Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium

Autor: V’kovski, Philip, Gultom, Mitra, Kelly, Jenna N., Steiner, Silvio, Russeil, Julie, Mangeat, Bastien, Cora, Elisa, Pezoldt, Joern, Holwerda, Melle, Kratzel, Annika, Laloli, Laura, Wider, Manon, Portmann, Jasmine, Tran, Thao, Ebert, Nadine, Stalder, Hanspeter, Hartmann, Rune, Gardeux, Vincent, Alpern, Daniel, Deplancke, Bart, Thiel, Volker, Dijkman, Ronald

Publikováno v: V'kovski, P, Gultom, M, Kelly, J N, Steiner, S, Russeil, J, Mangeat, B, Cora, E, Pezoldt, J, Holwerda, M, Kratzel, A, Laloli, L, Wider, M, Portmann, J, Tran, T, Ebert, N, Stalder, H, Hartmann, R, Gardeux, V, Alpern, D, Deplancke, B, Thiel, V & Dijkman, R 2021, ' Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium ', PLoS Biology, vol. 19, no. 3, pp. e3001158 . https://doi.org/10.1371/journal.pbio.3001158
PLoS Biology, Vol 19, Iss 3, p e3001158 (2021)
PLoS Biology
V'kovski, Philip; Gultom, Mitra; Kelly, Jenna N.; Steiner, Silvio; Russeil, Julie; Mangeat, Bastien; Cora, Elisa; Pezoldt, Joern; Holwerda, Melle; Kratzel, Annika; Laloli, Laura; Wider, Manon; Portmann, Jasmine; Tran, Thao; Ebert, Nadine; Stalder, Hanspeter; Hartmann, Rune; Gardeux, Vincent; Alpern, Daniel; Deplancke, Bart; ... (2021). Disparate temperature-dependent virus-host dynamics for SARS-CoV-2 and SARS-CoV in the human respiratory epithelium. PLoS biology, 19(3), e3001158. Public Library of Science 10.1371/journal.pbio.3001158

Since its emergence in December 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has spread globally and become a major public health burden. Despite its close phylogenetic relationship to SARS-CoV, SARS-CoV-2 exhibits increased hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1e97f361c4afac4c5c8942c079ec89bd
https://pure.au.dk/portal/da/publications/disparate-temperaturedependent-virushost-dynamics-for-sarscov2-and-sarscov-in-the-human-respiratory-epithelium(231596e1-bb3e-401e-bc1b-a7d52c536053).html

Methylene Blue has a potent antiviral activity against SARS-CoV-2 and H1N1 influenza virus in the absence of UV-activation in vitro

Autor: Caroline Tapparel, Thomas Cerny, Chiara Medaglia, Andreas Cerny, Erich H Cerny, Valeria Cagno, Arnaud Charles-Antoine Zwygart

Publikováno v: Scientific Reports, Vol. 11, No 1 (2021) P. 14295
Scientific reports, vol. 11, no. 1, pp. 14295
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports

Methylene blue is an FDA (Food and Drug Administration) and EMA (European Medicines Agency) approved drug with an excellent safety profile. It displays broad-spectrum virucidal activity in the presence of UV light and has been shown to be effective i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6020a29ad34beedd3ef3bc09748b0f69
https://archive-ouverte.unige.ch/unige:154384

Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc

Autor: Davey M. Smith, Susan J. Little, Douglas D. Richman, Sara Gianella, Josué Pérez-Santiago, Antoine Chaillon, Parris Jordan, Joel O. Wertheim, Caroline Ignacio, Steven M. Lada, Maile Y. Karris, Sanjay Mehta

Publikováno v: Journal of virology, vol 92, iss 3
Chaillon, Antoine; Gianella, Sara; Lada, Steven M; Perez-Santiago, Josué; Jordan, Parris; Ignacio, Caroline; et al.(2018). Size, Composition, and Evolution of HIV DNA Populations during Early Antiretroviral Therapy and Intensification with Maraviroc.. Journal of virology, 92(3). doi: 10.1128/JVI.01589-17. UC Office of the President: Research Grants Program Office (RGPO). Retrieved from: http://www.escholarship.org/uc/item/2dz5q4q8

Residual viremia is common during antiretroviral therapy (ART) and could be caused by ongoing low-level virus replication or by release of viral particles from infected cells. ART intensification should impact ongoing viral propagation but not virion

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a5db9c6ca94addc5ddb77c1d14d6fc0
https://escholarship.org/uc/item/2dz5q4q8

Hypoxia-induced human deoxyribonuclease I is a cellular restriction factor of hepatitis B virus

Autor: Camille Hallez, Cristina M. Dorobantu, Mohamed S Bouzidi, Valérie Thiers, Vincent Lucansky, Jean-Pierre Vartanian, Xiongxiong Li, Simon Wain-Hobson, Raphael Gaudin, Rodolphe Suspène

Publikováno v: Nature Microbiology
Nature Microbiology, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩
Nature Microbiology, Nature Publishing Group, 2019, 4 (7), pp.1196-1207. ⟨10.1038/s41564-019-0405-x⟩

International audience; Numerous human APOBEC3 cytidine deaminases have proven to be, inter alia, host cell restriction factors for retroviruses and hepadnaviruses. Although they can bind to genomic RNA and become encapsidated, they are only catalyti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5b9df1192a8473ace5d62d1f522f99
https://hal-pasteur.archives-ouvertes.fr/pasteur-02424852

In vitro evaluation of novel reverse transcriptase inhibitors TAF (tenofovir alafenamide) and OBP-601 (2,3-didehydro-3-deoxy-4-ethynylthymidine) against multi-drug resistant primary isolates of HIV-2

Autor: Inês Bártolo, Perpétua Gomes, Inês V. Pinto, Nuno Taveira, Umbelina Caixas, Pedro Borrego, Fátima Gonçalves

Publikováno v: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Agência para a Sociedade do Conhecimento (UMIC)-FCT-Sociedade da Informação
instacron:RCAAP

New antiretroviral drugs are needed to treat HIV-2 infected patients failing therapy. Herein, we evaluate the activity of novel reverse transcriptase inhibitors tenofovir alafenamide (TAF) and OBP-601(2,3-didehydro-3-deoxy-4-ethynylthymidine) against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad33099c170bad98790b16b08156a38
https://hdl.handle.net/10400.26/30647