Zobrazeno 1 - 10 of 100 pro vyhledávání: '"Visser GM"'
1
Tetra- versus Pentavalent Inhibitors of Cholera Toxin
Autor: Fu, O, Pukin, AV, Quarles van Ufford, HC, Branson, TR, Thies-Weesie, DME, Turnbull, WB, Visser, GM, Pieters, RJ
The five B-subunits (CTB5) of the Vibrio cholerae (cholera) toxin can bind to the intestinal cell surface so the entire AB5 toxin can enter the cell. Simultaneous binding can occur on more than one of the monosialotetrahexosylganglioside (GM1) units
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::4b98181796d8e65399093295bfecf07e
https://dspace.library.uu.nl/handle/1874/322956
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2
Carbon-11-labeled daunorubicin and verapamil for probing P-glycoprotein in tumors with PET
Autor: Elsinga, PH, Franssen, EJF, Hendrikse, NH, Fluks, L, Weemaes, AMA, vanderGraaf, WTA, deVries, GE, Visser, GM, Vaalburg, W
Publikováno v: Journal of Nuclear Medicine, 37(9), 1571-1575. SOC NUCLEAR MEDICINE INC
One of the mechanisms for multidrug resistance (MDR) of tumors is an overexpression of the P-glycoprotein (P-gp). The cytostatic agent daunorubicin and the modulator verapamil were labeled with C-11 to probe P-gp with PET. Methods: Carbon-11-daunorub
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a5f1417766f8fbff2433802cfc5c24d5
https://research.rug.nl/en/publications/8304e2fd-1184-4764-bec6-9e533ad96d39
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3
N-[F-18]-FLUOROALKYLATION OF NORAPORPHINES - MICROWAVE VERSUS THERMAL-TREATMENT
Autor: ZIJLSTRA, S, DEGROOT, TJ, KOK, LP, VISSER, GM, VAALBURG, W
Publikováno v: European Journal of Morphology, 33(2), 154-157
A comparable study of microwave versus thermal heating is described for the N-[F-18]-fluoroalkylation of noraporphines. As compared to thermal treatment, different products were obtained during microwave treatment. Thermal treatment resulted in the l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::012d89a09e9ca164e41191dfca160ddf
https://research.rug.nl/en/publications/56a58d0b-0379-42f6-8155-17a8790ad051
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5
QUALITY-CONTROL OF PURIFIED [O-18] TARGET WATER USING P-31 NMR
Autor: HULST, R, FERINGA, BL, SIERTSEMA, HK, FRANSSEN, EJF, VISSER, GM, VAALBURG, W
Publikováno v: Applied Radiation and Isotopes, 45(10), 1049-1050. PERGAMON-ELSEVIER SCIENCE LTD
This work describes a method based upon the derivatization of [O-18]H2O and subsequent analysis by means of P-13 NMR techniques to ensure accurate, cheap and fast analysis of the [O-18]-content of [O-18]-target water.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::2d41696dffbafe32beba13e811b70882
https://research.rug.nl/en/publications/ecbfc3ba-4b13-46a4-8930-8ff1d74ca90b
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6
APPLICATION OF LIQUID-CHROMATOGRAPHY COMBINED WITH MASS-SPECTROMETRY (LC-MS) TO ESTABLISH IDENTITY AND PURITY OF PET-RADIOPHARMACEUTICALS
Autor: FRANSSEN, EJF, LUURTSEMA, G, MEDEMA, J, VISSER, GM, JERONISMUSSHALINGH, CM, BRUINS, AP, VAALBURG, W
Publikováno v: Applied Radiation and Isotopes, 45(9), 937-940. PERGAMON-ELSEVIER SCIENCE LTD
This article describes the application of liquid chromatography combined with mass-spectrometry (LC-MS) as a new quality control tool for PET-radiopharmaceuticals. The final step in the production of 2-[F-18]fluoro-2-deoxy-D-glucose (F-18-FDG) is a p
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::69f15fbe964d5bfb1c8979560ad4321c
https://research.rug.nl/en/publications/69bc9016-e421-4f70-aa5e-55d7b6125cc9
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7
SYNTHESIS OF 6-ALPHA-[F-18]FLUOROPROGESTERONE - A FIRST STEP TOWARDS A POTENTIAL RECEPTOR-LIGAND FOR PET
Autor: DEGROOT, TJ, BRAKER, AH, ELSINGA, PH, VISSER, GM, VAALBURG, W
Publikováno v: Applied Radiation and Isotopes, 45(7), 811-813. PERGAMON-ELSEVIER SCIENCE LTD
6 alpha-[F-18]Fluoroprogesterone 3 was prepared by the BF3.Et(2) O-catalyzed reaction of progest-5 alpha,6 alpha-epoxy-3,20-bisketal 1 and [F-18]fluoride as a possible route for the in vivo visualization of progesterone receptors by PET. The radioche
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0f93706cf28b94d6727568119b76f65c
https://research.rug.nl/en/publications/05142fdb-d421-44d7-9f35-c043ccc8d49f
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8
BEHAVIOR OF REACTION MIXTURES UNDER MICROWAVE CONDITIONS - USE OF SODIUM-SALTS IN MICROWAVE-INDUCED N-[F-18]FLUOROALKYLATIONS OF APORPHINE AND TETRALIN DERIVATIVES
Autor: ZIJLSTRA, S, DEGROOT, TJ, KOK, LP, VISSER, GM, VAALBURG, W
Publikováno v: Journal of Organic Chemistry, 58(7), 1643-1645. AMER CHEMICAL SOC INC
Microwave treatment combined with manipulation of the ionic strength of the reaction mixture increases the radiochemical yield dramatically of N-[F-18]fluoroalkylations of secondary amines as compared to thermal heating.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::9d7f53b39fa28bd4c814e9fd95b4aa1c
https://research.rug.nl/en/publications/6d303165-88d9-4da2-b2ab-5356fd151680
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9
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10
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