Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Virpi, Muhonen"'
Autor:
Michael Gasik, Alexandra Zühlke, Anne-Marie Haaparanta, Virpi Muhonen, Kaisa Laine, Yevgen Bilotsky, Minna Kellomäki, Ilkka Kiviranta
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 6 (2018)
Scaffolds for articular cartilage repair have to be optimally biodegradable with simultaneous promotion of hyaline cartilage formation under rather complex biomechanical and physiological conditions. It has been generally accepted that scaffold struc
Externí odkaz:
https://doaj.org/article/6962faa45acf4a13b6238c2d0de0896a
Autor:
Jani Puhakka, Teemu Paatela, Markus Hannula, Eve Salonius, Virpi Muhonen, Ilkka Kiviranta, Anne-Marie Haaparanta, Anna Meller, Anna Vasara
Publikováno v:
Cartilage
Objective Large articular cartilage defects are a challenge to regenerative surgery. Biomaterial scaffolds might provide valuable support for restoration of articulating surface. The performance of a composite biomaterial scaffold was evaluated in a
Autor:
Jani Puhakka, Eve Salonius, Teemu Paatela, Virpi Muhonen, Anna Meller, Anna Vasara, Hannu Kautiainen, Jussi Kosola, Ilkka Kiviranta
Publikováno v:
Cartilage. 13(1)
Objective The arthroscopic and histological International Cartilage Repair Society (ICRS) scores are designed to evaluate cartilage repair quality. Arthroscopic ICRS score can give a maximum score of 12 and the histological score can give values betw
Autor:
Anna Meller, Jussi Kosola, Anna Vasara, Jani Puhakka, Teemu Paatela, Eve Salonius, Virpi Muhonen, Hannu Kautiainen, Ilkka Kiviranta
Background: The International Cartilage Repair Society (ICRS) score was designed for arthroscopic use to evaluate the quality of cartilage repair. Purpose: To evaluate the reliability of the ICRS scoring system using an animal cartilage repair model.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876b4e490bd3025f7e358e968872116a
http://hdl.handle.net/10138/344101
http://hdl.handle.net/10138/344101
Autor:
Matti Korhonen, Leena Kontturi, Eve Salonius, Anita Laitinen, Virpi Muhonen, Johanna Nystedt, Anne-Marie Haaparanta, Ilkka Kiviranta
Publikováno v:
Journal of cellular physiology. 235(4)
Cell therapy combined with biomaterial scaffolds is used to treat cartilage defects. We hypothesized that chondrogenic differentiation bone marrow-derived mesenchymal stem cells (BM-MSCs) in three-dimensional biomaterial scaffolds would initiate cart
Autor:
Eve Salonius, Anna Meller, Mimmi Björkman, Ilkka Kiviranta, Tuomo Pyhältö, Anna Vasara, Virpi Muhonen, Markus Hannula, Minna Kellomäki, Anne-Marie Haaparanta, Juha Töyräs, Ville Ellä, Elina Järvinen, Teemu Paatela
Publikováno v:
Journal of Orthopaedic Research. 34:745-753
The purpose of this study was to investigate the potential of a novel recombinant human type II collagen/polylactide scaffold (rhCo-PLA) in the repair of full-thickness cartilage lesions with autologous chondrocyte implantation technique (ACI). The f
Autor:
Johanna Nystedt, Gerjo J.V.M. van Osch, Virpi Muhonen, Roberto Narcisi, Ilkka Kiviranta, Matti Korhonen
Publikováno v:
Journal of Tissue Engineering and Regenerative Medicine. 11:843-854
Recombinant human type II collagen (rhCII) hydrogel was tested as a xeno-free micro-environment for the chondrogenesis of human bone marrow-derived mesenchymal stromal cells (BM-MSCs). The rhCII hydrogels were seeded with BM-MSCs and cultured in a xe
Autor:
Arto Urtti, Leena-Stiina Kontturi, Roberto Narcisi, Johanna Nystedt, Matti Korhonen, Virpi Muhonen, Ilkka Kiviranta, Gerjo J. V. M. van Osch, Maria S. Skog
Publikováno v:
Cytotechnology, 67(5), 905-919. Springer Netherlands
Current cell-based cartilage therapies relay on articular cartilage-derived autologous chondrocytes as a cell source, which possesses disadvantages, such as, donor site morbidity and dedifferentiation of chondrocytes during in vitro expansion. Due to
Autor:
Arto Urtti, Leena-Stiina Kontturi, Marjo Yliperttula, Estelle Collin, Elina Järvinen, Ilkka Kiviranta, Abhay Pandit, Virpi Muhonen
Publikováno v:
Drug Delivery and Translational Research. 4:149-158
In this study, chondrocytes were encapsulated into an injectable, in situ forming type II collagen/hyaluronic acid (HA) hydrogel cross-linked with poly(ethylene glycol) ether tetrasuccinimidyl glutarate (4SPEG) and supplemented with the transforming
Publikováno v:
Bio-Medical Materials and Engineering. 24:1549-1553
Biomaterial scaffolds have been used in autologous chondrocyte implantation to facilitate the repair of large lesions and to advance the formation of articular cartilage [Exp. Biol. Med. (Maywood) 237(1) (2012), 10-17]. Biomaterial scaffolds are usua