Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Vito Spataro"'
Autor:
Vito Spataro, Antoine Buetti-Dinh
Publikováno v:
Translational Medicine Communications, Vol 9, Iss 1, Pp 1-13 (2024)
Abstract Background The 26S proteasome is a large intracellular multiprotein complex, that plays a homeostatic role by degrading proteins that have been tagged by ubiquitin. It is composed of 64 subunits assembled according to a well-defined structur
Externí odkaz:
https://doaj.org/article/cba6ed4bca124b0a802c521b9c9f2d87
Autor:
Vito Spataro, Antoine Buetti-Dinh
Publikováno v:
British journal of cancer. 127(5)
POH1/Rpn11/PSMD14 is a highly conserved protein in eukaryotes from unicellular organisms to human and has a crucial role in cellular homoeostasis. It is a subunit of the regulatory particle of the proteasome, where it acts as an intrinsic deubiquitin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5e23da87e4ed9ec70f3778c4b59b15d
https://pubmed.ncbi.nlm.nih.gov/35501388
https://pubmed.ncbi.nlm.nih.gov/35501388
Autor:
Nasian Mosku, Philip Heesen, Gabriela Studer, Beata Bode, Vito Spataro, Natalie D. Klass, Lars Kern, Mario F. Scaglioni, Bruno Fuchs
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1632
The ratio of malignancy in suspicious soft tissue and bone neoplasms (RMST) has not been often addressed in the literature. However, this value is important to understand whether biopsies are performed too often, or not often enough, and may therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7d14bd1b71812f60fd17eab9da6724
https://doi.org/10.3390/cancers14071632
https://doi.org/10.3390/cancers14071632
Autor:
Vito Spataro
Publikováno v:
Journal of Cancer Policy. 29:100289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fc1769717e1b7868a651b1f1b6e459d
https://doi.org/10.1016/j.jcpo.2021.100289
https://doi.org/10.1016/j.jcpo.2021.100289
Autor:
Vito Spataro, Gee-Chen Chang, Mojca Unk, Wei-Yu Liao, Philippe Carrière, Alessandra Curioni-Fontecedro, Hovav Nechushtan, Jin-Yuan Shih, James Chih-Hsin Yang, Robert M. Lorence, Agnieszka Cseh, Solange Peters, Oliver Gautschi
Publikováno v:
Journal of thoracic oncology, vol. 13, no. 12, pp. 1897-1905
Introduction Approximately 1% to 4% of NSCLC tumors harbor erb-b2 receptor tyrosine kinase 2 (ERBB2) mutation; there is no approved targeted treatment for this subgroup. Methods Patients with stage IV NSCLC that progressed after clinical benefit on e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3a46737805b345849c87401cd2e9620
https://serval.unil.ch/notice/serval:BIB_29FF3A29D783
https://serval.unil.ch/notice/serval:BIB_29FF3A29D783
Publikováno v:
Journal of painpalliative care pharmacotherapy. 31(1)
Refractory pain is a common manifestation in an oncologic palliative care setting and represents a major challenge for health care professionals involved in care provision. The underlying neoplasm and its dissemination are the foremost pathophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::164b8577fec9e08015ac2ea65d3662ea
https://pubmed.ncbi.nlm.nih.gov/28287358
https://pubmed.ncbi.nlm.nih.gov/28287358
Autor:
Alfred Zippelius, Christian Monnerat, Christian Spirig, Michael Mark, Cathrin Balmelli, Andreas Wicki, Stefanie Pederiva, Vito Spataro
Publikováno v:
memo - Magazine of European Medical Oncology. 7:181-186
Vemurafenib is a targeted therapy against metastatic melanoma. It specifically inhibits the V600 mutated BRAF kinase in the mitogen-activated protein kinase pathway. Only limited data are available on long-term tolerability and efficacy of this drug.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::651367bef94e57710ee1c6457e06b255
https://doi.org/10.1007/s12254-014-0156-6
https://doi.org/10.1007/s12254-014-0156-6
Autor:
Alison Palmer, Tiziano Moccetti, Genoni M, Aldo P. Maggioni, Rory Collins, Vito Spataro, Sarah Parish, R Malacrida
Publikováno v:
New England Journal of Medicine. 338:8-14
Background In previous studies, unadjusted comparisons of mortality and major morbidity after acute myocardial infarction have generally indicated that women have a poorer outcome than men. Much larger studies are needed, with more complete adjustmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e910cc4df5d07badf71304be0e06cabc
https://doi.org/10.1056/nejm199801013380102
https://doi.org/10.1056/nejm199801013380102
Autor:
Vito Spataro
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 29(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e76793b43fa30ce8e7e3bc2d52772aa
https://pubmed.ncbi.nlm.nih.gov/20956624
https://pubmed.ncbi.nlm.nih.gov/20956624
Autor:
Sandro Pampallona, Marc Schapira, Vito Spataro, Tibor Kovacsovics, Franco Cavalli, Silvy Bach
Publikováno v:
Leukemialymphoma. 39(5-6)
We retrospectively assessed seventy-four consecutive patients with AML over 65 years of age (median 71; range 65-88) treated with an individualized approach in two specialized cancer centers. Patients were managed according to their performance statu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ab198b7f4f15f0adc9d549293cfc2e
https://pubmed.ncbi.nlm.nih.gov/11342335
https://pubmed.ncbi.nlm.nih.gov/11342335