Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Visakh Prabhakar"'
Publikováno v:
Neuroscience & Biobehavioral Reviews. 64:311-325
5HT3 receptors (5HT3Rs) have long been identified as a potential target for antidepressants. Several studies have reported that antagonism of 5HT3Rs produces antidepressant-like effects. However, the exact role of 5HT3Rs and the mode of antidepressan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8bb1ba4712e893fa6f988464b076338
https://doi.org/10.1016/j.neubiorev.2016.03.001
https://doi.org/10.1016/j.neubiorev.2016.03.001
Publikováno v:
CNS & Neurological Disorders - Drug Targets. 14:1317-1327
The delivery of drugs to brain is a daunting task due to the presence of multiple protective barriers. Nanoparticles (NPs), due to their ability to deliver and accumulate drugs in brain by crossing the blood brain barrier, have emerged as effective b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff7925e1b628f8df3050484848f8425f
https://doi.org/10.2174/1871527314666150821112411
https://doi.org/10.2174/1871527314666150821112411
Publikováno v:
Indian Journal of Pharmacology
Diabetes associated depression is a largely understudied field which nonetheless carries a significant disease burden. The very low therapeutic efficacy of the existing conventional drugs with poor outcome may be, in part, due to uncertainty of the m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b498185f104b68b1138836b7802852fd
http://europepmc.org/articles/PMC4375817
http://europepmc.org/articles/PMC4375817
Publikováno v:
Pakistan journal of pharmaceutical sciences. 29(1)
An over production of reactive oxygen species beyond basal levels generated continuously in the body as part of natural metabolic processes often results in serious and diverse disease conditions including cancer. Chalcones are known to possess good
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::45ada7d0b732703b2edd97435a820274
https://pubmed.ncbi.nlm.nih.gov/26826830
https://pubmed.ncbi.nlm.nih.gov/26826830
Publikováno v:
Free Radicals and Antioxidants. 1:82-86
Introduction: Over the past decade, herbal and ayurvedic drugs have become a subject of world importance, with both medicinal and economical implications. The relatively lower incidence of adverse reactions to plant preparations compared to modern ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce222894cb4c1ceabc382f7fc5b1b1e7
https://doi.org/10.5530/ax.2011.4.13
https://doi.org/10.5530/ax.2011.4.13
Autor:
Mahesh Radhakrishnan, Prateek Kanade, Visakh Prabhakar, Yeshwant Kurhe, Deepali Gupta, Devadoss Thangaraj
To investigate the antidepressant-like effects of a novel 5-HT3 receptor antagonist N-(benzo[d]thiazol-2-yl)-3-methoxyquinoxalin-2-carboxamide (6z) in acute and chronic murine models of depression.5-HT3 receptor antagonism was examined in guinea pig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8de8263454f2c7dbcd040af3e404b21b
https://europepmc.org/articles/PMC4261126/
https://europepmc.org/articles/PMC4261126/
Autor:
Amit Naskar, Kochupurackal P. Mohanakumar, Visakh Prabhakar, Raghavendra Singh, Debashis Dutta
Publikováno v:
Journal of pineal research. 58(3)
L-3,4-dihydroxyphenylalanine (L-DOPA) reduces symptoms of Parkinson's disease (PD), but suffers from serious side effects on long-term use. Melatonin (10-30 mg/kg, 6 doses at 10 hr intervals) was investigated to potentiate L-DOPA therapeutic effects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e029f8b195155b8e4c5e71be3c645b
https://pubmed.ncbi.nlm.nih.gov/25626558
https://pubmed.ncbi.nlm.nih.gov/25626558
Synthesis, anti-inflammatory and antioxidant activity of ring-A-monosubstituted chalcone derivatives
Publikováno v:
IndraStra Global.
A library of ring-A-monosubstituted chalcone derivatives (4a-4i, 5a and 5b) was designed and synthesised. The structures as well as the identities of these compounds were established on the basis of spectral (1H NMR, 13C NMR, FT-IR and Mass) and elem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fb7cb6d795a0ddafda3aad74bb96410
https://igi.indrastra.com/items/show/82273
https://igi.indrastra.com/items/show/82273
Publikováno v:
Indian Journal of Pharmaceutical Sciences
The characterization and classification of smokeless tobacco products has been a continuously evolving process. This is based on a number of different parameters like nicotine content, moisture content, amount of heavy metals, pH, and in vitro cytoto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a23d48f298d6fe520eb5dee792874ef
https://pubmed.ncbi.nlm.nih.gov/24082341
https://pubmed.ncbi.nlm.nih.gov/24082341
Publikováno v:
Value in Health. 18:A575
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8253efb563aa536969cca5090a2a7267
https://doi.org/10.1016/j.jval.2015.09.1907
https://doi.org/10.1016/j.jval.2015.09.1907