Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Virpi V. Smith"'
Publikováno v:
Frontiers in Endocrinology, Vol 2 (2011)
BackgroundLoss of function mutations in the genes encoding the pancreatic β-cell ATP-sensitive potassium (KATP) channel are identified in approximately 80% of patients with diazoxide-unresponsive hyperinsulinaemic-hypoglycaemia (HH). For a small num
Externí odkaz:
https://doaj.org/article/3158ae4c327d4754867c5dcbf2dbfa18
Autor:
Oliver Blankenstein, Khalid Hussain, Michael Ashworth, Sarah E. Flanagan, Sian Ellard, Virpi V. Smith, Ritika R. Kapoor, Dunia Ismail, Agostino Pierro
Publikováno v:
J Clin Endocrinol Metab
BACKGROUND: Congenital hyperinsulinism (CHI) is a cause of persistent hypoglycemia due to unregulated insulin secretion from pancreatic β-cells. Histologically, there are two major subgroups, focal and diffuse. Focal CHI is typically unresponsive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::323f02bb1ed8f8372c93436b06b6f46c
https://doi.org/10.1210/jc.2011-1628
https://doi.org/10.1210/jc.2011-1628
Autor:
Khalid Hussain, Ori Ron, Simon Eaton, Paolo De Coppi, Michael Ashworth, Augusto Zani, Agostino Pierro, Oliver Blankenstein, Dunia Ismail, Virpi V. Smith, Wolgang Mohnike, Shireen Anne Nah, Giorgia Totonelli
Publikováno v:
Journal of Pediatric Surgery. 46:204-208
Background/Purpose In congenital hyperinsulinism (CHI) of infancy, the use of preoperative fluorine-18-l-3,4-dihydroxyphenylalanine–positron emission tomography–computed tomography ( 18 F-DOPA-PET-CT) scan has recently been reported. The aim of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920331ba373632902470ed27de5d6136
https://doi.org/10.1016/j.jpedsurg.2010.09.093
https://doi.org/10.1016/j.jpedsurg.2010.09.093
Autor:
Virpi V. Smith, Khalid Hussain, Catherine M. Hall, Indraneel Banerjee, Ritika R. Kapoor, Sian Ellard, Sarah E. Flanagan
Publikováno v:
Clinical Genetics
Flanagan SE, Kapoor RR, Banerjee I, Hall C, Smith VV, Hussain K, Ellard S. Dominantly acting ABCC8 mutations in patients with medically unresponsive hyperinsulinaemic hypoglycaemia. Recessive inactivating mutations in the ABCC8 and KCNJ11 genes encod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe8e762f29c1efe1a2d08e540d5d527
http://europepmc.org/articles/PMC3375476
http://europepmc.org/articles/PMC3375476
Autor:
Keith J. Lindley, W Michael Bisset, Peter J. Milla, Virpi V. Smith, Adam Jaffe, Michela G. Schäppi, Fevronia Kiparissi
Publikováno v:
Journal of Pediatric Gastroenterology and Nutrition, Vol. 49, No 1 (2009) pp. 42-51
Cystic fibrosis (CF) is a multisystem disorder intrinsically associated with inflammation of mucosal surfaces. Because inflammation can result in enteric neuromuscular dysfunction we hypothesized that terminal ileitis in patients with CF may predispo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4898c99aff2d32762c1c866abc9d85
https://doi.org/10.1097/mpg.0b013e318186d35a
https://doi.org/10.1097/mpg.0b013e318186d35a
Autor:
Sue Williams, Daniela Knafelz, Peter J. Milla, Michela G. Schäppi, Osvaldo Borrelli, Virpi V. Smith, Keith J. Lindley
Publikováno v:
Journal of Pediatric Gastroenterology and Nutrition, Vol. 47, No 4 (2008) pp. 472-80
BACKGROUND AND AIMS: Functional dyspepsia in childhood is commonly triggered by food allergen in sensitised individuals. We investigated the topography of eosinophils and mast cells in gastric antral lamina propria, the interaction of mast cell produ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95903d2c53c6bc64c4132a9a0b78fd8a
https://doi.org/10.1097/mpg.0b013e318186008e
https://doi.org/10.1097/mpg.0b013e318186008e
Publikováno v:
Critical Care Medicine. 36:1564-1572
Moderate hypothermia is protective when applied throughout experimental intestinal ischemia and reperfusion (I/R). However, therapeutic intervention is usually possible only after ischemia has occurred. The aim of this study was to evaluate moderate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abef3b9e8044d314f24a6c94160f9b6f
https://doi.org/10.1097/ccm.0b013e3181709e9f
https://doi.org/10.1097/ccm.0b013e3181709e9f
Autor:
Virpi V. Smith
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 45:S93-S96
Congenital and acquired disorders of the enteric neuromusculature are relatively uncommon in childhood, with the exception of Hirschsprung disease. Despite this, a number of histologically well-defined phenotypes of enteric neuromuscular disease are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d133abe0d71670960b50945fdbaa3dec
https://doi.org/10.1097/mpg.0b013e31812e650e
https://doi.org/10.1097/mpg.0b013e31812e650e
Autor:
Mamoun Elawad, Marco Londei, A Schwarzer, Neil J. Sebire, SE Kirkham, Peter J. Milla, Keith J. Lindley, M Furman, Susan Hill, K Binnie, Virpi V. Smith, Neil P. Shah, Ida Ricciardelli
Publikováno v:
Journal of Pediatric Gastroenterology & Nutrition. 42:245-248
Fulminating acute ulcerative colitis (UC) is a potentially life threatening medical emergency. Up to 30% of individuals respond poorly to corticosteroids alone and second line medical or surgical therapies are indicated. We describe the successful us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80c88bb59ed3093098b553d1900b22a
https://doi.org/10.1097/01.mpg.0000189347.32796.c5
https://doi.org/10.1097/01.mpg.0000189347.32796.c5
Publikováno v:
Journal of Surgical Research. 129:288-291
Background The detrimental effects of intestinal ischemia reperfusion (IIR) injury on secondary organs including the liver, lungs, heart, and kidney have been widely investigated in animal models. However, the effect of IIR on the central nervous sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2145fc92de687b8f7eda55820d25e1a
https://doi.org/10.1016/j.jss.2005.04.036
https://doi.org/10.1016/j.jss.2005.04.036