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The Epistasis Project: A Multi-Cohort Study of the Effects of BDNF, DBH, and SORT1 Epistasis on Alzheimer's Disease Risk

Autor: Belbin, O, Morgan, K, Medway, C, Warden, D, Cortina-Borja, M, Van Duijn, CM, Adams, HHH, Frank-Garcia, A, Brookes, K, Sánchez-Juan, P, Alvarez, V, Heun, R, Kölsch, H, Coto, E, Kehoe, PG, Rodriguez-Rodriguez, E, Bullido, MJ, Ikram, MA, Smith, AD, Lehmann, DJ, Vitorica, J

Publikováno v: Belbin, O, Morgan, K, Medway, C, Warden, D, Cortina-Borja, M, van Duijn, C M, Adams, H H H, Brookes, K, Sanchez-Juan, P, Frank-Garcia, A, Alvarez, V, Heun, R, Kölsch, H, Coto, E, Kehoe, P, Rodriguez-Rodriguez, E, Bullido, M, Ikram, M A, Smith, A D & Lehmann, D 2019, ' The Epistasis Project : A Multi-Cohort Study of the Effects of BDNF, DBH, and SORT1 Epistasis on Alzheimer’s Disease Risk ', Journal of Alzheimer's Disease, vol. 68, no. 4, pp. 1535-1547 . https://doi.org/10.3233/JAD-181116
JOURNAL OF ALZHEIMERS DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Digital.CSIC. Repositorio Institucional del CSIC
Journal of Alzheimers Disease, 68(4), 1535-1547. IOS Press BV

Pre-synaptic secretion of brain-derived neurotrophic factor (BDNF) from noradrenergic neurons may protect the Alzheimer's disease (AD) brain from amyloid pathology. While the BDNF polymorphism (rs6265) is associated with faster cognitive decline and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65f01ce209bf184d53e9a78d90edb969
https://pure.eur.nl/en/publications/67c05f4a-3ff8-4e02-ac89-449919147428

Non-productive angiogenesis disassembles A ss plaque-associated blood vessels

Autor: Alvarez-Vergara M, Rosales-Nieves A, March-Diaz R, Rodriguez-Perinan G, Lara-Urena N, San Luis C, Sanchez-Garcia M, Martin-Bornez M, Gomez-Galvez P, Vicente-Munuera P, Fernandez-Gomez B, Marchena M, Bullones-Bolanos A, Davila J, Gonzalez-Martinez R, Trillo-Contreras J, Sanchez-Hidalgo A, del Toro R, Scholl F, Herrera E, Trepel M, Korbelin J, Escudero L, Villadiego J, Echevarria M, de Castro F, Gutierrez A, Rabano A, Vitorica J, Pascual A

Publikováno v: NATURE COMMUNICATIONS
r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante
instname

The human Alzheimer's disease (AD) brain accumulates angiogenic markers but paradoxically, the cerebral microvasculature is reduced around A ss plaques. Here we demonstrate that angiogenesis is started near A ss plaques in both AD mouse models and hu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::82e8c0df034ef689b954221e24dbe8bc
https://fundanet.isabial.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=8650

Brain tissue recovery in obstructive congenital hydrocephalus after intraventricular transplantation of mesenchymal stem cells

Autor: García-Bonilla, María, Ojeda-Pérez, B., Shumilov, Kirill, Vitorica, J., García-Martín, María Luisa, Muñoz, Carmen, Gutierrez-Perez, Antonia, Jimenez-Lara, Antonio Jesus, Páez-González, Patricia

Publikováno v: RIUMA. Repositorio Institucional de la Universidad de Málaga
instname

Introduction: Bone marrow-derived mesenchymal stem cells (BM-MSC) are a potential therapeutic tool due to their ability for migrating and producing neuroprotector factors when transplanted. The aim of this study was to evaluate the short-time effects

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=RECOLECTA___::c06915238ac985b1ebb83a59900c4358
https://hdl.handle.net/10630/16737

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