Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Vishnu Muraleedharan Saraswathy"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Adult zebrafish have an innate ability to recover from severe spinal cord injury. Here, we report a comprehensive single nuclear RNA sequencing atlas that spans 6 weeks of regeneration. We identify cooperative roles for adult neurogenesis an
Externí odkaz:
https://doaj.org/article/30ab23c2e826414fa40dd1efc4a77a16
Autor:
Vishnu Muraleedharan Saraswathy, Akshai Janardhana Kurup, Priyanka Sharma, Sophie Polès, Morgane Poulain, Maximilian Fürthauer
Publikováno v:
eLife, Vol 11 (2022)
Vertebrate Delta/Notch signaling involves multiple ligands, receptors and transcription factors. Delta endocytosis – a critical event for Notch activation – is however essentially controlled by the E3 Ubiquitin ligase Mindbomb1 (Mib1). Mib1 inact
Externí odkaz:
https://doaj.org/article/4469d7f4a21a4073811f8513b8baca22
Publikováno v:
bioRxiv
Adult zebrafish have an innate ability to regenerate spinal cord tissues within 6 to 8 weeks of injury. To achieve a comprehensive molecular understanding of neural repair mechanisms in zebrafish, we generated a single nuclear RNA sequencing atlas th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be5205f9473d933c512fa7bb525aac2
https://europepmc.org/articles/PMC10245778/
https://europepmc.org/articles/PMC10245778/
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Sensory neurons located in dorsal root ganglia (DRG) convey sensory information from peripheral tissue to the brain. After peripheral nerve injury, sensory neurons switch to a regenerative state to enable axon regeneration and functional recovery. Th
Autor:
Vishnu Muraleedharan Saraswathy, Lili Zhou, Anthony R. McAdow, Brooke Burris, Deepika Dogra, Sven Reischauer, Mayssa H. Mokalled
Publikováno v:
Cell Reports. 41:111705
Intrinsic and extrinsic inhibition of neuronal regeneration obstruct spinal cord (SC) repair in mammals. In contrast, adult zebrafish achieve functional recovery after complete SC transection. While studies of innate SC regeneration have focused on a
Autor:
Priyanka Sharma, Akshai Janardhana Kurup, Sophie Polès, Morgane Poulain, Vishnu Muraleedharan Saraswathy, Maximilian Fürthauer
Vertebrate Delta/Notch signaling involves multiple ligands, receptors and transcription factors. Delta endocytosis – a critical event for Notch activation – is however essentially controlled by the E3 Ubiquitin ligase Mindbomb1 (Mib1). Due to its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef103dd9b1115ebcdbc5b2b3e5c0530
https://doi.org/10.1101/2021.07.05.451064
https://doi.org/10.1101/2021.07.05.451064
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-18 (2019)
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9958. ⟨10.1038/s41598-019-46067-1⟩
Scientific Reports, 2019, 9 (1), pp.9958. ⟨10.1038/s41598-019-46067-1⟩
Scientific Reports
Scientific Reports, Nature Publishing Group, 2019, 9 (1), pp.9958. ⟨10.1038/s41598-019-46067-1⟩
Scientific Reports, 2019, 9 (1), pp.9958. ⟨10.1038/s41598-019-46067-1⟩
The morphogenesis of the nervous system requires coordinating the specification and differentiation of neural precursor cells, the establishment of neuroepithelial tissue architecture and the execution of specific cellular movements. How these aspect
The morphogenesis of the nervous system requires coordinating the specification and differentiation of neural precursor cells, the establishment of neuroepithelial tissue architecture and the execution of specific cellular movements. How these aspect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa13203297fc7399c0e34cfd06bc4e43
https://doi.org/10.1101/517714
https://doi.org/10.1101/517714
Autor:
Anthony R. McAdow, Dana Klatt Shaw, Lili Zhou, Brooke Burris, Samantha A. Morris, Mayssa H. Mokalled, Sabine Dietmann, Vishnu Muraleedharan Saraswathy, E. Butka
Publikováno v:
Dev Cell
Anti-regenerative scarring obstructs spinal cord repair in mammals and presents a major hurdle for regenerative medicine. In contrast, adult zebrafish possess specialized glial cells that spontaneously repair spinal cord injuries by forming a pro-reg