Zobrazeno 1 - 10 of 24 pro vyhledávání: '"Vitor Silva Pereira"'
1
Akademický článek
ZL006, a small molecule inhibitor of PSD-95/nNOS interaction, does not induce antidepressant-like effects in two genetically predisposed rat models of depression and control animals.
Autor: Sandra Tillmann, Vitor Silva Pereira, Nico Liebenberg, Anne Karina Christensen, Gregers Wegener
Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0182698 (2017)
N-methyl-D-aspartate receptor (NMDA-R) antagonists and nitric oxide inhibitors have shown promising efficacy in depression but commonly induce adverse events. To circumvent these, a more indirect disruption of the nitric oxide synthase/postsynaptic d
Externí odkaz: https://doaj.org/article/8e939364e85848aaa92db44d56c09851
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2
Dissertation/ Thesis
Participação da via NMDA-NO do córtex pré-frontal medial ventral na modulação das consequências comportamentais do estresse de nado forçado: mecanismos intracelulares
Autor: Vitor Silva Pereira
Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
PEREIRA, V.S. Participação da via NMDA-NO do córtex pré-frontal medial ventral na modulação das consequências comportamentais do estresse de nado forçado: mecanismos intracelulares. 2015. 191p. Tese (Doutorado) Faculdade de Medicina de Ribeir
Externí odkaz: http://www.teses.usp.br/teses/disponiveis/17/17133/tde-07072015-084140/
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3
Dissertation/ Thesis
Participação do sistema glutamatérgico do córtex pré-frontal medial ventral na modulação das consequências comportamentais do estresse de nado forçado
Autor: Vitor Silva Pereira
Publikováno v: Biblioteca Digital de Teses e Dissertações da USPUniversidade de São PauloUSP.
Acredita-se que quantidades elevadas de glutamato estejam relacionadas à neurobiologia da depressão e trabalhos recentes indicam que a quantidade de glutamato cortical está aumentada em pacientes depressivos quando comparada a indivíduos sadios.
Externí odkaz: http://www.teses.usp.br/teses/disponiveis/17/17133/tde-11082011-132630/
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4
Prelimbic neuronal nitric oxide synthase inhibition exerts antidepressant-like effects independently of BDNF signalling cascades
Autor: Vitor Silva Pereira, Gregers Wegener, Angélica C D Romano Suavinha, Sâmia R.L. Joca
Publikováno v: Pereira, V S, Suavinha, A C D R, Wegener, G & Joca, S R L 2019, ' Prelimbic neuronal nitric oxide synthase inhibition exerts antidepressant-like effects independently of BDNF signalling cascades ', Acta Neuropsychiatrica, vol. 31, no. 3, pp. 143-150 . https://doi.org/10.1017/neu.2018.39
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
ObjectivesNMDA antagonists and nitric oxide synthase (NOS) inhibitors induce antidepressant-like effects and may represent treatment options for depression. The behavioural effects of NMDA antagonists seem to depend on Tyrosine kinase B receptor (Trk
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c593ff0c54d168052262db17f9677ee9
https://doi.org/10.1017/neu.2018.39
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5
Esketamine and rapastinel, but not imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression
Autor: Gregers Wegener, Sâmia R.L. Joca, Vitor Silva Pereira, Brian H. Harvey, Betina Elfving
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Pereira, V S, Joca, S R L, Harvey, B H, Elfving, B & Wegener, G 2019, ' Esketamine and Rapastinel, but not Imipramine, have antidepressant-like effect in a treatment-resistant animal model of depression ', Acta Neuropsychiatrica, vol. 31, no. 5, pp. 258-265 . https://doi.org/10.1017/neu.2019.25
Objectives:Treatment-resistance to antidepressants is a major problem in the pharmacotherapy of major depressive disorder (MDD). Unfortunately, only a few animal models are suitable for studying treatment-resistant depression, among them repeated tre
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a6ac7764e4cf40a55a6a58d2d592ed
https://pubmed.ncbi.nlm.nih.gov/31230597
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6
Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex
Autor: Francisco Silveira Guimarães, Gregers Wegener, Manoela V. Fogaça, Amanda J. Sales, Sâmia R.L. Joca, Ariandra G. Sartim, Vitor Silva Pereira
Publikováno v: Sales, A J, Fogaça, M V, Sartim, A G, Pereira, V S, Wegener, G, Guimarães, F S & Joca, S R L 2019, ' Cannabidiol Induces Rapid and Sustained Antidepressant-Like Effects Through Increased BDNF Signaling and Synaptogenesis in the Prefrontal Cortex ', Molecular Neurobiology, vol. 56, no. 2, pp. 1070–1081 . https://doi.org/10.1007/s12035-018-1143-4
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Currently available antidepressants have a substantial time lag to induce therapeutic response and a relatively low efficacy. The development of drugs that addresses these limitations is critical to improving public health. Cannabidiol (CBD), a non-p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb2d7ad132789267ed5b92fdcf06dfcd
https://pure.au.dk/portal/da/publications/cannabidiol-induces-rapid-and-sustained-antidepressantlike-effects-through-increased-bdnf-signaling-and-synaptogenesis-in-the-prefrontal-cortex(9b621519-a8a9-4a95-a9c1-9b388710507f).html
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9
A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania
Autor: Erik Jensen, Christina W. Fischer, Nico Liebenberg, Erik Roj Larsen, Vitor Silva Pereira, Gregers Wegener, Birgitte S. Kousholt
Publikováno v: Liebenberg, N, Jensen, E, Larsen, E R, Kousholt, B S, Pereira, V S, Fischer, C W & Wegener, G 2018, ' A Preclinical Study of Casein Glycomacropeptide as a Dietary Intervention for Acute Mania ', International Journal of Neuropsychopharmacology, vol. 21, no. 5, pp. 473-484 . https://doi.org/10.1093/ijnp/pyy012
International Journal of Neuropsychopharmacology
Background: Casein glycomacropeptide is a peptide that lacks phenylalanine, tyrosine, and tryptophan. This profile may enable it to deplete phenylalanine, tyrosine, and tryptophan, and subsequently the synthesis of dopamine and serotonin in the brain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79185364bc7fef36cacd99783cafaa39
https://findresearcher.sdu.dk:8443/ws/files/140658810/A_Preclinical_Study_of_Casein_Glycomacropeptide_as_a_Dietary_Intervention_for_Acute_Mania.pdf
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10
Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test
Autor: Angélica Romano, Vitor Silva Pereira, Gregers Wegener, Sâmia R.L. Joca
Publikováno v: Pereira, V S, Romano, A, Wegener, G & Joca, S 2015, ' Antidepressant-like effects induced by NMDA receptor blockade and NO synthesis inhibition in the ventral medial prefrontal cortex of rats exposed to the forced swim test ', Psychopharmacology . https://doi.org/10.1007/s00213-014-3853-2
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
RATIONALE: Systemic treatment with NMDA receptor (NMDAR) antagonists, inhibitors of neuronal nitric oxide synthase (nNOS) or of soluble guanylyl cyclase (sGC), induce antidepressant-like effects in rats. Increased levels of glutamate and nitric oxide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60039c473766b2db597a788028e1784c
https://doi.org/10.1007/s00213-014-3853-2
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