SARS-CoV-2 infection and replication in human gastric organoids

Autor: Hans Clevers, Camilla Luni, Giovanni Giuseppe Giobbe, Anna Manfredi, Lucio Di Filippo, Matteo Pagliari, Vivian S. W. Li, Brendan C. Jones, Paolo De Coppi, Hannah T. Stuart, Francesco Bonfante, Valentina Panzarin, Nikhil Thapar, Alessio Bortolami, Onelia Gagliano, Silvia Perin, Alessandro Filippo Pellegata, Georg A. Busslinger, Davide Cacchiarelli, Elisa Zambaiti, Cecilia Laterza, Simon Eaton, Eva Mazzetto, Chiara Colantuono, Nicola Elvassore

Publikováno v: Nature Communications
Nature Communications, 12(1). Nature Publishing Group
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)

COVID-19 typically manifests as a respiratory illness, but several clinical reports have described gastrointestinal symptoms. This is particularly true in children in whom gastrointestinal symptoms are frequent and viral shedding outlasts viral clear

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214a7a33c9ff862ebb1470fec7376cd4
http://hdl.handle.net/11585/838769

Nucleocapsid protein recruitment to replication-transcription complexes plays a crucial role in coronaviral life cycle

Autor: Cong, Yingying, Ulasli, Mustafa, Schepers, Hein, Mauthe, Mario, V'kovski, Philip, Kriegenburg, Franziska, Thiel, Volker, de Haan, Cornelis A M, Reggiori, Fulvio, LS Virologie, dI&I I&I-1

Publikováno v: Journal of Virology, 94(4). American Society for Microbiology
Cong, Y, Ulasli, M, Schepers, H, Mauthe, M, V'kovski, P, Kriegenburg, F, Thiel, V, de Haan, C A M & Reggiori, F 2020, ' Nucleocapsid Protein Recruitment to Replication-Transcription Complexes Plays a Crucial Role in Coronaviral Life Cycle ', Journal of Virology, vol. 94, no. 4 . https://doi.org/10.1128/JVI.01925-19
Journal of Virology
Journal of Virology, 94(4):ARTN e01925-19. American Society for Microbiology

CoVs have long been regarded as relatively harmless pathogens for humans. Severe respiratory tract infection outbreaks caused by severe acute respiratory syndrome CoV and Middle East respiratory syndrome CoV, however, have caused high pathogenicity a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb52fc32af7765ef8d58e1bde122ec3a
https://dspace.library.uu.nl/handle/1874/395019

Investigation of the role of GBF1 in the replication of positive-sense single-stranded RNA viruses

Autor: Laurence Cocquerel, Yves Rouillé, Didier Hober, Rayan Farhat, Sandrine Belouzard, Juliette Ferlin, Antoine Bertin, Jean Dubuisson

Publikováno v: Journal of General Virology
Journal of General Virology, Microbiology Society, 2018, 99 (8), pp.1086-1096. ⟨10.1099/jgv.0.001099⟩
Journal of General Virology, 2018, 99 (8), pp.1086-1096. ⟨10.1099/jgv.0.001099⟩

International audience; GBF1 has emerged as a host factor required for the replication of positive-sense single-stranded RNA viruses of different families, but its mechanism of action is still unknown. GBF1 is a guanine nucleotide exchange factor for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f61a159d161901a3885c57f1e24dc7b
https://hal.archives-ouvertes.fr/hal-02113930

Cytomegalovirus and HIV Persistence: Pouring Gas on the Fire

Autor: Christophe Vanpouille, Aaron Christensen-Quick, Sara Gianella, Andrea Lisco

Publikováno v: Christensen-Quick, Aaron; Vanpouille, Christophe; Lisco, Andrea; & Gianella, Sara. (2017). Cytomegalovirus and HIV Persistence: Pouring Gas on the Fire. AIDS Research and Human Retroviruses, 33(S1), S23-s30. doi: 10.1089/aid.2017.0145. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/9vn4h9q2
AIDS research and human retroviruses, vol 33, iss S1

The inherent stability of a small population of T cells that are latently infected with HIV despite antiretroviral therapy (ART) remains a stubborn obstacle to an HIV cure. By exploiting the memory compartment of our immune system, HIV maintains pers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2555f8c2584b528b56baa106610ca51
https://europepmc.org/articles/PMC5684659/

Role of seipin in lipid droplet morphology and hepatitis C virus life cycle

Autor: Catherine Fauvelle, Stéphanie Conzelmann, Kaori Minehira, Emilie Branche, V. Kaddai, Francesco Negro, Sophie Clément, Tujana Boldanova, Birke Bartosch

Publikováno v: Journal of General Virology, Vol. 94, No Pt 10 (2013) pp. 2208-14

Infectious hepatitis C virus (HCV) particle assembly starts at the surface of lipid droplets, cytoplasmic organelles responsible for neutral fat storage. We analysed the relationship between HCV and seipin, a protein involved in lipid droplet maturat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bb3ad158772d5ea8fb6c485cc658371
https://doi.org/10.1099/vir.0.054593-0