Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Viswanatha Krishnakumari"'
Publikováno v:
ACS Omega, Vol 5, Iss 12, Pp 6366-6375 (2020)
Externí odkaz:
https://doaj.org/article/ef8f13cc84fe44c9b300118d6f4ba798
Autor:
Sravani Polepalli, Richa Singh, Shoma Naskar, Pasupuleti SKDB Punyasri, Kongari Ranjith Kumar, Kameshwari Yele, Viswanatha Krishnakumari, Raman Bakthisaran, Dipty Jain, Giriraj Ratan Chandak, Swasti Raychaudhuri
Publikováno v:
Journal of Proteins and Proteomics. 13:205-218
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e501c9b1d609b7b14086f08069e51c34
https://doi.org/10.1007/s42485-022-00096-z
https://doi.org/10.1007/s42485-022-00096-z
Publikováno v:
Chemical Biology & Drug Design. 92:1504-1513
Analogs of the cationic C-terminal segments of human-β-defensins HBD1-3, Phd1-3 with a single disulfide bond, exhibited comparable antimicrobial activity that was salt sensitive. They did not show hemolytic activity. In this study, N-terminal myrist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd28bdb9f88d9bc187d40b5f5f274e82
https://doi.org/10.1111/cbdd.13317
https://doi.org/10.1111/cbdd.13317
Publikováno v:
Antimicrobial Agents and Chemotherapy. 53:256-260
The activities of defensins HBD-1, HBD-2, and HBD-3 and their C-terminal analogs Phd1, Phd2, and Phd3 against Candida albicans were investigated. Phd1 to Phd3 showed lower-level activities than HBD-1 to HBD-3, although metabolic inhibitors did not re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158e856776e3f08ca32385c7f8efac73
https://doi.org/10.1128/aac.00470-08
https://doi.org/10.1128/aac.00470-08
Autor:
Ajit C. Kunwar, Ramakrishnan Nagaraj, Tushar Kanti Chakraborty, Dipankar Koley, Rapolu Ravi, Viswanatha Krishnakumari
Publikováno v:
The Journal of Organic Chemistry. 73:8731-8744
Sugar amino acid based 24-membered macrocyclic C2-symmetric cationic peptides were designed and synthesized. The cationic group was introduced in the sugar amino acids. The conformation of these cyclic compounds was ascertained through NMR techniques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4930d6052d84981878972fe49377bda6
https://doi.org/10.1021/jo801123q
https://doi.org/10.1021/jo801123q
Publikováno v:
Peptides. 27:2607-2613
The antibacterial activities of synthetic human β-defensin analogs, constrained by a single disulfide bridge and in the reduced form, have been investigated. The peptides span the carboxy-terminal region of human β-defensins (HBD-1–3), which have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51ff3a3a4906656c40b3baa661383cc6
https://doi.org/10.1016/j.peptides.2006.06.004
https://doi.org/10.1016/j.peptides.2006.06.004
Publikováno v:
Biochemistry. 42:9307-9315
Mammalian defensins (alpha as well as beta forms) have a beta-hairpin structural motif spanning approximately 20 residues at the carboxy-terminal end. We have investigated the antibacterial activity and biophysical properties of synthetic peptides co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8da21fe4cc005c19ee2f00585385776
https://doi.org/10.1021/bi034403y
https://doi.org/10.1021/bi034403y
Publikováno v:
Biophysical chemistry. 199
Peptides spanning the C-terminal segment of bovine-β-defensin-2 (BNBD-2) rich in cationic amino acids, show antimicrobial activity. However, they exhibit considerably reduced activity at physiological concentration of NaCl. In the present study, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf878e7a339a16d82c8169a0911fd866
https://pubmed.ncbi.nlm.nih.gov/25791057
https://pubmed.ncbi.nlm.nih.gov/25791057
Publikováno v:
The Journal of Peptide Research. 54:528-535
The effect of introducing a disulfide bridge between the N- and C-terminal ends on the structure and biological activities of the 13-residue linear peptide PKLLKTFLSKWIG(SPFK), which has both antibacterial and hemolytic activity, have been investigat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c2a49b696244fe9a6453b780d2fca833
https://doi.org/10.1034/j.1399-3011.1999.00133.x
https://doi.org/10.1034/j.1399-3011.1999.00133.x
Publikováno v:
FEMS microbiology letters. 348(1)
Human-β-defensins 1-3 (HBD-1-3) and their C-terminal analogs Phd-1-3 do not show antibacterial activity against Escherichia coli in the presence of mono- and divalent cations. Activity of peptides was examined against E. coli pretreated with carbony
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::417db6ded8005cfcd1c3c3f1315f9439
https://pubmed.ncbi.nlm.nih.gov/23980689
https://pubmed.ncbi.nlm.nih.gov/23980689