Effective decellularisation of human saphenous veins for biocompatible arterial tissue engineering applications: Bench optimisation and feasibility in vivo testing

Autor: Nadiah S Sulaiman, Andrew R Bond, Vito D Bruno, John Joseph, Jason L Johnson, M-Saadeh Suleiman, Sarah J George, Raimondo Ascione

Publikováno v: Journal of Tissue Engineering, Vol 12 (2021)

Human saphenous vein (hSV) and synthetic grafts are commonly used conduits in vascular grafting, despite high failure rates. Decellularising hSVs (D-hSVs) to produce vascular scaffolds might be an effective alternative. We assessed the effectiveness

Externí odkaz: https://doaj.org/article/62046e31c2f54310850ddd8ac08b28b9

Intramyocardial immunomodulation with human CD16+ monocytes to treat myocardial infarction in pig: a blind randomized preclinical trial

Autor: Raimondo Ascione, Vito D. Bruno, Tom Johnson, Eva Sammut, Andrew Bond, Daniel Lopez-Baz, Julia Deutsch, Mick Bailey, Amedeo Chiribiri, Ashish Patel, Andrew Baker, Bijan Modarai

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 11 (2024)

BackgroundHuman CD16+ monocytes (hCD16+ Ms) have proangiogenic properties. We assessed the feasibility, safety and efficacy of hCD16+ Ms in a porcine model of myocardial infarction (MI).Methods and resultsA total of 27 female Large White pigs underwe

Externí odkaz: https://doaj.org/article/1877606948434bdabbbc391240598256

Validation of the German Registry for Acute Aortic Dissection Type A Score in predicting 30-day mortality after type A aortic dissection surgery

Autor: Marco Gemelli, Ettorino Di Tommaso, Roberto Natali, Lauren Kari Dixon, Eltayeb Mohamed Ahmed, Cha Rajakaruna, Vito D Bruno

Publikováno v: European Journal of Cardio-Thoracic Surgery. 63

OBJECTIVES No reliable scores are available to predict mortality following surgery for type A acute aortic dissection (TAAAD). Recently, the German Registry of Acute Aortic Dissection Type A (GERAADA) score has been developed. We aim to compare how t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49667abb50eff932d0cf2f4cb6ed7ef7
https://doi.org/10.1093/ejcts/ezad141

MRI-based strain measurements reflect morphological changes following myocardial infarction: A study on the UK Biobank cohort

Autor: Doyin S. Mansell, Eva Sammut, Vito D. Bruno, Raimondo Ascione, Jonathan C. L. Rodrigues, Harinderjit S. Gill, Katharine H. Fraser, Andrew N. Cookson

Publikováno v: Odunmbaku-Mansell, D, Sammut, E, Bruno, V D, Ascione, R, Rodrigues, J C L, Gill, H S, Fraser, K & Cookson, A 2023, ' MRI-based strain measurements reflect morphological changes following myocardial infarction : A study on the UK Biobank cohort ', Journal Of Anatomy, vol. 242, no. 1, pp. 102-111 . https://doi.org/10.1111/joa.13787

In a porcine experimental model of myocardial infarction, a localised, layer-specific, circumferential left ventricular strain metric has been shown to indicate chronic changes in ventricular function post-infarction more strongly than ejection fract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::419941de4e9c06777c5ae40c4ab865fa
https://pubmed.ncbi.nlm.nih.gov/36484568

[Untitled]

Autor: Filippo Rapetto, Vito D. Bruno, Gustavo Guida, Roberto Marsico, Pierpaolo Chivasso, Carlo Zebele

Publikováno v: Drug Target Insights, Vol 10, Iss Suppl. 1 (2016)

Abstract non disponibile

Externí odkaz: https://doaj.org/article/62a8fad072374c61b8a2a85bdf641ab9