Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Virve Pitkänen"'
Autor:
Filip S. Ekholm, Suvi-Katriina Ruokonen, Marina Redón, Virve Pitkänen, Anja Vilkman, Juhani Saarinen, Jari Helin, Tero Satomaa, Susanne K. Wiedmer
Publikováno v:
Separations, Vol 6, Iss 1, p 1 (2018)
Antibody-drug conjugates (ADCs) are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer. The idea behind the ADC technology is remarkable as it combines the highly s
Externí odkaz:
https://doaj.org/article/ce3bcce3ae8246aabae69be02a0c9af4
Autor:
Tero Satomaa, Henna Pynnönen, Anja Vilkman, Titta Kotiranta, Virve Pitkänen, Annamari Heiskanen, Bram Herpers, Leo S. Price, Jari Helin, Juhani Saarinen
Publikováno v:
Antibodies, Vol 7, Iss 2, p 15 (2018)
Antibody-drug conjugates (ADCs) offer a combination of antibody therapy and specific delivery of potent small-molecule payloads to target cells. The properties of the ADC molecule are determined by the balance of its components. The efficacy of the p
Externí odkaz:
https://doaj.org/article/67567be6149d424694c29c74025dd073
Autor:
Tero Satomaa, Filip S. Ekholm, Marina Redón, Virve Pitkänen, Susanne K. Wiedmer, Juhani Saarinen, Jari Helin, Anja Vilkman, Suvi-Katriina Ruokonen
Publikováno v:
Separations, Vol 6, Iss 1, p 1 (2018)
Separations
Volume 6
Issue 1
Separations
Volume 6
Issue 1
Antibody-drug conjugates (ADCs) are promising state-of-the-art biopharmaceutical drugs for selective drug-delivery applications and the treatment of diseases such as cancer. The idea behind the ADC technology is remarkable as it combines the highly s
Autor:
Jari Helin, Bram Herpers, Virve Pitkänen, Leo S. Price, Juhani Saarinen, Annamari Heiskanen, Tero Satomaa, Henna Pynnönen, Titta Kotiranta, Anja Vilkman
Publikováno v:
Antibodies
Antibodies, Vol 7, Iss 2, p 15 (2018)
Antibodies; Volume 7; Issue 2; Pages: 15
Antibodies, Vol 7, Iss 2, p 15 (2018)
Antibodies; Volume 7; Issue 2; Pages: 15
Antibody-drug conjugates (ADCs) offer a combination of antibody therapy and specific delivery of potent small-molecule payloads to target cells. The properties of the ADC molecule are determined by the balance of its components. The efficacy of the p
Autor:
Céline Nicolazzi, Alexia Tellier, Jan Pinkas, Marc Trombe, Severine Clavier, Annamari Heiskanen, Veronique Blanc, Olli Aitio, Raffaele Baffa, Stephane Guerif, Tero Satomaa, Matteo Fassan, Anne Caron, Nathalie Karst, Chantal Carrez, Juhani Saarinen, Virve Pitkänen
Publikováno v:
Cancer Research. 79:235-235
SAR566658 antibody drug conjugate (ADC) is a humanized DS6 (huDS6) antibody conjugated through a cleavable linker to the cytotoxic maytansinoid derivative DM4 that has been evaluated in the clinical setting. The purpose of our work was; 1) characteri
Autor:
Ilja Ritamo, Werner Reutter, Saara Laitinen, Leena Valmu, Milla Lampinen, Alison V. Nairn, Jarkko Räbinä, Kelley W. Moremen, Suvi Natunen, Virve Pitkänen, Heli Suila
Publikováno v:
Glycobiology. 23:1004-1012
There is an increasing interest in the modification of cell surface glycosylation to improve the properties of therapeutic cells. For example, glycosylation affects the biodistribution of mesenchymal stromal cells (MSCs). Metabolic glycoengineering i
Autor:
Juhani Saarinen, Filip S. Ekholm, Anja Vilkman, Tero Satomaa, Virve Pitkänen, Henna Pynnönen, Jari Helin
Publikováno v:
ChemMedChem. 11(22)
Antibody–drug conjugates (ADCs) are promising alternatives to naked antibodies for selective drug-delivery applications and treatment of diseases such as cancer. Construction of ADCs relies upon site-selective, efficient and mild conjugation techno
Autor:
Anita Laitinen, Tero Satomaa, Leena Valmu, Jari Natunen, Saara Laitinen, Halina Miller-Podraza, Heidi Anderson, Annamari Heiskanen, Tia Hirvonen, Suvi Natunen, Virve Pitkänen, Heli Suila
Publikováno v:
Journal of molecular cell biology. 3(2)
Umbilical cord blood (UCB) is an efficient and valuable source of hematopoietic stem cells (HSCs) for transplantation. In addition to HSCs it harbours low amounts of mesenchymal stem cells (MSCs). No single marker to identify cord blood-derived stem