Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Vishwanath B Chachadi"'
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e57416 (2013)
Sialyl Lewis antigens are selectin ligands involved in leukocyte trafficking and cancer metastasis. Biosynthesis of these selectin ligands occurs by the sequential actions of several glycosyltransferases in the Golgi apparatus following synthesis of
Externí odkaz:
https://doaj.org/article/b247fd2b9bd64596a8ade7b8567ef9f0
Autor:
Shivakumar Belur, Narasimhappagari Jagadeesh, Vishwanath B. Chachadi, Shashikala R. Inamdar, Sanhita Roy
Publikováno v:
International Journal of Biological Macromolecules. 165:2089-2095
An L-fucose lectin, ANL from the corneal smears of a mycotic keratitis patient was reported earlier. Interaction of ANL with immortalized Human Corneal Epithelial Cells (HCECs) was studied in order to assign the role of ANL in pathogenesis. ANL showe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a91e4a8e6c2bdb81e5e8368287230597
https://doi.org/10.1016/j.ijbiomac.2020.10.020
https://doi.org/10.1016/j.ijbiomac.2020.10.020
Publikováno v:
Glycoconjugate Journal. 37:251-261
Sclerotium rolfsii lectin (SRL) exerts apoptotic effect against various cancer cells and an antitumor activity on mice with colon and breast cancer xenografts. The current study aimed to explore its exquisite carbohydrate specificity on human periphe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03b7270719ef95a6a4ef2dc4bdbf73f
https://doi.org/10.1007/s10719-019-09905-y
https://doi.org/10.1007/s10719-019-09905-y
Autor:
Narasimhappagari, Jagadeesh, Supreeth S, Kulkani, Vishwanath B, Chachadi, Sanhita, Roy, Shashikala R, Inamdar
Publikováno v:
Archives of microbiology. 204(11)
A lectin PCL, from Purpureocillium lilacinum a saprophytic, filamentous fungus was purified from the crude extract of the mycelia using 70% ammonium sulphate precipitation followed by affinity chromatography on mucin-Sepharose 4 B column. PCL is a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ec34f6312c0c99c98c4e2e5baa2940d7
https://pubmed.ncbi.nlm.nih.gov/36255493
https://pubmed.ncbi.nlm.nih.gov/36255493
Autor:
Vasundhara Budyhalamath, Lakshmi V. Umarji, Shashikala R. Inamdar, Tejashwini R. Nayanegali, Pi Wan Cheng, Bharamappa G. Pujari, Vishwanath B. Chachadi
Publikováno v:
LEGUME RESEARCH - AN INTERNATIONAL JOURNAL.
Food allergy caused by red kidney bean (Phaseolus vulgaris L.) is of serious health concern and is mainly due to its phytohemagglutinins (PHA) content. PHA can enter the circulation after oral uptake and cause IgE mediated allergy. However, studies d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::577c8a36f8fb4d2837919972e9f520b5
https://doi.org/10.18805/lr-4034
https://doi.org/10.18805/lr-4034
Publikováno v:
Glycobiology. 25:963-975
The sialyl Lewis a and x (sLe(a/x)) antigens frequently displayed on the surface of tumor cells are involved in metastasis. Their synthesis has been attributed to altered expression of selective glycosyltransferases. Identification of these glycosylt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dd8f026b54664503d663ff71bd2f86e
https://doi.org/10.1093/glycob/cwv030
https://doi.org/10.1093/glycob/cwv030
Publikováno v:
Biomedicinepharmacotherapy = Biomedecinepharmacotherapie. 93
Breast cancer known for its high metastatic potential is responsible for large mortality rate amongst women; hence it is imperative to search for effective anti-metastatic molecules despite anticancer drugs. The current study describes the potential
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f87c0eb9cd46d7d4efd51147cd6c336d
https://pubmed.ncbi.nlm.nih.gov/28686979
https://pubmed.ncbi.nlm.nih.gov/28686979
Publikováno v:
Journal of Biological Chemistry. 287:39564-39577
Core 2 N-acetylglucosaminyltransferase 1 (C2GnT1) is a key enzyme participating in the synthesis of core 2-associated sialyl Lewis x (C2-O-sLe(x)), a ligand involved in selectin-mediated leukocyte trafficking and cancer metastasis. To accomplish that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b416ce2a7840aa41e3eeeaaa68b19ff5
https://doi.org/10.1074/jbc.m112.346528
https://doi.org/10.1074/jbc.m112.346528
Publikováno v:
Glycoconjugate Journal. 29:525-537
Altered glycosylation is a universal feature of cancer cells and altered glycans can help cancer cells escape immune surveillance, facilitate tumor invasion, and increase malignancy. The goal of this study was to identify specific glycoenzymes, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::844904cdd563fc16366a4558dda2ef90
https://doi.org/10.1007/s10719-012-9428-8
https://doi.org/10.1007/s10719-012-9428-8
Autor:
Nagaraja N. Nagre, Sachin M. Eligar, Padma Shastry, Monica Barclays, Praveen Mahajan, Aravind Ingle, Anita M. Borges, Bale M Swamy, Lu-Gang Yu, Mohammed Azharuddin Savanur, Rajiv D. Kalraiya, Shashikala R. Inamdar, Vishwanath B. Chachadi, Jonathan M. Rhodes, Chen Chen
Publikováno v:
Glycobiology. 22:1227-1235
Glycan array analysis of Sclerotium rolfsii lectin (SRL) revealed its exquisite binding specificity to the oncofetal Thomsen-Friedenreich (Galβ1-3GalNAcα-O-Ser/Thr, T or TF) antigen and its derivatives. This study shows that SRL strongly inhibits t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623cfc3208f6c4a8f7019f3897583612
https://doi.org/10.1093/glycob/cws090
https://doi.org/10.1093/glycob/cws090