Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers

Autor: Chereau, Fanny, Madec, Yoann, Sabin, Caroline, Obel, Niels, Ruiz-Mateos, Ezequiel, Chrysos, Georgios, Fidler, Sarah, Lehmann, Clara, Zangerle, Robert, Wittkop, Linda, Reiss, Peter, Hamouda, Osamah, Perez, Vicente Estrada, Leal, Manuel, Mocroft, Amanda, De Olalla, Patricia Garcia, Ammassari, Adriana, Monforte, Antonella D'Arminio, Mussini, Cristina, Segura, Ferran, Castagna, Antonella, Cavassini, Matthias, Grabar, Sophie, Morlat, Philippe, De Wit, Stéphane, Lambotte, Olivier, Meyer, Laurence, Judd, Ali, Touloumi, Giota, Warszawski, Josiane, Dabis, François, Krause, Murielle Mary, Ghosn, Jade, Leport, Catherine, Wit, Ferdinand, Prins, Maria, Bucher, Heiner, Gibb, Diana, Fätkenheuer, Gerd, Del Amo, Julia, Thorne, Claire, Kirk, Ole, Stephan, Christoph, Pérez-Hoyos, Santiago, Bartmeyer, Barbara, Chkhartishvili, Nikoloz, Noguera-Julian, Antoni, Antinori, Andrea, Brockmeyer, Norbert, Prieto, Luis, Conejo, Pablo Rojo, Soriano-Arandes, Antoni, Battegay, Manuel, Kouyos, Roger, Tookey, Pat, Casabona, Jordi, Miró, Jose M., Konopnick, Deborah, Goetghebuer, Tessa, Sönnerborg, Anders, Torti, Carlo, Teira, Ramon, Garrido, Myriam, Haerry, David, Miró, Jose Ma, Costagliola, Dominique, D'Arminio-Monforte, Antonella, Raben, Dorthe, Chêne, Geneviève, Barger, Diana, Schwimmer, Christine, Termote, Monique, Campbell, Maria, Frederiksen, Casper M., Friis-Møller, Nina, Kjaer, Jesper, Brandt, Rikke Salbøl, Berenguer, Juan, Bohlius, Julia, Bouteloup, Vincent, Cozzi-Lepri, Alessandro, Davies, Mary-Anne, Dorrucci, Maria, Dunn, David, Egger, Matthias, Furrer, Hansjakob, Guiguet, Marguerite, Leroy, Valériane, Lodi, Sara, Matheron, Sophie, Monge, Susana, Nakagawa, Fumiyo, Paredes, Roger, Phillips, Andrew, Puoti, Massimo, Rohner, Eliane, Schomaker, Michael, Smit, Colette, Sterne, Jonathan, Thiebaut, Rodolphe, Van Der Valk, Marc

Publikováno v: PLoS One
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
PLoS ONE, Vol 12, Iss 4, p e0173893 (2017)
PLoS ONE
PLoS ONE, Public Library of Science, 2017, 12 (4), pp.e0173893. ⟨10.1371/journal.pone.0173893⟩
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
PLoS ONE, 2017, 12 (4), pp.e0173893. ⟨10.1371/journal.pone.0173893⟩
PLoS ONE, 12(4). Public Library of Science
Chereau, F, Madec, Y, Sabin, C, Obel, N, Ruiz-Mateos, E, Chrysos, G, Fidler, S, Lehmann, C, Zangerle, R, Wittkop, L, Reiss, P, Hamouda, O, Estrada Perez, V, Leal, M, Mocroft, A, Garcia De Olalla, P, Ammassari, A, D'Arminio Monforte, A, Mussini, C, Segura, F, Castagna, A, Cavassini, M, Grabar, S, Morlat, P, De Wit, S, Lambotte, O, Meyer, L & HIV Controllers Project Working Group for the Collaboration of Observational HIV Epidemiological Research Europe (COHERE) in EuroCOORD 2017, ' Impact of CD4 and CD8 dynamics and viral rebounds on loss of virological control in HIV controllers ', PloS one, vol. 12, no. 4, e0173893 . https://doi.org/10.1371/journal.pone.0173893
PloS one, vol. 12, no. 4, pp. e0173893
Digital.CSIC. Repositorio Institucional del CSIC

[Objective] HIV controllers (HICs) spontaneously maintain HIV viral replication at low level without antiretroviral therapy (ART), a small number of whom will eventually lose this ability to control HIV viremia. The objective was to identify factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::0e5eb48805ed7ad153f7c947095c051b
https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6515

Secretion of Hepatitis C Virus Replication Intermediates Reduces Activation of Toll-Like Receptor 3 in Hepatocytes

Autor: Florian W. R. Vondran, Robert Thimme, Pascal Mutz, Oliver Grünvogel, Katharina Esser-Nobis, Volker Lohmann, Christoph Neumann-Haefelin, Daniel Gotthardt, Ji-Young Lee, Ralf Bartenschlager, Arianeb Mehrabi, Alexander H. Dalpke, Anna Reustle, Ombretta Colasanti, Volker Klöss, Marco Binder, Paul Schnitzler, Sandrine Belouzard, Ronald Koschny, Katrin Hoffmann, Jasper Hesebeck-Brinckmann, Jean Dubuisson

Publikováno v: Gastroenterology
Gastroenterology, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩
Gastroenterology, WB Saunders, 2018, 154 (8), pp.2237-2251.e16. ⟨10.1053/j.gastro.2018.03.020⟩

International audience; Background & Aims: Hepatitis C virus (HCV) infections most often result in chronic outcomes, although the virus constantly produces replication intermediates, in particular double-stranded RNA (dsRNA), representing potent indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cdb70da0420c330868ac469be32c258
https://doi.org/10.1053/j.gastro.2018.03.020

Long-lasting protective antiviral immunity induced by passive immunotherapies requires both neutralizing and effector functions of the administered monoclonal antibody

Autor: Henri-Alexandre Michaud, Mireia Pelegrin, Marc Plays, Laurent Gros, Marc Piechaczyk, Roudaina Nasser

Publikováno v: Journal of Virology
Journal of Virology, American Society for Microbiology, 2010, 84 (19), pp.10169--81. ⟨10.1128/JVI.00568-10⟩

Using FrCasEretrovirus-infected newborn mice as a model system, we have shown recently that a long-lasting antiviral immune response essential for healthy survival emerges after a short treatment with a neutralizing (667) IgG2a isotype monoclonal ant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e1cad11c12b2dc0797d21fd363c3be
https://hal.archives-ouvertes.fr/hal-02193587

Requirement for neutralizing antibodies to control bone marrow transplantation-associated persistent viral infection and to reduce immunopathology

Autor: Lang, K. S., Recher, M., Navarini, A. A., Freigang, S., Harris, N. L., van den Broek, M., Odermatt, B., Hengartner, H., Zinkernagel, R. M.

Bone marrow transplantation (BMT) is commonly used in the treatment of leukemia, however its therapeutic application is partly limited by the high incidence of associated opportunistic infections. We modeled this clinical situation by infecting mice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______185::f171e286a28cb8bf458a242be19bcd96
https://infoscience.epfl.ch/record/143012