Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Vitaliy Gavrilyuk"'
Autor:
Alessandra Spagnolo, Candan A Akar, Sergey Kalinin, Vitaliy Gavrilyuk, Guy L. Weinberg, Douglas L. Feinstein
Publikováno v:
The Open Cancer Immunology Journal. 3:36-40
Thiazodinedione (TZD) agonists of the peroxisome proliferator activated receptor gamma (PPAR) exert metabolic effects in glial cells. In primary astrocytes, TZDs are cytoprotective and have anti-inflammatory actions; in contrast, in glioma cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::315b89dc700958b422d302a3a92cb886
https://doi.org/10.2174/1876401001003010036
https://doi.org/10.2174/1876401001003010036
Autor:
Michael T. Heneka, Robert Vasser, Vitaliy Gavrilyuk, Douglas L. Feinstein, Paul E. Polak, Sergey Kalinin, Jie Zhao
Publikováno v:
Neurobiology of Aging. 28:1206-1214
Loss of Locus coeruleus (LC) noradrenergic (NA) neurons occurs in several neurodegenerative conditions including Alzheimer's disease (AD). In vitro and in vivo studies have shown that NA influences several features of AD disease including inflammatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::441f26bf2ce35987783b5f49f247457e
https://doi.org/10.1016/j.neurobiolaging.2006.06.003
https://doi.org/10.1016/j.neurobiolaging.2006.06.003
Publikováno v:
Journal of Neurochemistry. 99:1389-1402
Brain abscesses arise from a focal parenchymal infection by various pathogens, particularly Staphylococcus aureus. We have shown that astrocytes are activated upon exposure to S. aureus and may contribute to the excessive tissue damage characteristic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841c57d4571a1b75c3475feb60cbcd59
https://doi.org/10.1111/j.1471-4159.2006.04183.x
https://doi.org/10.1111/j.1471-4159.2006.04183.x
Publikováno v:
Antioxidants & Redox Signaling. 8:885-892
The authors previously showed that conditioned media (CM) from activated microglia increased inducible nitric oxide synthase (NOS2) in cortical neurons. Here they examined the ability of noradrenaline (NA) to reduce neuronal NOS2 or cell death. Prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdc9e7fcb2becbad4802fe9391c9d1d4
https://doi.org/10.1089/ars.2006.8.885
https://doi.org/10.1089/ars.2006.8.885
Autor:
Andrew Middlecamp, Dale A. Pelligrino, Sergey Kalinin, Susan O. McGuire, Douglas L. Feinstein, Brian S. Hilbush, Vitaliy Gavrilyuk, Guy L. Weinberg
Publikováno v:
Journal of Neurochemistry. 92:1140-1149
Brain inflammation is regulated by endogenous substances, including neurotransmitters such as noradrenaline (NA), which can increase anti-inflammatory genes. To identify NA-regulated, anti-inflammatory genes, we used TOGA (total gene expression analy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7b4e1f735d17efe0ec3d1103cd12b64
https://doi.org/10.1111/j.1471-4159.2004.02942.x
https://doi.org/10.1111/j.1471-4159.2004.02942.x
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 286:H2020-H2027
Multidrug resistance protein 5 (MRP5) has been linked to cGMP cellular export in peripheral vascular smooth muscle cells (VSMCs) and is widely expressed in brain vascular tissue. In the present study, we examined whether knockdown of MRP5 in pial art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ca6b47c03bfba41fb15c8256ea475f
https://doi.org/10.1152/ajpheart.01105.2003
https://doi.org/10.1152/ajpheart.01105.2003
Autor:
M. Kerry O'Banion, Vitaliy Gavrilyuk, Gary E. Landreth, Guy L. Weinberg, Douglas L. Feinstein, Michael T. Heneka
Publikováno v:
Journal of Neurochemistry. 85:387-398
The inflammatory responses in many cell types are reduced by noradrenaline (NA) binding to β-adrenergic receptors. We previously demonstrated that cortical inflammatory responses to aggregated amyloid beta (Aβ) are increased if NA levels were first
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7b6bffb3eefb095c58da18029bb605f
https://doi.org/10.1046/j.1471-4159.2003.01694.x
https://doi.org/10.1046/j.1471-4159.2003.01694.x
Autor:
Vitaliy Gavrilyuk, Juan P. Bolaños, June W. Palmer, Guy L. Weinberg, Dale A. Pelligrino, Cinzia Dello Russo, Douglas L. Feinstein, Elena Galea, Angeles Almeida
Publikováno v:
Journal of Biological Chemistry. 278:5828-5836
Activation of peroxisome proliferator-activated receptors (PPARs) can regulate brain physiology and provide protection in models of neurological disease; however, neither their exact targets nor mechanisms of action in brain are known. In many cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704c15157e26413232862c9dbbe30e9b
https://doi.org/10.1074/jbc.m208132200
https://doi.org/10.1074/jbc.m208132200
Autor:
Dale A. Pelligrino, Cinzia Dello Russo, Michael T. Heneka, Douglas L. Feinstein, Vitaliy Gavrilyuk, Guy L. Weinberg
Publikováno v:
Journal of Biological Chemistry. 277:29662-29668
The neurotransmitter norepinephrine (NE) can inhibit inflammatory gene expression in glial cells; however, the mechanisms involved are not clear. In primary astrocytes, NE dose-dependently increased the expression of inhibitory IκBα protein accompa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bb82f96a597b19244046f11167e92e1
https://doi.org/10.1074/jbc.m203256200
https://doi.org/10.1074/jbc.m203256200
Autor:
Cinzia Dello Russo, Vitaliy Gavrilyuk, Michael T. Heneka, Aigang Lu, Frank R. Sharp, Guy L. Weinberg, Patricia Murphy, Anthony Sharp, Douglas L. Feinstein, Joseph Shin
Publikováno v:
Journal of Neuroscience Research. 67:461-470
The production of nitric oxide by the inflammatory isoform of nitric oxide synthase (NOS2) in brain glial cells is thought to contribute to the causes and development of neurological diseases and trauma. We previously demonstrated that activation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::662e497e9d75db7aedbdaa0c3472b479
https://doi.org/10.1002/jnr.10139
https://doi.org/10.1002/jnr.10139