Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Vitaly O Kheyfets"'
Autor:
Sebastian Laudenschlager, Samuel Schofield, Nicolas Drysdale, Matthew Stone, Jennifer Romanowicz, Benjamin Frank, Michael DiMaria, Vitaly O Kheyfets, Mehdi Hedjazi-Moghari
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0307890 (2024)
Children with single ventricle heart disease typically require a series of three operations, (1) Norwood, (2) Glenn, and (3) Fontan, which ultimately results in complete separation of the pulmonary and systemic circuits to improve pulmonary/systemic
Externí odkaz:
https://doaj.org/article/7d87c3e7bd634d21991e5c9f16d95bf9
Autor:
Kenzo Ichimura, Everton J. Santana, Tatiana Kuznetsova, Nicholas Cauwenberghs, František Sabovčik, Lindsey Chun, Nadia L. C. Francisco, Vitaly O. Kheyfets, Michael Salerno, Roham T. Zamanian, Edda Spiekerkoetter, Francois Haddad
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Ventricular interdependence plays an important role in pulmonary arterial hypertension (PAH). It can decrease left ventricular (LV) longitudinal strain (LVLS) and lead to a leftward displacement (“transverse shortening”) of the intervent
Externí odkaz:
https://doaj.org/article/ceb037b5b1b24ce69981ecca0e5d4165
Autor:
Vitaly O. Kheyfets, Andrew J. Sweatt, Mardi Gomberg-Maitland, Dunbar D. Ivy, Robin Condliffe, David G. Kiely, Allan Lawrie, Bradley A. Maron, Roham T. Zamanian, Kurt R. Stenmark
Publikováno v:
ERJ Open Research, Vol 9, Iss 1 (2023)
Background Pulmonary arterial hypertension (PAH) is a heterogeneous and complex pulmonary vascular disease associated with substantial morbidity. Machine-learning algorithms (used in many PAH risk calculators) can combine established parameters with
Externí odkaz:
https://doaj.org/article/0f45d5cc732d4dd089f3f50bc3a69539
Autor:
Vitaly O. Kheyfets, Sushil Kumar, Paul M. Heerdt, Kenzo Ichimura, R. Dale Brown, Melissa Lucero, Ilham Essafri, Sarah Williams, Kurt R. Stenmark, Edda Spiekerkoetter
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9746 (2023)
This study analyzed microarray data of right ventricular (RV) tissue from rats exposed to pulmonary embolism to understand the initial dynamic transcriptional response to mechanical stress and compare it with experimental pulmonary hypertension (PH)
Externí odkaz:
https://doaj.org/article/9549028ed3b4470aacdd65060e741a63
Autor:
Melanie J. Dufva, Mario Boehm, Kenzo Ichimura, Uyen Truong, Xulei Qin, Jennifer Tabakh, Kendall S. Hunter, Dunbar Ivy, Edda Spiekerkoetter, Vitaly O. Kheyfets
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-14 (2021)
Abstract Background The role of interventricular mechanics in pediatric pulmonary arterial hypertension (PAH) and its relation to right ventricular (RV) dysfunction has been largely overlooked. Here, we characterize the impact of maintained pressure
Externí odkaz:
https://doaj.org/article/03a5063cd8724511a0bdf3116bd5b1f8
Autor:
Brice V. McConnell, Eugene Kronberg, Lindsey M. Medenblik, Vitaly O. Kheyfets, Alberto R. Ramos, Stefan H. Sillau, Rachelle L. Pulver, Brianne M. Bettcher
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Slow wave activity (SWA) during sleep is associated with synaptic regulation and memory processing functions. Each cycle of non-rapid-eye-movement (NREM) sleep demonstrates a waxing and waning amount of SWA during the transitions between stages N2 an
Externí odkaz:
https://doaj.org/article/49b2d281258f4ad194ff9377d5b4cbb2
Autor:
R. Dale Brown, Kendall S. Hunter, Min Li, Maria G. Frid, Julie Harral, Greta M. Krafsur, Timothy N. Holt, Jason Williams, Hui Zhang, Suzette R. Riddle, Michael G. Edwards, Sushil Kumar, Cheng-Jun Hu, Brian B. Graham, Lori A. Walker, Franklyn B. Garry, Peter M. Buttrick, Tim Lahm, Vitaly O. Kheyfets, Kirk C. Hansen, Kurt R. Stenmark
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 324:H804-H820
Using a large animal model and employing a comprehensive approach integrating hemodynamic, transcriptomic, proteomic, and immunohistochemical analyses, we examined the early (2 wk) effects of severe PH on the RV. We observed that RV remodeling during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e426dd05eb030a8846d9667ad5f8d584
https://doi.org/10.1152/ajpheart.00614.2022
https://doi.org/10.1152/ajpheart.00614.2022
Autor:
Sue Gu, Khushboo Goel, Lindsay M. Forbes, Vitaly O. Kheyfets, Yen‐rei A. Yu, Rubin M. Tuder, Kurt R. Stenmark
Publikováno v:
Comprehensive Physiology. :4295-4319
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7829cff2594fb3eebea75a70c5a337d0
https://doi.org/10.1002/cphy.c220010
https://doi.org/10.1002/cphy.c220010
Autor:
Vitaly O. Kheyfets, Melanie J. Dufva, Mario Boehm, Xuefeit Tian, Xulei Qin, Jennifer E. Tabakh, Uyen Truong, Dunbar Ivy, Edda Spiekerkoetter
Publikováno v:
Physiological Reports, Vol 8, Iss 9, Pp n/a-n/a (2020)
Abstract Pulmonary hypertension (PH) results in right ventricular (RV) pressure overload and eventual failure. Current research efforts have focused on the RV while overlooking the left ventricle (LV), which is responsible for mechanically assisting
Externí odkaz:
https://doaj.org/article/8c69f12b589d4b0b9feb84f2a5c5a937
Autor:
Vitaly O. Kheyfets, Andrew J. Sweatt, Mardi Gomberg-Maitland, Dunbar D. Ivy, Robin Condliffe, David G. Kiely, Allan Lawrie, Bradley A. Maron, Roham T. Zamanian, Kurt R. Stenmark
Publikováno v:
ERJ Open Research. 9:00484-2022
BackgroundPulmonary arterial hypertension (PAH) is a heterogeneous and complex pulmonary vascular disease associated with substantial morbidity. Machine-learning algorithms (used in many PAH risk calculators) can combine established parameters with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::93fc93eae8feb255c00f65960632c153
https://doi.org/10.1183/23120541.00484-2022
https://doi.org/10.1183/23120541.00484-2022