Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Vitalina Bodenko"'
Autor:
Ayman Abouzayed, Kamila Seitova, Fanny Lundmark, Vitalina Bodenko, Maryam Oroujeni, Vladimir Tolmachev, Ulrika Rosenström, Anna Orlova
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionProstate specific membrane antigen (PSMA), highly expressed in metastatic castration-resistant prostate cancer (mCRPC), is an established therapeutic target. Theranostic PSMA-targeting agents are widely used in patient management and has
Externí odkaz:
https://doaj.org/article/f29b75a246594fe3adfa12541146a888
Autor:
Lutfi A. Hasnowo, Maria S. Larkina, Evgenii Plotnikov, Vitalina Bodenko, Feruza Yuldasheva, Elena Stasyuk, Stanislav A. Petrov, Nikolai Y. Zyk, Aleksei E. Machulkin, Nikolai I. Vorozhtsov, Elena K. Beloglazkina, Valentine G. Nenajdenko, Vladimir Tolmachev, Anna Orlova, Alexander G. Majouga, Mekhman S. Yusubov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 15, p 12206 (2023)
Prostate-specific membrane antigen (PSMA) has been identified as a target for the development of theranostic agents. In our current work, we describe the design and synthesis of novel N-[N-[(S)-1,3-dicarboxypropyl]carbamoyl]-(S)-L-lysine (DCL) urea-b
Externí odkaz:
https://doaj.org/article/81f624575912490ba329b31e7c819940
Autor:
Vladimir Tolmachev, Vitalina Bodenko, Maryam Oroujeni, Sergey Deyev, Elena Konovalova, Alexey Schulga, Sarah Lindbo, Sophia Hober, Olga Bragina, Anna Orlova, Anzhelika Vorobyeva
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15181 (2022)
Non-invasive radionuclide molecular visualization of human epidermal growth factor receptor type 2 (HER2) can provide stratification of patients for HER2-targeting therapy. This method can also enable monitoring of the response to such therapies, the
Externí odkaz:
https://doaj.org/article/1993c20ee1914f64be505194cea7d552
Autor:
Yongsheng Liu, Rezan Güler, Yunqi Liao, Anzhelika Vorobyeva, Olof Widmark, Theodorus J. Meuleman, Anna Koijen, Leendert J. van den Bos, Robert Naasz, Vitalina Bodenko, Anna Orlova, Caroline Ekblad, Vladimir Tolmachev, Fredrik Y. Frejd
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2519 (2022)
Targeted molecular radiation therapy is a promising emerging treatment modality in oncology, and peptide synthesis may shorten the time to reach the clinical stage. In this study, we have explored Chemo-Enzymatic Peptide Synthesis, or CEPS, as a new
Externí odkaz:
https://doaj.org/article/e10c627d9b1e4eb1b8464aefeb01cc56
Autor:
Yongsheng Liu, Shengze Yu, Tianqi Xu, Vitalina Bodenko, Anna Orlova, Maryam Oroujeni, Sara S. Rinne, Vladimir Tolmachev, Anzhelika Vorobyeva, Torbjörn Gräslund
Publikováno v:
Pharmaceutics, Vol 14, Iss 7, p 1475 (2022)
The Insulin-like growth factor-1 receptor (IGF-1R) is a molecular target for several monoclonal antibodies undergoing clinical evaluation as anticancer therapeutics. The non-invasive detection of IGF-1R expression in tumors might enable stratificatio
Externí odkaz:
https://doaj.org/article/763389a92a5e486a9d66ef663045a10a
Autor:
Tianqi Xu, Jie Zhang, Maryam Oroujeni, Maria S. Tretyakova, Vitalina Bodenko, Mikhail V. Belousov, Anna Orlova, Vladimir Tolmachev, Anzhelika Vorobyeva, Torbjörn Gräslund
Publikováno v:
Pharmaceutics, Vol 14, Iss 3, p 522 (2022)
Targeted drug conjugates based on Affibody molecules fused to an albumin-binding domain (ABD) for half-life extension have demonstrated potent anti-tumor activity in preclinical therapeutic studies. Furthermore, optimization of their molecular design
Externí odkaz:
https://doaj.org/article/8d7be3e34fd5413c88dd4af0a99c2e35
Comparison of HER2-targeted affibody conjugates loaded with auristatin- and maytansine-derived drugs
Autor:
Wen Yin, Tianqi Xu, Haozhong Ding, Jie Zhang, Vitalina Bodenko, Maria S. Tretyakova, Mikhail V. Belousov, Yongsheng Liu, Maryam Oroujeni, Anna Orlova, Vladimir Tolmachev, Torbjörn Gräslund, Anzhelika Vorobyeva
Publikováno v:
Journal of Controlled Release. 355:515-527
Autor:
Yongsheng Liu, Tianqi Xu, Anzhelika Vorobyeva, Annika Loftenius, Vitalina Bodenko, Anna Orlova, Fredrik Y. Frejd, Vladimir Tolmachev
Publikováno v:
Cancers; Volume 15; Issue 9; Pages: 2409
Affibody molecules are artificial proteins that can recognize cancer-related molecular abnormalities in the living body. Clinical studies demonstrated that Affibody molecules can be successfully used for radionuclide diagnostics. Targeted radionuclid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b4ce15d7b3d9b9b3fd53bd4749d0eab
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-502522
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-502522
Autor:
Vorobyeva, Vladimir Tolmachev, Vitalina Bodenko, Maryam Oroujeni, Sergey Deyev, Elena Konovalova, Alexey Schulga, Sarah Lindbo, Sophia Hober, Olga Bragina, Anna Orlova, Anzhelika
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 23; Pages: 15181
Non-invasive radionuclide molecular visualization of human epidermal growth factor receptor type 2 (HER2) can provide stratification of patients for HER2-targeting therapy. This method can also enable monitoring of the response to such therapies, the
Autor:
Vladimir, Tolmachev, Vitalina, Bodenko, Anna, Orlova, Alexey, Schulga, Sergey M, Deyev, Anzhelika, Vorobyeva
Publikováno v:
Oncology letters. 25(1)
The upregulation of epithelial cell adhesion molecule (EpCAM) expression, found in a substantial fraction of renal cell carcinomas (RCCs), renders it a potential molecular target for the treatment of disseminated RCC. However, the heterogeneous expre