Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Vitor Won-Held Rabelo"'
Autor:
Kauê Francisco Corrêa de Souza e Souza, Vitor Won-Held Rabelo, Paula Alvarez Abreu, Cláudio César Cirne Santos, Nayane Abreu do Amaral e Silva, Daniela de Luna, Vitor Francisco Ferreira, Bernardo Ferreira Braz, Ricardo Erthal Santelli, Cassiano Felippe Gonçalves-de-Albuquerque, Izabel Christina Nunes de Palmer Paixão, Patricia Burth
Publikováno v:
ACS Omega, Vol 9, Iss 34, Pp 36835-36846 (2024)
Externí odkaz:
https://doaj.org/article/7f730c88e4fb4e02bb7919d986b84f41
Autor:
Bruna Costa Zorzanelli, Gabriel Ouverney, Fernanda P. Pauli, Anna Carolina Carvalho da Fonseca, Elan Cardozo Paes de Almeida, Danielle Gonçalves de Carvalho, Patricia Abrão Possik, Vitor Won-Held Rabelo, Paula Alvarez Abreu, Bruno Pontes, Vitor Francisco Ferreira, Luana da Silva Magalhães Forezi, Fernando de Carvalho da Silva, Bruno Kaufmann Robbs
Publikováno v:
Molecules, Vol 27, Iss 16, p 5148 (2022)
Oral squamous cell carcinoma (OSCC) is a global public health problem with high incidence and mortality. The chemotherapeutic agents used in the clinic, alone or in combination, usually lead to important side effects. Thus, the discovery and developm
Externí odkaz:
https://doaj.org/article/b9489feec4eb49ff85c08573fb21ef3c
Autor:
Claudio Cesar Cirne-Santos, Valéria Laneuville Teixeira, Max Willian Lisboa Gomes, Priscilla O. Esteves, Vitor Won-Held Rabelo, Caroline de Souza Barros, Izabel C N de
Publikováno v:
Acta virologica. 65:402-410
Zika virus (ZIKV) is an arthropod-borne flavivirus that reemerged in 2007 and, since then, has caused several outbreaks and spread to over 80 countries worldwide. Along with this, ZIKV infections have been associated with severe clinical outcomes, in
Autor:
Vitor Won-Held Rabelo, Fernando Dias da Silva, Beatriz Matuck, Vítor Sérgio Ferreira, Luiz Cláudio Rodrigues Pereira da Silva, Dora C. S. Costa, Adriane Francisco, Plínio Cunha Sathler, Paula Alvarez Abreu, Priscila de Souza Furtado, Alana de Oliveira
Publikováno v:
Journal of the Brazilian Chemical Society.
Acetylated compounds prepared from naphthoquinones have been reported as antitumoral prodrugs. Exploring the synthetic versatility of the naphthoquinone and triazolic nuclei, herein we report a simple and efficient synthetic route to prepare a series
Autor:
Nelilma C. Romeiro, Paula Alvarez Abreu, Izabel Christina Nunes de Palmer Paixão, Vitor Won-Held Rabelo
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 38:2116-2127
Herpes simplex virus type 1 (HSV-1) infections affect about two-thirds of the world population, and the standard treatment consists of acyclovir (ACV) and its analogs, which interact with thymidine kinase (TK) blocking viral replication. Lately, the
Autor:
Daiane de Jesus Viegas, Nelilma C. Romeiro, Erline Machado Neves Tucci, Paula Alvarez Abreu, Vitor Won-Held Rabelo
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 185:189-199
Candidiasis is the most common fungal infection in immunocompromised patients, and Candida albicans is the fourth leading agent of nosocomial infections. Mortality from this infection is significant; however, the therapeutic treatment is limited, whi
Autor:
Elan Cardozo Paes de Almeida, Anna Carolina Carvalho da Fonseca, Lucas N. de Queiroz, Ingrid C. Chipoline, Fernando de C. da Silva, Theo Luiz Ferraz de Souza, Bruno K. Robbs, Gabriella Ribeiro Machado da Costa, Bruno Pontes, Vitor F. Ferreira, Michele Pereira de Souza, Paula Alvarez Abreu, Vitor Won-Held Rabelo
Publikováno v:
Bioorganic chemistry. 101
The oral squamous cell carcinoma (OSCC) stands out as a public health problem due to its high incidence and low survival rate, despite advances in diagnosis and treatment. Moreover, the most commonly chemotherapeutic agents for OSCC, such as carbopla
Publikováno v:
Expert opinion on therapeutic targets. 24(1)
Introduction: Chikungunya virus (CHIKV) is the causative agent of Chikungunya fever, a reemerging infectious disease. This disease can cause severe manifestations that persist for months or...
Autor:
Alexander Sibajev, Vitor Won-Held Rabelo, Rebeca Pereira, Helena Carla Castro, Paula Alvarez Abreu
Publikováno v:
Journal of Biotechnology. 279:37-46
β-lactams are one of the most common antimicrobials used to treat bacterial infections. However, bacterial resistance has compromised their efficacy, mainly due to the β-lactamase enzyme production. To overcome this resistance, β-lactamase inhibit
Publikováno v:
Computers in Biology and Medicine. 136:104694
Mycobacterium tuberculosis was discovered in 1882 by Robert Koch but, since its discovery, the tuberculosis (TB) epidemic has endured, being one of the top 10 causes of death worldwide. Drug-resistant TB continues to be a public health threat and bio