Diastereoselectivity in addition of nitrile-stabilized carbanions to Schiff bases and in subsequent alkylation reactions

Autor: Viteva, L., Gospodova, Tz., Stefanovsky, Y., Simova, S.

Publikováno v: In Tetrahedron 2005 61(24):5855-5865

4,6-diphenylpyridines as promising novel anti-influenza agents targeting the PA-PB1 protein-protein interaction: structure-activity relationships

Autor: Trist, I.M., Nannetti, G., Tintori, C., Fallacara, A.L., Deodato, D., Mercorrelli, B., Palu, G., Wijtmans, M., Gospodova, T., Edink, E.S., Verheij, M.H.P., de Esch, I.J.P., Viteva, L., Loregian, A., Botta, M.

Publikováno v: Trist, I M, Nannetti, G, Tintori, C, Fallacara, A L, Deodato, D, Mercorrelli, B, Palu, G, Wijtmans, M, Gospodova, T, Edink, E S, Verheij, M H P, de Esch, I J P, Viteva, L, Loregian, A & Botta, M 2016, ' 4,6-diphenylpyridines as promising novel anti-influenza agents targeting the PA-PB1 protein-protein interaction: structure-activity relationships. ', Journal of Medicinal Chemistry, vol. 59, no. 6, pp. 2688-2703 . https://doi.org/10.1021/acs.jmedchem.5b01935
Journal of Medicinal Chemistry, 59(6), 2688-2703. American Chemical Society

Influenza is an infectious disease that represents an important public health burden, with high impact on the global morbidity, mortality, and economy. The poor protection and the need of annual updating of the anti-influenza vaccine, added to the ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0bdd0767309d30e939e3b47fa5585b4a
https://hdl.handle.net/1871.1/9ef16829-9e47-4136-ac32-449182ae2590

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Kinetic asymmetric protonation as a stereochemistry determining step in the Michael addition of acetic acid derivatives to α-substituted cinnamic acid derivatives.

Autor: Viteva, L., Gorrichon, L.

Publikováno v: Chemical Monthly / Monatshefte für Chemie; 1995, Vol. 126 Issue 8/9, p1001-1009, 9p