Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Vitaly A. Roginsky"'
Autor:
Antonina V. Pustovidko, Lidia V. Domnina, Ruben A. Simonyan, Boris V. Chernyak, Natalia V. Sumbatyan, Vitaly A. Roginsky, Galina A. Korshunova, Maxim V. Skulachev, Vladimir P. Skulachev, Tatyana I. Rokitskaya, Yuriy N. Antonenko, Konstantin G. Lyamzaev, O. Y. Ivanova, Vadim N. Tashlitsky, Inna I. Severina
Publikováno v:
Pharmaceutical Research. 28:2883-2895
To develop effective mitochondria-targeted antioxidants composed entirely of natural constituents.Novel mitochondria-targeted antioxidants were synthesized containing plant electron carrier and antioxidant plastoquinone conjugated by nonyloxycarbonyl
Autor:
Vitaly A. Roginsky, Konstantin G. Lyamzaev, Nataliya G. Kolosova, M. V. Egorov, Vladimir A. Chistyakov, T. P. Shkurat, Dmitry A. Cherepanov, Vladimir N. Anisimov, Vadim N. Tashlitsky, Dmitry B. Zorov, Maxim V. Skulachev, Fedor F. Severin, K. M. Shidlovsky, Yuri N. Antonenko, Galina A. Korshunova, Inna I. Severina, Egor Y. Plotnikov, A. Y. Savchenko, Mikhail Yu. Vyssokikh, Vladimir P. Skulachev, Boris V. Chernyak, Andrey A. Zamyatnin
Publikováno v:
ResearcherID
Plastoquinone, a very effective electron carrier and antioxidant of chloroplasts, was conjugated with decyltriphenylphosphonium to obtain a cation easily penetrating through membranes. This cation, called SkQ1, is specifically targeted to mitochondri
Publikováno v:
European Journal of Lipid Science and Technology. 112:887-893
A technique based on monitoring oxygen consumption was applied to study 11 natural and model polyphenols (PP, QH 2 ) as well as four typical monophenolics as a chain-breaking antioxidant during the controlled chain oxidation of methyl linoleate (ML)
Autor:
Renata A. Zvyagilskaya, Ludmila S. Khailova, Fedor F. Severin, Vadim N. Tashlitsky, Mikhail Yu. Vyssokikh, Maxim V. Skulachev, Yury N. Antonenko, S.S. Klishin, Olga Yu. Pletjushkina, Konstantin G. Lyamzaev, T. A. Trendeleva, Tatiana I. Rokitskaya, Galina A. Korshunova, D. S. Izyumov, Boris V. Chernyak, Natalia V. Sumbatyan, Vladimir P. Skulachev, Ruben A. Simonyan, Dmitry A. Cherepanov, Vitaly A. Roginsky, E. I. Sukhanova, Inna I. Severina
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1797(6-7):878-889
The present state of the art in studies on the mechanisms of antioxidant activities of mitochondria-targeted cationic plastoquinone derivatives (SkQs) is reviewed. Our experiments showed that these compounds can operate as antioxidants in two quite d
Autor:
Vitaly A. Roginsky
Publikováno v:
Chemistry and Physics of Lipids. 163:127-130
The kinetics of the chain free-radical oxidation of cardiolipin (CL), a unique phospholipid containing four linoleate moieties, have been studied for the first time. The technique based on monitoring oxygen consumption by using a Clark electrode was
Publikováno v:
Aging (Albany NY)
The chain-breaking antioxidant activities of reduced form of novel type of geroprotectors, mitochondria-targeted quinones (QH(2)) have quantitatively been measured for the first time. To this end, the chain peroxidation of methyl linoleate (ML) in Tr
Publikováno v:
International Journal of Chemical Kinetics. 41:92-100
The technique based on monitoring oxygen consumption was applied to test 18 polyphenols (PP) and model phenolics as a chain-breaking antioxidant during the oxidation of styrene initiated by 2,2′-azobis(2,4-dimethylvaleronitril) at 37°C. The chain-
Publikováno v:
Journal of Agricultural and Food Chemistry. 55:6798-6806
A new quantitative approach to investigate the capability of iron heme complexes (HEM), metmyoglobin and hemin, to catalyze lipid peroxidation was elaborated. The oxidation of methyl linoleate in micellar solutions was used as a testing model. The ke
Autor:
Dalene de Beer, James F. Harbertson, Douglas O. Adams, Tatyana Barsukova, Paul A. Kilmartin, Vitaly A. Roginsky
Publikováno v:
Journal of the Science of Food and Agriculture. 86:834-840
A range of physico-chemical properties of 21 Californian red wines from 1 to 28 years old were correlated with wine age. The level of monomeric phenolics and low molecular-weight phenolic oligomers decreased with age, while the level of high molecula
Autor:
Vitaly A. Roginsky, Eduardo Lissi
Publikováno v:
Food Chemistry. 92:235-254
The beneficial influence of many foodstuffs and beverages including fruits, vegetables, tea, red wine, coffee, and cacao on human health has been recently recognized to originate from the chain-breaking antioxidant activity (AOA) of natural polypheno