Characterization of a Novel Mitochondrial Ascorbate Transporter From Rat Liver and Potato Mitochondria

Autor: Vito Scalera, Nicola Giangregorio, Silvana De Leonardis, Lara Console, Emanuele Salvatore Carulli, Annamaria Tonazzi

Publikováno v: Frontiers in Molecular Biosciences, Vol 5 (2018)

The Mitochondrial Ascorbic Acid Transporter (MAT) from both rat liver and potato mitochondria has been reconstituted in proteoliposomes. The protein has a molecular mass in the range of 28–35 kDa and catalyzes saturable, temperature and pH dependen

Externí odkaz: https://doaj.org/article/acb317069d9c495d91b40a078608ab8c

Tryptophan 224 of the rat mitochondrial carnitine/acylcarnitine carrier is crucial for the antiport mechanism

Autor: Lara Console, Nicola Giangregorio, Mariella Pistillo, Annamaria Tonazzi, Cesare Indiveri, Vito Scalera

Publikováno v: Biochimica et biophysica acta. Bioenergetics 1860 (2019): 708–716. doi:10.1016/j.bbabio.2019.07.006
info:cnr-pdr/source/autori:Nicola Giangregorio, Annamaria Tonazzi, Lara Console, Mariella Pistillo, Vito Scalera, Cesare Indiveri/titolo:Tryptophan 224 of the rat mitochondrial carnitine%2Facylcarnitine carrier is crucial for the antiport mechanism/doi:10.1016%2Fj.bbabio.2019.07.006/rivista:Biochimica et biophysica acta. Bioenergetics/anno:2019/pagina_da:708/pagina_a:716/intervallo_pagine:708–716/volume:1860

The mitochondrial carnitine/acylcarnitine carrier (CACT) catalyzes an antiport of carnitine and acylcarnitines and also a uniport reaction with a rate of about one tenth with respect to the antiport rate. The antiport process results from the couplin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d33cd77e96779a1f7e96c96f96eae552
https://doi.org/10.1016/j.bbabio.2019.07.006

F281, synthetic agonist of the sigma-2 receptor, induces Ca2+ efflux from the endoplasmic reticulum and mitochondria in SK-N-SH cells

Autor: Giuseppe Cassano, Marialessandra Contino, Giuseppe Gasparre, Mauro Niso, Nicola Antonio Colabufo, Vito Scalera

Publikováno v: Cell Calcium. 45:340-345

We demonstrate that F281, a synthetic agonist of the sigma-2 receptor (s2R), induces a non transient increase in intracellular [Ca(2+)] ([Ca(2+)](i)) and cell death in SK-N-SH cells. Sigma receptors are classified into two subtypes, with different mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::289fded8530407752b718325ead720fe
https://doi.org/10.1016/j.ceca.2008.12.005

myo-Inositol transport in rat intestinal brush border membrane vesicles, and its inhibition by d-glucose

Autor: D. Natuzzi, Vito Scalera, G. Prezioso

Publikováno v: Biochimica et Biophysica Acta (BBA) - Biomembranes. 1062:187-192

The uptake of myo -inositol into rat intestinal brush border membrane vesicles (BBMV) has been investigated. It is demonstrated that myo -inositol is transported into the vesicles by a secondary active process, specifically using the sodium gradient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af7f84b2d5e38e1497fe999e7d288cd
https://doi.org/10.1016/0005-2736(91)90391-k

Kinetic evidence for the uniport mechanism hypothesis in the mitochondrial tricarboxylate transport system

Autor: Vito Scalera, A. De Palma, G. Prezioso

Publikováno v: Journal of bioenergetics and biomembranes. 37(5)

The kinetics of the transport of citrate by the tricarboxylate transport system located in the inner mitochondrial membrane was studied in proteoliposomes containing the purified carrier protein, in order to verify the previously hypothesized mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6735dde681ecc227f849f48bb977fabb
https://pubmed.ncbi.nlm.nih.gov/16341772