Zobrazeno 1 - 10 of 21 pro vyhledávání: '"Vitor R. C. Aguiar"'
1
Akademický článek
High-throughput identification of functional regulatory SNPs in systemic lupus erythematosus
Autor: Qiang Wang, Taehyeung Kim, Marta Martínez-Bonet, Vitor R. C. Aguiar, Sangwan Sim, Jing Cui, Jeffrey A. Sparks, Xiaoting Chen, Marc Todd, Brian Wauford, Miranda C. Marion, Carl D. Langefeld, Matthew T. Weirauch, Maria Gutierrez-Arcelus, Peter A. Nigrovic
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Genome-wide association studies implicate multiple loci in risk for systemic lupus erythematosus (SLE), but few contain exonic variants, rendering systematic identification of non-coding variants essential to decoding SLE genetics. We utiliz
Externí odkaz: https://doaj.org/article/1e3df32c4843408cb3495d4e0d4bcf9e
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2
Akademický článek
Non-coding autoimmune risk variant defines role for ICOS in T peripheral helper cell development
Autor: Taehyeung Kim, Marta Martínez-Bonet, Qiang Wang, Nicolaj Hackert, Jeffrey A. Sparks, Yuriy Baglaenko, Byunghee Koh, Roxane Darbousset, Raquel Laza-Briviesca, Xiaoting Chen, Vitor R. C. Aguiar, Darren J. Chiu, Harm-Jan Westra, Maria Gutierrez-Arcelus, Matthew T. Weirauch, Soumya Raychaudhuri, Deepak A. Rao, Peter A. Nigrovic
Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Fine-mapping and functional studies implicate rs117701653, a non-coding single nucleotide polymorphism in the CD28/CTLA4/ICOS locus, as a risk variant for rheumatoid arthritis and type 1 diabetes. Here, using DNA pulldown, mass spectrometry,
Externí odkaz: https://doaj.org/article/89591f74d78449f789de95d34d7df2b8
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3
Akademický článek
An immunogenetic view of COVID-19
Autor: Vitor R. C. Aguiar, Danillo G. Augusto, Erick C. Castelli, Jill A. Hollenbach, Diogo Meyer, Kelly Nunes, Maria Luiza Petzl-Erler
Publikováno v: Genetics and Molecular Biology, Vol 44, Iss 1 suppl 1 (2021)
Abstract Meeting the challenges brought by the COVID-19 pandemic requires an interdisciplinary approach. In this context, integrating knowledge of immune function with an understanding of how genetic variation influences the nature of immunity is a k
Externí odkaz: https://doaj.org/article/dfb43c8b79404c4d93935ceb43a680b4
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4
Akademický článek
How Ancestry Influences the Chances of Finding Unrelated Donors: An Investigation in Admixed Brazilians
Autor: Kelly Nunes, Vitor R. C. Aguiar, Márcio Silva, Alexandre C. Sena, Danielli C. M. de Oliveira, Carla L. Dinardo, Fernanda S. G. Kehdy, Eduardo Tarazona-Santos, Vanderson G. Rocha, Anna Barbara F. Carneiro-Proietti, Paula Loureiro, Miriam V. Flor-Park, Claudia Maximo, Shannon Kelly, Brian Custer, Bruce S. Weir, Ester C. Sabino, Luís Cristóvão Porto, Diogo Meyer
Publikováno v: Frontiers in Immunology, Vol 11 (2020)
A match of HLA loci between patients and donors is critical for successful hematopoietic stem cell transplantation. However, the extreme polymorphism of HLA loci – an outcome of millions of years of natural selection – reduces the chances that tw
Externí odkaz: https://doaj.org/article/7135c23b854d4ea48891ccb520ebe641
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6
An immunogenetic view of COVID-19
Autor: Jill A. Hollenbach, Danillo G. Augusto, Kelly Nunes, Maria Luiza Petzl-Erler, Vitor R. C. Aguiar, Erick C. Castelli, Diogo Meyer
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Genetics and Molecular Biology, Volume: 44, Issue: 1 Supplement 1, Article number: e20210036, Published: 25 AUG 2021
Genetics and Molecular Biology
Genetics and Molecular Biology v.44 n.1 suppl.1 2021
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and molecular biology, vol 44, iss 1 Suppl 1
Genetics and Molecular Biology, Vol 44, Iss 1 suppl 1 (2021)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Made available in DSpace on 2022-04-29T08:32:46Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 National Institutes of Health Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) Meeting the challenges brought by the CO
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c65605c95d68a8f48487b384fa1389b3
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7
Assessing false paternity risk in simulated motherless cases from more than 20 000 real exclusion trios
Autor: Iúri Drumond Louro, Alessandro C. S. Ferreira, Eldamária de Vargas Wolfgramm dos Santos, Vitor R. C. Aguiar, Laélia M. Pinto, Amanda Mafia de Castro
Publikováno v: TransfusionREFERENCES. 61(3)
BACKGROUND When the mother's DNA profile is not available for paternity testing, there is a smaller probability that a locus will exclude an alleged father. This study aims to evaluate the risk of potential false paternity inclusions in motherless ca
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2ef6574e4c3ff294c5f4866cc45b772
https://pubmed.ncbi.nlm.nih.gov/33084042
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8
HLApers: HLA Typing and Quantification of Expression with Personalized Index
Autor: Vitor R C, Aguiar, Cibele, Masotti, Anamaria A, Camargo, Diogo, Meyer
Publikováno v: Methods in molecular biology (Clifton, N.J.). 2120
The plethora of RNA-seq data which have been generated in the recent years constitutes an attractive resource to investigate HLA variation and its relationship with normal and disease phenotypes, such as cancer. However, next generation sequencing (N
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6272e6141fd5bd10006ed9f22e082f1b
https://pubmed.ncbi.nlm.nih.gov/32124314
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9
HLApers: HLA Typing and Quantification of Expression with Personalized Index
Autor: Cibele Masotti, Anamaria A. Camargo, Diogo Meyer, Vitor R. C. Aguiar
Publikováno v: Bioinformatics for Cancer Immunotherapy ISBN: 9781071603260
The plethora of RNA-seq data which have been generated in the recent years constitutes an attractive resource to investigate HLA variation and its relationship with normal and disease phenotypes, such as cancer. However, next generation sequencing (N
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ec3e1d3bf16ba5774dfdaceaa69163bc
https://doi.org/10.1007/978-1-0716-0327-7_7
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10
A genomic perspective on HLA evolution
Autor: Bárbara Domingues Bitarello, Débora Y. C. Brandt, Diogo Meyer, Kelly Nunes, Vitor R. C. Aguiar
Publikováno v: Immunogenetics
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Several decades of research have convincingly shown that classical human leukocyte antigen (HLA) loci bear signatures of natural selection. Despite this conclusion, many questions remain regarding the type of selective regime acting on these loci, th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53593b4e42a213947e01f358c4178f5
https://doi.org/10.1007/s00251-017-1017-3
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