Výsledky vyhledávání - "Vishala T. Neppalli"

Data from Antitumor Activity of the Investigational Proteasome Inhibitor MLN9708 in Mouse Models of B-cell and Plasma Cell Malignancies

Purpose: The clinical success of the first-in-class proteasome inhibitor bortezomib (VELCADE) has validated the proteasome as a therapeutic target for treating human cancers. MLN9708 is an investigational proteasome inhibitor that, compared with bort

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf51cd992431bfa10c2e6773dbd8053
https://doi.org/10.1158/1078-0432.c.6520107

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Supplementary Table 1-2 from Antitumor Activity of the Investigational Proteasome Inhibitor MLN9708 in Mouse Models of B-cell and Plasma Cell Malignancies

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https://doi.org/10.1158/1078-0432.22444227.v1

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Pevonedistat, a NEDD8-activating enzyme inhibitor, is active in mantle cell lymphoma and enhances rituximab activity in vivo

Autor: Cory Mavis, Natalie M Czuczman, Juan Gu, Song Liu, Francisco J. Hernandez-Ilizaliturri, Pavel Klener, Myron S. Czuczman, Qiang Hu, Sarah Frys, Petra Vockova, Matthew J. Barth, Vishala T. Neppalli

Publikováno v: Blood. 127:1128-1137

Mantle cell lymphoma (MCL) is characterized by an aggressive clinical course and inevitable development of refractory disease, stressing the need to develop alternative therapeutic strategies. To this end, we evaluated pevonedistat (MLN4924), a novel

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https://doi.org/10.1182/blood-2015-04-640920

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Ofatumumab Plus Hypercvad/MA Induction Leads to High Rates of Minimal Residual Disease (MRD) Negativity in Patients with Newly Diagnosed Mantle Cell Lymphoma, Results of a Phase 2 Study

Autor: Angela Kader, Vishala T. Neppalli, Sheila N.J. Sait, Joseph D. Tario, Paul K. Wallace, Jenna Nichols, Suchitra Sundaram, Alan D. Hutson, Nishitha Reddy, Pallawi Torka, Francisco J. Hernandez-Ilizaliturri, Cory Mavis, Adrienne Groman, AnneMarie W. Block, Bora E. Baysal

Publikováno v: Blood. 134:2817-2817

Background: Minimal residual disease (MRD) status is an independent prognostic marker for response duration in patients with mantle cell lymphoma (MCL). Rituximab-based therapy led to a molecular remission (MR) in 48% young MCL patients treated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d94c78b9042562168030bfea91568616
https://doi.org/10.1182/blood-2019-123488

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Reappraisal of the provisional entity primary cutaneous CD4+ small/medium pleomorphic T-cell lymphoma: A series of 10 adult and pediatric patients and review of the literature

Autor: Christian L. Baum, Vishala T. Neppalli, Brian K. Link, Brian L. Swick, Vincent Liu

Publikováno v: Journal of the American Academy of Dermatology. 65:739-748

Background Primary cutaneous CD4 + small/medium-sized pleomorphic T-cell lymphoma (PCSM-TCL) was defined as a provisional entity in the 2005 World Health Organization—European Organization for Research and Treatment of Cancer classification of cuta

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https://doi.org/10.1016/j.jaad.2010.07.028

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Antitumor activity of the investigational proteasome inhibitor MLN9708 in mouse models of B-cell and plasma cell malignancies

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 17(23)

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https://pubmed.ncbi.nlm.nih.gov/21903769

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Dextran removal by plasmapheresis in a kidney-pancreas transplant recipient with dextran 40-induced osmotic nephrosis

Autor: Elizabeth Kelley, Annette J. Schlueter, Vishala T. Neppalli, Christie P. Thomas, Aash P. Bhatt

Publikováno v: American journal of kidney diseases : the official journal of the National Kidney Foundation. 57(4)

Osmotic nephrosis with acute kidney injury can follow the administration of colloid volume expanders and other hypertonic solutions. In the kidney transplant setting, such agents may be used in the donor before organ procurement and in the recipient

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https://pubmed.ncbi.nlm.nih.gov/21257240

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IL-6 and MYC collaborate in plasma cell tumor formation in mice

Autor: Dong-Mi Shin, Hartmut Goldschmidt, Vishala T. Neppalli, Herbert C. Morse, Siegfried Janz, Wendy Dubois, Sebastian Rutsch

Publikováno v: Blood. 115(9)

Interleukin-6 (IL-6) plays a critical role in the natural history of human plasma cell neoplasms (PCNs), such as plasma cell myeloma and plasmacytoma (PCT). IL-6 is also at the center of neoplastic plasma cell transformation in BALB/c (C) mice carryi

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https://pubmed.ncbi.nlm.nih.gov/20018915

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Distinct CD30 Expression Patterns In Germinal Center B-Cell (GCB) and Non-GCB Diffuse Large B-Cell Lymphoma (DLBCL)

Autor: Shipra Gandhi, Vishala T. Neppalli, George Deeb, Myron S. Czuczman, Francisco J Hernandez-Ilizaliturri

Publikováno v: Blood. 122:5064-5064

Background DLBCL is the most common type of non-Hodgkin lymphoma, which demonstrates morphologic, immunophenotypic, molecular, and clinical heterogeneity. Gene expression profiling studies define two molecular subtypes of DLBCL, namely germinal cente

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https://doi.org/10.1182/blood.v122.21.5064.5064

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