Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Visopo Harawa"'
Autor:
Isobel S. Walker, Saber Dini, Elizabeth H. Aitken, Timon Damelang, Wina Hasang, Agersew Alemu, Anja T. R. Jensen, Janavi S. Rambhatla, D. Herbert Opi, Michael F. Duffy, Eizo Takashima, Visopo Harawa, Takafumi Tsuboi, Julie A. Simpson, Wilson Mandala, Terrie E. Taylor, Karl B. Seydel, Amy W. Chung, Stephen J. Rogerson
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) proteins are expressed on the surface of infected erythrocytes, mediating parasite sequestration in the vasculature. PfEMP1 is a major target of protective antibodies,
Externí odkaz:
https://doaj.org/article/207469fd56754378a72987ad51f59013
Autor:
Dumizulu Tembo, Visopo Harawa, Tam C. Tran, Louise Afran, Malcolm E. Molyneux, Terrie E. Taylor, Karl B. Seydel, Tonney Nyirenda, David G. Russell, Wilson Mandala
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Although pro-inflammatory cytokines are involved in the clearance of Plasmodium falciparum during the early stages of the infection, increased levels of these cytokines have been implicated in the pathogenesis of severe malaria. A
Externí odkaz:
https://doaj.org/article/52f1e7ea82e6445991b2942845a3a8ad
Autor:
Dumizulu Tembo, Visopo Harawa, Tam C. Tran, Louise Afran, Malcolm E. Molyneux, Terrie E. Taylor, Karl B. Seydel, Tonney Nyirenda, David G. Russell, Wilson Mandala
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-2 (2023)
Externí odkaz:
https://doaj.org/article/6a99a5e40cc14c03bcae5a2380d8933e
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 184-193 (2021)
Cell-mediated responses to immunological stimuli are often localised in inflammatory sites and involve a number of cell types. These responses can be functionally characterised at the single-cell level on the basis of the types of cytokines expressed
Externí odkaz:
https://doaj.org/article/5217a2b8596e462e9ad970cc08eb342f
Autor:
Visopo Harawa, Madi Njie, Anne Kessler, Augustine Choko, Benjamin Kumwenda, Sam Kampondeni, Michael Potchen, Kami Kim, Anthony Jaworowski, Terrie Taylor, Wilson Mandala, Karl Seydel, Stephen Rogerson
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-11 (2018)
Abstract Background Cerebral malaria (CM) is often fatal, and severe brain swelling is a predictor of CM-related mortality. CM is characterized by elevated circulating pro-inflammatory cytokines TNF and IFN-γ and anti-inflammatory cytokine IL-10, ho
Externí odkaz:
https://doaj.org/article/953b007b412543b68394bee1a7a4d913
Autor:
Anne Kessler, Joseph J. Campo, Visopo Harawa, Wilson L. Mandala, Stephen J. Rogerson, Wenzhu B. Mowrey, Karl B. Seydel, Kami Kim
Publikováno v:
Malaria Journal, Vol 17, Iss 1, Pp 1-15 (2018)
Abstract Background Antibody immunity is thought to be essential to prevent severe Plasmodium falciparum infection, but the exact correlates of protection are unknown. Over time, children in endemic areas acquire non-sterile immunity to malaria that
Externí odkaz:
https://doaj.org/article/8c1adc5f43a446cca5bc9c33679406dd
Autor:
Visopo Harawa, Madi Njie, Thomas Keller, Kami Kim, Anthony Jaworowski, Karl Seydel, Stephen J Rogerson, Wilson Mandala
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223410 (2019)
Malaria is responsible for almost half a million deaths annually. The role of Vγ9Vδ2 γδ T cells in malaria is still unclear. Studies have reported an association between this cell subset and malaria symptoms and severity. Profiles of Vγ9Vδ2 γ
Externí odkaz:
https://doaj.org/article/91ca4bdc65b74d0c927629091e492205
Autor:
Sarah J Glennie, Enoch Sepako, David Mzinza, Visopo Harawa, David J C Miles, Kondwani C Jambo, Stephen B Gordon, Neil A Williams, Robert S Heyderman
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e25610 (2011)
Invasive pneumococcal disease (IPD) is a leading cause of morbidity and mortality in HIV-infected African adults. CD4 T cell depletion may partially explain this high disease burden but those with relatively preserved T cell numbers are still at incr
Externí odkaz:
https://doaj.org/article/fbe83137189c4250bec91b8e04ad2d3b
Publikováno v:
Molecular and Biochemical Parasitology
Highlights • Although substantial gains have been made in reducing malaria burden through various initiatives, it is still a major public health challenge. • Unlike other infectious diseases, there had not been any malaria vaccine until RTS,S/AS0
Publikováno v:
Current Research in Immunology, Vol 2, Iss, Pp 184-193 (2021)
Cell-mediated responses to immunological stimuli are often localised in inflammatory sites and involve a number of cell types. These responses can be functionally characterised at the single-cell level on the basis of the types of cytokines expressed