Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Vishnu Basetti"'
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 30:127288
Modifications at C6 and C7 positions of 3-cyanoquinolines 6 and 7 led to potent inhibitors of the ErbB family of kinases particularly against EGFRWT and Her4 enzymes in the radioisotope filter binding assay. The lead (4, SAB402) displayed potent dual
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cebf212236321480b54ac72b28a26cb
https://doi.org/10.1016/j.bmcl.2020.127288
https://doi.org/10.1016/j.bmcl.2020.127288
Publikováno v:
Heterocyclic Communications. 20:207-214
A tandem strategy for the synthesis of 7,12-dihydro-1,3,6,7,12-pentaazapleiadenes and 4-(2-aminophenoxy)pyrido[4,3-d]pyrimidin-5(6H)-ones from readily available starting materials has been developed.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3620166173afebd7e3b9028c5c3e3b0c
https://doi.org/10.1515/hc-2014-0065
https://doi.org/10.1515/hc-2014-0065
Publikováno v:
Tetrahedron Letters. 54:2014-2017
A novel methodology for the synthesis of tetracyclic benzo-pyridonaphthyridines, forming a C–C and a C–N bond in concentrated sulfuric acid at 70 °C in a one-pot is reported. The key substrates (9a–m) are prepared by reacting 2-chloro-6-(4-flu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1eb07db8325bee7b53427b2f4dae57cc
https://doi.org/10.1016/j.tetlet.2013.02.016
https://doi.org/10.1016/j.tetlet.2013.02.016
Publikováno v:
ChemInform. 46
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84fef5dfa7f9fbfec73bf529ebc4e8f8
https://doi.org/10.1002/chin.201546193
https://doi.org/10.1002/chin.201546193
Department of Discovery Chemistry, Aurigene Discovery Technologies Ltd., Hyderabad-500 049, Telangana, India E-mail : vijay_p@aurigene.com, potluri.vijay@gmail.com JNT University, Kukatpally, Hyderabad-500 072, Telangana, India new tandem three-step
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e9384f14885fb99721c35d1a569ab21
Autor:
Chandrasekhar Venna, Ravikrishna Vallakati, Aravinda B. Pulipaka, Sriram Rajgopal, Vamsee Krishna Chintakunta, Manohar Sharma Vedula, Venkateswarlu Akella, Sravan Kumar Teepireddy, Ajaya Kumar Reka, Venkata Adiseshu Kattuboina, Akash Khandelwal, Ramanujam Rajagopalan, Sreenu Jinnapally, Vijay V. Upreti, Prem Kumar Mamnoor, Gopalakrishnan Bulusu, Vishnu Basetti, Srinivas Rao Mamidi
Publikováno v:
European Journal of Medicinal Chemistry. 38:811-824
New styryl sulfone compounds have been synthesized and evaluated for their anti-proliferative activity. Among the compounds synthesized, one compound ( 7k ) has shown 51% tumor growth inhibition in mice implanted with HT-29 human carcinoma at 400 mg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d95213e5c6ac70beb937f4ec17389f
https://doi.org/10.1016/s0223-5234(03)00144-2
https://doi.org/10.1016/s0223-5234(03)00144-2
ChemInform Abstract: A Facile Synthesis of Tetracyclic Benzo-pyridonaphthyridines by Domino Reaction
Publikováno v:
ChemInform. 44
The three-step synthesis of title compounds (VI), which represent alkaloid skeletons, is based on the acid-mediated cyclization of key precursors (V).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0027516d00a32d4784bdb7e057f7332
https://doi.org/10.1002/chin.201329173
https://doi.org/10.1002/chin.201329173