Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Vitaly V Ganusov"'
Autor:
Louis J Gross, Rachel Patton McCord, Sondra LoRe, Vitaly V Ganusov, Tian Hong, W Christopher Strickland, David Talmy, Albrecht G von Arnim, Greg Wiggins
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284982 (2023)
Substantial guidance is available on undergraduate quantitative training for biologists, including reports focused on biomedical science. Far less attention has been paid to the graduate curriculum and the particular challenges of the diversity of sp
Externí odkaz:
https://doaj.org/article/45a865201e244e90a9e3856efbb2868c
Publikováno v:
PLoS Pathogens, Vol 16, Iss 5, p e1008181 (2020)
Plasmodium sporozoites are the infective stage of the malaria parasite. Though this is a bottleneck for the parasite, the quantitative dynamics of transmission, from mosquito inoculation of sporozoites to patent blood-stage infection in the mammalian
Externí odkaz:
https://doaj.org/article/7febb2f18f754b12b632930c442396a5
Autor:
Shunsuke Sakai, Keith D Kauffman, Michelle A Sallin, Arlene H Sharpe, Howard A Young, Vitaly V Ganusov, Daniel L Barber
Publikováno v:
PLoS Pathogens, Vol 12, Iss 5, p e1005667 (2016)
IFN-γ-producing CD4 T cells are required for protection against Mycobacterium tuberculosis (Mtb) infection, but the extent to which IFN-γ contributes to overall CD4 T cell-mediated protection remains unclear. Furthermore, it is not known if increas
Externí odkaz:
https://doaj.org/article/7f77a02e79c44c3fbea7435cc5c4fc21
Autor:
Sivan Leviyang, Vitaly V Ganusov
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004492 (2015)
Recent studies have highlighted the ability of HIV to escape from cytotoxic T lymphocyte (CTL) responses that concurrently target multiple viral epitopes. Yet, the viral dynamics involved in such escape are incompletely understood. Previous analyses
Externí odkaz:
https://doaj.org/article/30a304519bc8478e98b99e9cb767e38d
Autor:
Vitaly V Ganusov, Jeremy Auerbach
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 5, p e1003586 (2014)
The kinetics of recirculation of naive lymphocytes in the body has important implications for the speed at which local infections are detected and controlled by immune responses. With a help of a novel mathematical model, we analyze experimental data
Externí odkaz:
https://doaj.org/article/2443936b56cd4baab1187f0f1d376ee3
Publikováno v:
PLoS Computational Biology, Vol 10, Iss 1, p e1003414 (2014)
Johne's disease (JD), a persistent and slow progressing infection of ruminants such as cows and sheep, is caused by slow replicating bacilli Mycobacterium avium subspecies paratuberculosis (MAP) infecting macrophages in the gut. Infected animals init
Externí odkaz:
https://doaj.org/article/2350a37d38384cca9699d6efebc9088a
Autor:
Katharine J Bar, Chun-yen Tsao, Shilpa S Iyer, Julie M Decker, Yongping Yang, Mattia Bonsignori, Xi Chen, Kwan-Ki Hwang, David C Montefiori, Hua-Xin Liao, Peter Hraber, William Fischer, Hui Li, Shuyi Wang, Sarah Sterrett, Brandon F Keele, Vitaly V Ganusov, Alan S Perelson, Bette T Korber, Ivelin Georgiev, Jason S McLellan, Jeffrey W Pavlicek, Feng Gao, Barton F Haynes, Beatrice H Hahn, Peter D Kwong, George M Shaw
Publikováno v:
PLoS Pathogens, Vol 8, Iss 5, p e1002721 (2012)
Single genome sequencing of early HIV-1 genomes provides a sensitive, dynamic assessment of virus evolution and insight into the earliest anti-viral immune responses in vivo. By using this approach, together with deep sequencing, site-directed mutage
Externí odkaz:
https://doaj.org/article/3b0dc36fc26244f580f06b3696c32358
Autor:
Irina Yu Nikitina, Natalya A Kondratuk, George A Kosmiadi, Rasul B Amansahedov, Irina A Vasilyeva, Vitaly V Ganusov, Irina V Lyadova
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43733 (2012)
Effector CD4 T cells represent a key component of the host's anti-tuberculosis immune defense. Successful differentiation and functioning of effector lymphocytes protects the host against severe M. tuberculosis (Mtb) infection. On the other hand, eff
Externí odkaz:
https://doaj.org/article/ac7efb02161e404a844628d474c20afc
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e15959 (2011)
It has been difficult to correlate the quality of CD8 T cell responses with protection against viral infections. To investigate the relationship between efficacy and magnitude of T cell responses, we quantify the rate at which individual CD8 effector
Externí odkaz:
https://doaj.org/article/ca1408034bb8405283101b7a557f8725
Publikováno v:
PLoS ONE, Vol 5, Iss 9 (2010)
Quantitative understanding of the kinetics of lymphocyte proliferation and death upon activation with an antigen is crucial for elucidating factors determining the magnitude, duration and efficiency of the immune response. Recent advances in quantita
Externí odkaz:
https://doaj.org/article/500c31617e144e2d98c04f7d89b56b14