Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Vito Valiante"'
Publikováno v:
mBio, Vol 15, Iss 6 (2024)
ABSTRACT Amoebae are environmental predators feeding on bacteria, fungi, and other eukaryotic microbes. Predatory interactions alter microbial communities and impose selective pressure toward phagocytic resistance or escape which may, in turn, foster
Externí odkaz:
https://doaj.org/article/fb0460f5674644b1bda92205b53df368
Autor:
Katarina Jojić, Fabio Gherlone, Zoltán Cseresnyés, Alexander U. Bissell, Sandra Hoefgen, Stefan Hoffmann, Ying Huang, Slavica Janevska, Marc Thilo Figge, Vito Valiante
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Sphingofungins are sphinganine analog mycotoxins acting as inhibitors of serine palmitoyl transferases, enzymes responsible for the first step in the sphingolipid biosynthesis. Eukaryotic cells are highly organized with various structures an
Externí odkaz:
https://doaj.org/article/1590b18aa1de4795b6dcabe17f244522
Autor:
Florian Riedel, Maria Puertas Bartolomé, Lara Luana Teruel Enrico, Claudia Fink-Straube, Cao Nguyen Duong, Fabio Gherlone, Ying Huang, Vito Valiante, Aránzazu Del Campo, Shrikrishnan Sankaran
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Microbial biofactories allow the upscaled production of high-value compounds in biotechnological processes. This is particularly advantageous for compounds like flavonoids that promote better health through their antioxidant, anti-bacterial, anti-can
Externí odkaz:
https://doaj.org/article/2c366a00314e4698864595e98e85c8de
Publikováno v:
Microbial Cell Factories, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background The availability of new biological platform organisms to get access to innovative products and processes is fundamental for the progress in biotechnology and bioeconomy. The amoeba Dictyostelium discoideum represents a novel host
Externí odkaz:
https://doaj.org/article/961d335ecf9d4f7a8669ac1f2ea71b74
Autor:
Sandra Hoefgen, Alexander U. Bissell, Ying Huang, Fabio Gherlone, Luka Raguž, Christine Beemelmanns, Vito Valiante
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 5 (2022)
ABSTRACT Serine palmitoyltransferase catalyzes the first step of the sphingolipid biosynthesis. Recently, sphingolipid homeostasis has been connected to several human diseases, making serine palmitoyltransferases an interesting therapeutic target. Kn
Externí odkaz:
https://doaj.org/article/a3b04fd7641243648624375f92b171f7
Autor:
Slavica Janevska, Iuliia Ferling, Katarina Jojić, Julia Rautschek, Sandra Hoefgen, Robert H. Proctor, Falk Hillmann, Vito Valiante
Publikováno v:
mBio, Vol 11, Iss 3 (2020)
ABSTRACT Fumonisin (FB) mycotoxins produced by species of the genus Fusarium detrimentally affect human and animal health upon consumption, due to the inhibition of ceramide synthase. In the present work, we set out to identify mechanisms of self-pro
Externí odkaz:
https://doaj.org/article/b07819250cac40d8bbc977bfb407b14c
Autor:
Maria Cristina Stroe, Tina Netzker, Kirstin Scherlach, Thomas Krüger, Christian Hertweck, Vito Valiante, Axel A Brakhage
Publikováno v:
eLife, Vol 9 (2020)
Microorganisms produce numerous secondary metabolites (SMs) with various biological activities. Many of their encoding gene clusters are silent under standard laboratory conditions because for their activation they need the ecological context, such a
Externí odkaz:
https://doaj.org/article/308f7260697949bb9d5fdad18446aea5
Autor:
Adriana Oliveira Manfiolli, Filipe Silva Siqueira, Thaila Fernanda dos Reis, Patrick Van Dijck, Sanne Schrevens, Sandra Hoefgen, Martin Föge, Maria Straßburger, Leandro José de Assis, Thorsten Heinekamp, Marina Campos Rocha, Slavica Janevska, Axel A. Brakhage, Iran Malavazi, Gustavo H. Goldman, Vito Valiante
Publikováno v:
mBio, Vol 10, Iss 2 (2019)
ABSTRACT The pathogenic fungus Aspergillus fumigatus is able to adapt to extremely variable environmental conditions. The A. fumigatus genome contains four genes coding for mitogen-activated protein kinases (MAPKs), which are important regulatory kno
Externí odkaz:
https://doaj.org/article/2a88a6e1f3f546b38da33b11a7706562
Autor:
Juliane Fischer, Sebastian Y Müller, Tina Netzker, Nils Jäger, Agnieszka Gacek-Matthews, Kirstin Scherlach, Maria C Stroe, María García-Altares, Francesco Pezzini, Hanno Schoeler, Michael Reichelt, Jonathan Gershenzon, Mario KC Krespach, Ekaterina Shelest, Volker Schroeckh, Vito Valiante, Thorsten Heinzel, Christian Hertweck, Joseph Strauss, Axel A Brakhage
Publikováno v:
eLife, Vol 7 (2018)
The eukaryotic epigenetic machinery can be modified by bacteria to reprogram the response of eukaryotes during their interaction with microorganisms. We discovered that the bacterium Streptomyces rapamycinicus triggered increased chromatin acetylatio
Externí odkaz:
https://doaj.org/article/cafdcfa42f084b8b805c8be272eef709
Autor:
Volker U Schwartze, Sascha Winter, Ekaterina Shelest, Marina Marcet-Houben, Fabian Horn, Stefanie Wehner, Jörg Linde, Vito Valiante, Michael Sammeth, Konstantin Riege, Minou Nowrousian, Kerstin Kaerger, Ilse D Jacobsen, Manja Marz, Axel A Brakhage, Toni Gabaldón, Sebastian Böcker, Kerstin Voigt
Publikováno v:
PLoS Genetics, Vol 12, Iss 12, p e1006491 (2016)
[This corrects the article DOI: 10.1371/journal.pgen.1004496.].
Externí odkaz:
https://doaj.org/article/b293248bce1f4048befcd47cfe06e1dc