Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Vita Ignatovica"'
Autor:
Nathalie Bringeland, Mathias Rask-Andersen, Helgi B. Schiöth, C Marcus, Yannis Manios, L A Hedberg, George Moschonis, Adam Ameur, S Juhlin, George P. Chrousos, Janis Klovins, Ulf Gyllensten, Vita Ignatovica, Ineta Kalnina, Robert Fredriksson, M Sällman Almén, Josefin A. Jacobsson
Publikováno v:
International Journal of Obesity (2005)
Background: The Fat mass and obesity-associated gene (FTO) was the first gene reliably associated with body mass index in genome-wide association studies on a population level. At present, the genetic variations within the FTO gene are still the comm
Publikováno v:
FEBS Journal. 279:180-191
The purinergic 12 receptor (P2Y12) is a major drug target for anticoagulant therapies, but little is known about the regions involved in ligand binding and activation of this receptor. We generated four randomized P2Y12 libraries and investigated the
Autor:
Gustavs Latkovskis, Janis Klovins, Helgi B. Schiöth, Andrejs Erglis, Raitis Peculis, Iveta Vaivade, Kaspars Megnis, Vita Ignatovica, Davids Fridmanis, Valdis Pirags
Publikováno v:
Molecular Biology Reports. 39:1917-1925
The purinergic 1 receptor (P2RY1) has been implicated in development of heart disease and in individual pharmacodynamic response to anticoagulant therapies. However, the association of polymorphisms in the P2RY1 gene with myocardial infarction (MI),
Publikováno v:
Open Life Sciences, Vol 6, Iss 2, Pp 167-175 (2011)
The melanocortin 4 receptor (MC4R) is involved in the regulation of energy homeostasis and is known as one of the major hypothalamic regulators of food intake. Several studies have shown that replacement of aspartic acid at position 126 of the MC4R a
Publikováno v:
The FEBS journal. 279(1)
The purinergic 12 receptor (P2Y12) is a major drug target for anticoagulant therapies, but little is known about the regions involved in ligand binding and activation of this receptor. We generated four randomized P2Y12 libraries and investigated the