Lipidomics reveals the reshaping of the mitochondrial phospholipid profile in cells lacking OPA1 and mitofusins

Autor: Andrea Castellaneta, Ilario Losito, Vito Porcelli, Serena Barile, Alessandra Maresca, Valentina Del Dotto, Valentina Losacco, Ludovica Sofia Guadalupi, Cosima Damiana Calvano, David C. Chan, Valerio Carelli, Luigi Palmieri, Tommaso R.I. Cataldi

Publikováno v: Journal of Lipid Research, Vol 65, Iss 6, Pp 100563- (2024)

Depletion or mutations of key proteins for mitochondrial fusion, like optic atrophy 1 (OPA1) and mitofusins 1 and 2 (Mfn 1 and 2), are known to significantly impact the mitochondrial ultrastructure, suggesting alterations of their membranes’ lipid

Externí odkaz: https://doaj.org/article/6589c03608d146cbb7ee3463e3fa33a0

Methyl carbamates of phosphatidylethanolamines and phosphatidylserines reveal bacterial contamination in mitochondrial lipid extracts of mouse embryonic fibroblasts

Autor: Andrea Castellaneta, Vito Porcelli, Ilario Losito, Serena Barile, Alessandra Maresca, Valentina Del Dotto, Ludovica Sofia Guadalupi, Cosima Damiana Calvano, Valerio Carelli, Luigi Palmieri, Tommaso R. I. Cataldi

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)

Abstract The occurrence of methyl carbamates of phosphatidylethanolamines and phosphatidylserines in the lipid extract of mitochondria obtained from mouse embryonic fibroblasts was ascertained by hydrophilic interaction liquid chromatography with ele

Externí odkaz: https://doaj.org/article/90836e2c7f57433ab8dac88e080a1b39

An Overview of Mitochondrial Protein Defects in Neuromuscular Diseases

Autor: Federica Marra, Paola Lunetti, Rosita Curcio, Francesco Massimo Lasorsa, Loredana Capobianco, Vito Porcelli, Vincenza Dolce, Giuseppe Fiermonte, Pasquale Scarcia

Publikováno v: Biomolecules, Vol 11, Iss 11, p 1633 (2021)

Neuromuscular diseases (NMDs) are dysfunctions that involve skeletal muscle and cause incorrect communication between the nerves and muscles. The specific causes of NMDs are not well known, but most of them are caused by genetic mutations. NMDs are g

Externí odkaz: https://doaj.org/article/32d8e5b4944a4c479666fbc332831895

CUGC for hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome

Autor: Giuseppe Fiermonte, Carlo Dionisi-Vici, Johannes Häberle, Sara Boenzi, Vito Porcelli, Emanuele Agolini, Bianca Maria Goffredo, Lorena Travaglini, Diego Martinelli

Publikováno v: Eur J Hum Genet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de78f25abf5f3e2c3c5eeb4ee9611abd
https://doi.org/10.1038/s41431-020-0616-x

Molecular identification and functional characterization of a novel glutamate transporter in yeast and plant mitochondria

Autor: Ruggiero, Gorgoglione, Vito, Porcelli, Angelo, Vozza, Roberto, Arrigoni, Flavia, Fontanesi, C. M.T., Marobbio, Ferdinando, Palmieri, Luigi, Palmieri.

Publikováno v: SECOND INTERNATIONAL GIBB MEETING GRUPPO ITALIANO DI BIOMEMBRANE E BIOENERGETICA, pp. 41–41, VIESTE (FG), Italy, 13-15/06/2019
info:cnr-pdr/source/autori:Ruggiero, Gorgoglione; Vito, Porcelli; Angelo, Vozza; Roberto, Arrigoni ; Flavia, Fontanesi; C. M.T., Marobbio; Ferdinando, Palmieri; Luigi, Palmieri./congresso_nome:SECOND INTERNATIONAL GIBB MEETING GRUPPO ITALIANO DI BIOMEMBRANE E BIOENERGETICA/congresso_luogo:VIESTE (FG), Italy/congresso_data:13-15%2F06%2F2019/anno:2019/pagina_da:41/pagina_a:41/intervallo_pagine:41–41

The importance of glutamate is well established in human as well as in plants and fungi where mitochondria play a key role in its metabolism[1,2]. Glutamate is transported inside and/or out from mitochondria by proteins localized in the inner mitocho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=cnr_________::9baf21d7d8fe6c9a0495b2038caddf6f
http://www.cnr.it/prodotto/i/435819