Serum Thyroid Function, Mortality and Disability in Advanced Old Age: The Newcastle 85+Study

Autor: Pearce, SHS, Razvi, S, Yadegarfar, ME, Martin-Ruiz, C, Kingston, A, Collerton, J, Visser, TJ, Kirkwood, TB, Jagger, C

Publikováno v: Journal of Clinical Endocrinology and Metabolism, 101(11), 4385-4394. Endocrine Society

Context: Perturbations in thyroid function are common in older individuals but their significance in the very old is not fully understood. Objective: This study sought to determine whether thyroid hormone status and variation of thyroid hormones with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1f237f24cab75c6cd47190a5743ddebc
https://pure.eur.nl/en/publications/9f8be09d-3c6d-4085-a495-33b7373d7599

Characterization of recombinant Xenopus laevis type I iodothyronine deiodinase: substitution of a proline residue in the catalytic center by serine (Pro132Ser) restores sensitivity to 6-propyl-2-thiouracil

Autor: Kuiper Gg,, Klootwijk W,, Morvan Dubois G,, Destree O,, Darras Vm,, Van Der Geyten S,, Demeneix B,, Visser Tj.,

Publikováno v: Endocrinology
Endocrinology, Endocrine Society, 2006, 147, pp.3519-29

In frogs such as Rana and Xenopus, metamorphosis does not occur in the absence of a functional thyroid gland. Previous studies indicated that coordinated development in frogs requires tissue and stage-dependent type II and type III iodothyronine deio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______212::6ef0272fc14a4542982e6cc454489b7c
https://hal.archives-ouvertes.fr/hal-00093459

Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters

Autor: Kester, Mha, Bulduk, S., Toor, H., Tibboel, D., Meinl, W., Glatt, H., Falany, Cn, Michael Coughtrie, Schuur, Ag, Brouwer, A., Visser, Tj

Publikováno v: Kester, M H A, Bulduk, S, van Toor, H, Tibboel, D, Meinl, W, Glatt, H, Falany, C N, Coughtrie, M W H, Schuur, A G, Brouwer, A & Visser, T J 2002, ' Potent inhibition of estrogen sulfotransferase by hydroxylated metabolites of polyhalogenated aromatic hydrocarbons reveals alternative mechanism for estrogenic activity of endocrine disrupters ', Journal of Clinical Endocrinology and Metabolism, vol. 87, no. 3, pp. 1142-1150 . https://doi.org/10.1210/jc.87.3.1142
ResearcherID
Journal of Clinical Endocrinology and Metabolism, 87(3), 1142-1150. Endocrine Society
Journal of Clinical Endocrinology and Metabolism, 87(3), 1142-1150. Oxford University Press

Polyhalogenated aromatic hydrocarbons (PHAHs), such as polychlorinated dibenzo-p-dioxins and dibenzofurans, polybrominated diphenylethers, and bisphenol A derivatives are persistent environmental pollutants, which are capable of interfering with repr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::175f2b6668c2715dfd1e9ece296a06bd
https://research.vu.nl/en/publications/65363a06-6510-4462-82d0-cd9e5e4cc9f7

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