Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Viswanadham Sridhara"'
Autor:
Colin W. Brown, Viswanadham Sridhara, Daniel R. Boutz, Maria D. Person, Edward M. Marcotte, Jeffrey E. Barrick, Claus O. Wilke
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background Post-translational modification (PTM) of proteins is central to many cellular processes across all domains of life, but despite decades of study and a wealth of genomic and proteomic data the biological function of many PTMs remai
Externí odkaz:
https://doaj.org/article/a47212c442df447d875b7d47b760d0a7
Autor:
John R Houser, Craig Barnhart, Daniel R Boutz, Sean M Carroll, Aurko Dasgupta, Joshua K Michener, Brittany D Needham, Ophelia Papoulas, Viswanadham Sridhara, Dariya K Sydykova, Christopher J Marx, M Stephen Trent, Jeffrey E Barrick, Edward M Marcotte, Claus O Wilke
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 8, p e1004400 (2015)
How do bacteria regulate their cellular physiology in response to starvation? Here, we present a detailed characterization of Escherichia coli growth and starvation over a time-course lasting two weeks. We have measured multiple cellular components,
Externí odkaz:
https://doaj.org/article/9de889c5ee104d68a308ff43690012fc
Autor:
Viswanadham Sridhara, Austin G Meyer, Piyush Rai, Jeffrey E Barrick, Pradeep Ravikumar, Daniel Segrè, Claus O Wilke
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114608 (2014)
A widely studied problem in systems biology is to predict bacterial phenotype from growth conditions, using mechanistic models such as flux balance analysis (FBA). However, the inverse prediction of growth conditions from phenotype is rarely consider
Externí odkaz:
https://doaj.org/article/2b9f8dd1d3a44e7ca57f85fc6e46abba
Autor:
Dongli Guan, Viswanadham Sridhara, Nicola Segata, Yunlong Yang, Lorenzo Tosi, Biju Parekkadan, Polina Shpilker, H. Benjamin Larman
Publikováno v:
Nature biomedical engineering
As the catalogue of sequenced genomes and metagenomes continues to grow, massively parallel approaches for the comprehensive and functional analysis of gene products and regulatory elements are becoming increasingly valuable. Current strategies to sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e27c5ac9b97fed1b4d876cc833e0c34
https://doi.org/10.1038/s41551-017-0092
https://doi.org/10.1038/s41551-017-0092
Autor:
Maria D. Person, Daniel R. Boutz, Viswanadham Sridhara, Claus O. Wilke, Colin W. Brown, Edward M. Marcotte, Jeffrey E. Barrick
Publikováno v:
BMC Genomics
BMC Genomics, Vol 18, Iss 1, Pp 1-21 (2017)
BMC Genomics, Vol 18, Iss 1, Pp 1-21 (2017)
BackgroundPost-translational modification (PTM) of proteins is central to many cellular processes across all domains of life, but despite decades of study and a wealth of genomic and proteomic data the biological function of many PTMs remains unknown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6e7c21a5f4531e70fb978fa185e0bfb
http://europepmc.org/articles/PMC5392934
http://europepmc.org/articles/PMC5392934
Autor:
Brown, Colin, Viswanadham Sridhara, Boutz, Daniel, Person, Maria, Marcotte, Edward, Barrick, Jeffrey, Wilke, Claus
Modified and unmodified counts across timepoints for all AA positions with a +16 Da modification to tryptophan, pooled by biological replicate. The plots show the total unmodified (green) and +16 Da modified (orange) PSM counts across all nine timepo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e64a3c048e1f291535f4af4783721d2f
Autor:
Brown, Colin, Viswanadham Sridhara, Boutz, Daniel, Person, Maria, Marcotte, Edward, Barrick, Jeffrey, Wilke, Claus
Fraction of total peptides across timepoints with an N-terminal alanine possessing a +42 Da modification. The plots show unmodified (green) and +42 Da modified (blue) PSM counts across all nine timepoints (x-axis) for the N-terminal position of all p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30d9769b2badd22fb88dda15be93d6fa
Autor:
Brown, Colin, Viswanadham Sridhara, Boutz, Daniel, Person, Maria, Marcotte, Edward, Barrick, Jeffrey, Wilke, Claus
Temporally variable modification for individual proteins with an N-terminal threonine possessing a +42 Da modification. The plots show unmodified (green) and +42 Da Modified (blue) PSM counts across all nine timepoints (x-axis) for the N-terminal pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca79223dbe3cef4d1f151af17584ab1a
Autor:
Brown, Colin, Viswanadham Sridhara, Boutz, Daniel, Person, Maria, Marcotte, Edward, Barrick, Jeffrey, Wilke, Claus
Modified and unmodified PSM counts for each AA position with a significantly stationary-phase biased +1 Da modification to asparagine. The plots show unmodified (green) and +1 Da modified (brown) PSM counts across all nine timepoints (x-axis) for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac844605c2edd1dd94784c25f90efa9
Autor:
Viswanadham Sridhara, Sean M. Carroll, Jeffrey E. Barrick, Daniel R. Boutz, Drew Vander Wood, Claus O. Wilke, Bartram L. Smith, Edward M. Marcotte, Christopher J. Marx, Craig S. Barnhart, Walter F. Lenoir, Aurko Dasgupta, Dariya K. Sydykova, Mehmet Umut Caglar, John R. Houser
Publikováno v:
Scientific Reports
Modern systems biology requires extensive, carefully curated measurements of cellular components in response to different environmental conditions. While high-throughput methods have made transcriptomics and proteomics datasets widely accessible and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77387fe424bcc22f431a1ad8aa1f6165