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Autor:
Toshihiro Matsui, Maria Pia Pistillo, Kusuki Nishioka, Carlo Gaudiano, Giovanni Battista Ferrara, Tomohiro Kato, Pier Luigi Tazzari, Vito Cilla, Paolo Capanni, Roberto Conte
Publikováno v:
Transfusion. 41:462-469
BACKGROUND: The presence of antibodies to CTLA-4, a negative regulator of T-cell activation, was investigated in multiply transfused patients with malignant and non- malignant hematologic diseases. A previous study showed that, in multiply transfused