Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Vitezslav Kriz"'
Autor:
Jiří Švec, Monika Šťastná, Lucie Janečková, Dušan Hrčkulák, Martina Vojtěchová, Jakub Onhajzer, Vítězslav Kříž, Kateřina Galušková, Eva Šloncová, Jan Kubovčiak, Lucie Pfeiferová, Jan Hrudka, Radoslav Matěj, Petr Waldauf, Lukáš Havlůj, Michal Kolář, Vladimír Kořínek
Publikováno v:
Cancers, Vol 14, Iss 17, p 4137 (2022)
Trophoblastic cell surface antigen 2 (TROP2) is a membrane glycoprotein overexpressed in many solid tumors with a poor prognosis, including intestinal neoplasms. In our study, we show that TROP2 is expressed in preneoplastic lesions, and its expressi
Externí odkaz:
https://doaj.org/article/d4924fcb3e974ca6993329e0a8c60641
Publikováno v:
Genes, Vol 10, Iss 10, p 788 (2019)
Colorectal cancer (CRC) is a heterogeneous disease that includes both hereditary and sporadic types of tumors. Tumor initiation and growth is driven by mutational or epigenetic changes that alter the function or expression of multiple genes. The gene
Externí odkaz:
https://doaj.org/article/240a2c88e0dc49679610dedb5fa18b4d
Autor:
Dusan Hrckulak, Lucie Janeckova, Lucie Lanikova, Vitezslav Kriz, Monika Horazna, Olga Babosova, Martina Vojtechova, Katerina Galuskova, Eva Sloncova, Vladimir Korinek
Publikováno v:
Genes, Vol 9, Iss 9, p 439 (2018)
T-cell factor 4 (TCF4), together with β-catenin coactivator, functions as the major transcriptional mediator of the canonical wingless/integrated (Wnt) signaling pathway in the intestinal epithelium. The pathway activity is essential for both intest
Externí odkaz:
https://doaj.org/article/2622cf48ec5546b0a45b665ba274ccd3
Autor:
Vitezslav Kriz, Vladimir Korinek
Publikováno v:
Genes, Vol 9, Iss 1, p 20 (2018)
In this review, we address aspects of Wnt, R-Spondin (RSPO) and Hippo signalling, in both healthy and transformed intestinal epithelium. In intestinal stem cells (ISCs), the Wnt pathway is essential for intestinal crypt formation and renewal, whereas
Externí odkaz:
https://doaj.org/article/86da43ec8d504146b340051a639dd2cb
Autor:
Vladimir Korinek, Petr Bartunek, Zbynek Zdrahal, Jindrich Jindrich, Olga Machonova, Vitezslav Kriz, Monika Horazna, Eva Sloncova, Michaela Krausova, Dietmar Gradl, Jitka Stancikova, Martina Vojtechova, Antonio R. Pombinho, Lucie Tumova
PDF file - 515KB, Supplementary Materials and Methods. Supplementary Figure S1. Densitometric analysis of western blots shown in Figs. 2D (A), 3C (B) and 4D (C). Supplementary Figure S2. Monensin suppresses Wnt signaling activated by TALEN-induced di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8711be6e574a82a73568181fdd1f47d
https://doi.org/10.1158/1535-7163.22499776.v1
https://doi.org/10.1158/1535-7163.22499776.v1
Autor:
Vladimir Korinek, Petr Bartunek, Zbynek Zdrahal, Jindrich Jindrich, Olga Machonova, Vitezslav Kriz, Monika Horazna, Eva Sloncova, Michaela Krausova, Dietmar Gradl, Jitka Stancikova, Martina Vojtechova, Antonio R. Pombinho, Lucie Tumova
The Wnt signaling pathway is required during embryonic development and for the maintenance of homeostasis in adult tissues. However, aberrant activation of the pathway is implicated in a number of human disorders, including cancer of the gastrointest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b5ad80d390450cfcc66779c4db350e
https://doi.org/10.1158/1535-7163.c.6536254
https://doi.org/10.1158/1535-7163.c.6536254
Autor:
Michael Welsh, Christer Betsholtz, Ying Sun, Erik Larsson, Jaroslav Mares, Björn Åkerblom, Gabriela Calounova, Guangxiang Zang, Vitezslav Kriz, Nina S. Funa
Supplementary Figure 3 from Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e635d92c8d24140a341f43303e49bfd
https://doi.org/10.1158/0008-5472.22379607.v1
https://doi.org/10.1158/0008-5472.22379607.v1
Autor:
Michael Welsh, Christer Betsholtz, Ying Sun, Erik Larsson, Jaroslav Mares, Björn Åkerblom, Gabriela Calounova, Guangxiang Zang, Vitezslav Kriz, Nina S. Funa
Supplementary Figure Legends 1-7 from Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e6713a04b4f5f72a1cfcc914efe0d1c
https://doi.org/10.1158/0008-5472.22379601.v1
https://doi.org/10.1158/0008-5472.22379601.v1
Autor:
Michael Welsh, Christer Betsholtz, Ying Sun, Erik Larsson, Jaroslav Mares, Björn Åkerblom, Gabriela Calounova, Guangxiang Zang, Vitezslav Kriz, Nina S. Funa
Supplementary Table 2 Legend from Dysfunctional Microvasculature as a Consequence of Shb Gene Inactivation Causes Impaired Tumor Growth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::061c6d5d9fb8d43d04c6ed2562c1a251
https://doi.org/10.1158/0008-5472.22379592.v1
https://doi.org/10.1158/0008-5472.22379592.v1
Autor:
Michael Welsh, Christer Betsholtz, Ying Sun, Erik Larsson, Jaroslav Mares, Björn Åkerblom, Gabriela Calounova, Guangxiang Zang, Vitezslav Kriz, Nina S. Funa
Shb (Src homology 2 protein B) is an adapter protein downstream of the vascular endothelial growth factor receptor receptor-2 (VEGFR-2). Previous experiments have suggested a role for Shb in endothelial cell function. Recently, the Shb gene was inact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd698ed6ec874da0761dd6556fe0476f
https://doi.org/10.1158/0008-5472.c.6499290.v1
https://doi.org/10.1158/0008-5472.c.6499290.v1