Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Vitaly A Selivanov"'
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0255164 (2021)
Glutamate plays diverse roles in neuronal cells, affecting cell energetics and reactive oxygen species (ROS) generation. These roles are especially vital for neuronal cells, which deal with high amounts of glutamate as a neurotransmitter. Our analysi
Externí odkaz:
https://doaj.org/article/132b72ebbd48489eb75471206dbbee4c
Autor:
Carles Foguet, Anusha Jayaraman, Silvia Marin, Vitaly A Selivanov, Pablo Moreno, Ramon Messeguer, Pedro de Atauri, Marta Cascante
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 9, p e1007310 (2019)
Deciphering the mechanisms of regulation of metabolic networks subjected to perturbations, including disease states and drug-induced stress, relies on tracing metabolic fluxes. One of the most informative data to predict metabolic fluxes are 13C base
Externí odkaz:
https://doaj.org/article/38ccba5ca8b544d3a07053b25f40e4fd
Autor:
Carles Foguet, Silvia Marin, Vitaly A Selivanov, Eric Fanchon, Wai-Nang Paul Lee, Joan J Guinovart, Pedro de Atauri, Marta Cascante
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 4, p e1004899 (2016)
The liver performs many essential metabolic functions, which can be studied using computational models of hepatocytes. Here we present HepatoDyn, a highly detailed dynamic model of hepatocyte metabolism. HepatoDyn includes a large metabolic network,
Externí odkaz:
https://doaj.org/article/590fe85107d54419aa985020ca776596
Autor:
Vitaly A Selivanov, Marta Cascante, Mark Friedman, Mark F Schumaker, Massimo Trucco, Tatyana V Votyakova
Publikováno v:
PLoS Computational Biology, Vol 8, Iss 9, p e1002700 (2012)
The mitochondrial electron transport chain transforms energy satisfying cellular demand and generates reactive oxygen species (ROS) that act as metabolic signals or destructive factors. Therefore, knowledge of the possible modes and bifurcations of e
Externí odkaz:
https://doaj.org/article/2e499935181f4a61919cc4248009c2d4
Autor:
Vitaly A Selivanov, Tatyana V Votyakova, Violetta N Pivtoraiko, Jennifer Zeak, Tatiana Sukhomlin, Massimo Trucco, Josep Roca, Marta Cascante
Publikováno v:
PLoS Computational Biology, Vol 7, Iss 3, p e1001115 (2011)
Reactive oxygen species (ROS) produced in the mitochondrial respiratory chain (RC) are primary signals that modulate cellular adaptation to environment, and are also destructive factors that damage cells under the conditions of hypoxia/reoxygenation
Externí odkaz:
https://doaj.org/article/e46d90fe41af4a36ab5ae3fbecd6f951
Autor:
Vitaly A Selivanov, Tatyana V Votyakova, Jennifer A Zeak, Massimo Trucco, Josep Roca, Marta Cascante
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 12, p e1000619 (2009)
Increased production of reactive oxygen species (ROS) in mitochondria underlies major systemic diseases, and this clinical problem stimulates a great scientific interest in the mechanism of ROS generation. However, the mechanism of hypoxia-induced ch
Externí odkaz:
https://doaj.org/article/b353c157fd9a43da8d0e6b4696235dca
Autor:
Vitaly A, Selivanov, Olga A, Zagubnaya, Carles, Foguet, Yaroslav R, Nartsissov, Marta, Cascante
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2399
Mitochondrial respiratory chain (RC) transforms the reductive power of NADH or FADH2 oxidation into a proton gradient between the matrix and cytosolic sides of the inner mitochondrial membrane, that ATP synthase uses to generate ATP. This process con
Autor:
Vitaly A. Selivanov, Olga A. Zagubnaya, Carles Foguet, Yaroslav R. Nartsissov, Marta Cascante
Publikováno v:
Methods in Molecular Biology ISBN: 9781071618301
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b24884e100b2f7f0daa78c3c3caceaa5
https://doi.org/10.1007/978-1-0716-1831-8_6
https://doi.org/10.1007/978-1-0716-1831-8_6
Autor:
Carles Foguet, Vitaly A. Selivanov, Rotem Katzir, Marta Cascante, Philippe Sabatier, Eytan Ruppin, Shir Katz, Ibrahim H. Polat, Michal Harel, Tamar Geiger
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Scientific Reports
Dipòsit Digital de la UB
Universidad de Barcelona
Altered metabolism is a hallmark of cancer, but little is still known about its regulation. In this study, we measure transcriptomic, proteomic, phospho-proteomic and fluxomics data in a breast cancer cell-line (MCF7) across three different growth co
Publikováno v:
Molecular Catalysis. 466:122-129
For baker’s yeast transketolase (TK), cooperative binding of thiamine diphosphate (ThDP) and substrates in the transferase reaction is known. We show here that the differences in the properties of the active centers of TK are formed already upon th