Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Viter Márquez"'
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:472-480
Ketolides, the third generation of expanded-spectrum macrolides, have in the last years become a successful weapon in the endless war against macrolide-resistant pathogens. Ketolides are semisynthetic derivatives of the naturally produced macrolide e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2da85f0c61521ef233cfef1070e4bf33
https://doi.org/10.1128/aac.01994-13
https://doi.org/10.1128/aac.01994-13
Promiscuous behaviour of archaeal ribosomal proteins: Implications for eukaryotic ribosome evolution
Autor:
Georg J. Arnold, Michael Thomm, Elizabeth Villa, Viter Márquez, Roland Beckmann, Jean Paul Armache, Otto Berninghausen, Andreas M. Anger, Daniel N. Wilson, Thomas Fröhlich, Sibylle Franckenberg
Publikováno v:
Nucleic Acids Research
NUCLEIC ACIDS RESEARCH
NUCLEIC ACIDS RESEARCH
In all living cells, protein synthesis occurs on ribonucleoprotein particles called ribosomes. Molecular models have been reported for complete bacterial 70S and eukaryotic 80S ribosomes; however, only molecular models of large 50S subunits have been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f6a21e5fb355d27e6a4653d2e3049f7
http://europepmc.org/articles/PMC3553981
http://europepmc.org/articles/PMC3553981
Autor:
Viter Márquez, Barry S. Cooperman, Yuanwei Chen, Marina E. Ivanova, Hanqing Liu, Aleksandra Mikolajka, Agata L. Starosta, Daniel N. Wilson
Publikováno v:
Chemistry & Biology. 18:589-600
SummaryThe ribosome is a major target in the bacterial cell for antibiotics. Here, we dissect the effects that the thiopeptide antibiotics thiostrepton (ThS) and micrococcin (MiC) as well as the orthosomycin antibiotic evernimicin (Evn) have on trans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be74e509c267291161ba4a824af2743
https://doi.org/10.1016/j.chembiol.2011.03.010
https://doi.org/10.1016/j.chembiol.2011.03.010
Autor:
Daniel Sohmen, Thomas Fröhlich, Michael Thomm, Roland Beckmann, Viter Márquez, Aleksandra Mikolajka, Daniel N. Wilson, Alexandra Dönhöfer, Georg J. Arnold, Otto Berninghausen, Jean Paul Armache
Publikováno v:
Journal of Molecular Biology. 405:1215-1232
Protein synthesis occurs in macromolecular particles called ribosomes. All ribosomes are composed of RNA and proteins. While the protein composition of bacterial and eukaryotic ribosomes has been well-characterized, a systematic analysis of archaeal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be82d1c53bf2f3ae5a142f7885c4eefc
https://doi.org/10.1016/j.jmb.2010.11.055
https://doi.org/10.1016/j.jmb.2010.11.055
Autor:
Daniel N. Wilson, Alexandra Dönhöfer, Partha P. Datta, Paola Fucini, Viter Márquez, Manjuli R. Sharma, C. Barat, Rajendra K. Agrawal
Publikováno v:
Journal of Biological Chemistry. 285:4006-4014
Plastid-specific ribosomal proteins (PSRPs) have been proposed to play roles in the light-dependent regulation of chloroplast translation. Here we demonstrate that PSRP1 is not a bona fide ribosomal protein, but rather a functional homologue of the E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee165b25b20715de1decc71efdb0bb41
https://doi.org/10.1074/jbc.m109.062299
https://doi.org/10.1074/jbc.m109.062299
Autor:
Krista Trappl, Ronald Micura, Katja Fauster, Jessica Steger, Holger Moroder, Dagmar Graber, Viter Márquez, Norbert Polacek, Daniel N. Wilson
Publikováno v:
Angewandte Chemie International Edition. 48:4056-4060
Translation of specific small peptides on the ribosome can confer resistance to macrolide antibiotics. To reveal the molecular details of this and related phenomena, stable RNA-peptide conjugates that mimic peptidyl-tRNA would be desirable, especiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b780143bd1ef46bfe8da35308c4bd837
https://doi.org/10.1002/anie.200900939
https://doi.org/10.1002/anie.200900939
Publikováno v:
Cell. 118:45-55
Maintenance of the translation reading frame is one of the most remarkable achievements of the ribosome while decoding the information of an mRNA. Loss of the reading frame through spontaneous frameshifting occurs with a frequency of one in 30,000 am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a44e90db7b34db520435f4ca41fec529
https://doi.org/10.1016/j.cell.2004.06.012
https://doi.org/10.1016/j.cell.2004.06.012
Publikováno v:
Biochemical Society Transactions. 30:133-140
The ribosome translates the genetic information of an mRNA molecule into a sequence of amino acids. The ribosome utilizes tRNAs to connect elements of the RNA and protein worlds during protein synthesis, i.e. an anticodon as a unit of genetic informa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01e75bfb39ab517fa5267c92e832301d
https://doi.org/10.1042/bst0300133
https://doi.org/10.1042/bst0300133
Autor:
Sebastian Patzke, Markus A. Schäfer, Marylena Dabrowski, Edda Einfeldt, Gundo Diedrich, Ulrich Stelzl, Detlev Kamp, Knud H. Nierhaus, Christian M. T. Spahn, Viter Márquez, Gregor Blaha, Heinrich B. Stuhrmann, Regine Willumeit, Nils Burkhardt
This chapter provides a brief review of the reactions of the elongation cycle, and discusses recent data that clarify and explain some points of the divergent aspects of the current models of the elongation cycle. It shows that the location and the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c64119f502308778dd1d6860e4495c0
https://doi.org/10.1128/9781555818142.ch26
https://doi.org/10.1128/9781555818142.ch26
Publikováno v:
eLS
The initiation phase is the rate-limiting step in protein synthesis where messenger ribonucleic acid (mRNA), initiator-transfer RNA (tRNA) and ribosomal subunits are assembled together in the presence of specific initiation factors. This process is t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b2d9bcc0e42a650aa2ce7d96492fabc
https://doi.org/10.1002/9780470015902.a0021835
https://doi.org/10.1002/9780470015902.a0021835