which can
Externí odkaz:
https://doaj.org/article/903114e2b7ec421aacb756b26bca55e7
Autor:
Vittoria Lopez, Laura Schäkel, H. J. Maximilian Schuh, Michael S. Schmidt, Salahuddin Mirza, Christian Renn, Julie Pelletier, Sang-Yong Lee, Jean Sévigny, Susanne Alban, Gerd Bendas, Christa E. Müller
Publikováno v:
Marine Drugs, Vol 19, Iss 2, p 51 (2021)
Extracellular ATP mediates proinflammatory and antiproliferative effects via activation of P2 nucleotide receptors. In contrast, its metabolite, the nucleoside adenosine, is strongly immunosuppressive and enhances tumor proliferation and metastasis.
Externí odkaz:
https://doaj.org/article/ad33f021591e4b8c9d89846b9ce9de57
Autor:
Annamaria G. NUCERA, Vittoria LOPEZ
Publikováno v:
Journal of Radiological Review. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5289ee719351d0c84ea69e9359e5b96d
https://doi.org/10.23736/s2723-9284.22.00187-1
https://doi.org/10.23736/s2723-9284.22.00187-1
Autor:
Nina Geiger, Dominik Thimm, Thanigaimalai Pillaiyar, Robin Gedschold, Laura Schäkel, Michael Gütschow, Christa E. Müller, Ghazl Al Hamwi, Maria Zyulina, Vittoria Lopez, Christin Vielmuth, Katharina Sylvester, Miriam Diett, Lan Phuong Vu, Vigneshwaran Namasivayam, Julian Breidenbach, Anke C. Schiedel, Jochen Bodem, Salahuddin Mirza, Carina Lemke
Publikováno v:
Angewandte Chemie. 133:10515-10521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff9821b9fd888dcc360c6ff44e464c3
https://doi.org/10.1002/ange.202016961
https://doi.org/10.1002/ange.202016961
Publikováno v:
Journal of Radiological Review. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe36b9870c4a5abc8dcab32ca53135c9
https://doi.org/10.23736/s2723-9284.21.00170-8
https://doi.org/10.23736/s2723-9284.21.00170-8
Autor:
Laura Schäkel, Salahuddin Mirza, Riekje Winzer, Vittoria Lopez, Riham Idris, Haneen Al-Hroub, Julie Pelletier, Jean Sévigny, Eva Tolosa, Christa E Müller
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e004660
BackgroundAn important mechanism, by which cancer cells achieve immune escape, is the release of extracellular adenosine into their microenvironment. Adenosine activates adenosine A2A and A2B receptors on immune cells constituting one of the stronges
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2048c73c4e6125db35a0fd9ff31ccd9c
https://doi.org/10.1136/jitc-2022-004660
https://doi.org/10.1136/jitc-2022-004660
Autor:
Salahuddin Mirza, Carina Lemke, Robin Gedschold, Dominik Thimm, Miriam Diett, Nina Geiger, Christa E. Müller, Julian Breidenbach, Michael Gütschow, Jochen Bodem, Christin Vielmuth, Anke C. Schiedel, Katharina Sylvester, Vittoria Lopez, Lan Phuong Vu, Vigneshwaran Namasivayam, Thanigaimalai Pillaiyar, Laura Schäkel, Ghazl Al Hamwi, Maria Zyulina
Publikováno v:
Angewandte Chemie (International Ed. in English)
The main protease of SARS‐CoV‐2 (Mpro), the causative agent of COVID‐19, constitutes a significant drug target. A new fluorogenic substrate was kinetically compared to an internally quenched fluorescent peptide and shown to be ideally suitable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad0987f44a1481deac8275f2d5abd33
http://europepmc.org/articles/PMC8014119
http://europepmc.org/articles/PMC8014119
Autor:
Susanne Alban, Christa E. Müller, Michael Schmidt, Julie Pelletier, Sang-Yong Lee, Jean Sévigny, Laura Schäkel, Gerd Bendas, H. J. Maximilian Schuh, Vittoria Lopez, Salahuddin Mirza, Christian Renn
Publikováno v:
Marine Drugs, Vol 19, Iss 51, p 51 (2021)
Marine Drugs
Volume 19
Issue 2
Marine Drugs
Volume 19
Issue 2
Extracellular ATP mediates proinflammatory and antiproliferative effects via activation of P2 nucleotide receptors. In contrast, its metabolite, the nucleoside adenosine, is strongly immunosuppressive and enhances tumor proliferation and metastasis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ad135be4ffc4d16236bc8817924b6af
https://doi.org/10.3390/md19020051
https://doi.org/10.3390/md19020051